Pathways > Lipopolysaccharide Biosynthesis
Page last updated: 2024-10-06

Lipopolysaccharide Biosynthesis

Proteins (41)

ProteinSynonymsTaxonomy
UDP-galactopyranose mutaseUGM; EC 5.4.99.9; UDP-GALP mutase; Uridine 5-diphosphate galactopyranose mutaseEscherichia coli K-12
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferaseUDP-N-acetylglucosamine acyltransferase; EC 2.3.1.129Escherichia coli K-12
UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferaseUDP-3-O-(3-OHC14)-GlcN N-acyltransferase; EC 2.3.1.191; Protein FirA; Rifampicin resistance protein; UDP-3-O-(3-hydroxytetradecanoyl)glucosamine N-acyltransferaseEscherichia coli K-12
UDP-3-O-acyl-N-acetylglucosamine deacetylaseUDP-3-O-acyl-GlcNAc deacetylase; EC 3.5.1.108; Protein EnvA; UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylaseEscherichia coli K-12
Bifunctional protein GlmUEscherichia coli K-12
Lipopolysaccharide heptosyltransferase 1EC 2.-.-.-Escherichia coli K-12
Lipopolysaccharide 1,2-glucosyltransferaseEC 2.4.1.58Escherichia coli K-12
UDP-2,3-diacylglucosamine hydrolaseEC 3.6.1.54; UDP-2,3-diacylglucosamine diphosphatase; UDP-2,3-diacylglucosamine pyrophosphataseEscherichia coli K-12
Lipopolysaccharide 1,2-N-acetylglucosaminetransferaseEC 2.4.1.56Escherichia coli K-12
Lipid A biosynthesis myristoyltransferaseEC 2.3.1.243; Kdo(2)-lauroyl-lipid IV(A) myristoyltransferaseEscherichia coli K-12
Phosphocarrier protein HPrHistidine-containing proteinEscherichia coli K-12
Tetraacyldisaccharide 4'-kinaseEC 2.7.1.130; Lipid A 4'-kinaseEscherichia coli K-12
2-dehydro-3-deoxyphosphooctonate aldolaseEC 2.5.1.55; 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase; KDO-8-phosphate synthase; KDO 8-P synthase; KDOPS; Phospho-2-dehydro-3-deoxyoctonate aldolaseEscherichia coli K-12
Lipopolysaccharide core biosynthesis protein RfaGEC 2.4.-.-; Glucosyltransferase IEscherichia coli K-12
Phosphoglucosamine mutaseEC 5.4.2.10Escherichia coli K-12
Lipopolysaccharide core heptose(I) kinase RfaPEC 2.7.1.-Escherichia coli K-12
Lipopolysaccharide core heptose(II) kinase RfaYEC 2.7.1.-Escherichia coli K-12
3-deoxy-manno-octulosonate cytidylyltransferaseEC 2.7.7.38; CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthaseEscherichia coli K-12
Lipopolysaccharide 1,3-galactosyltransferaseEC 2.4.1.44; Lipopolysaccharide 3-alpha-galactosyltransferaseEscherichia coli K-12
Lipopolysaccharide export system ATP-binding protein LptBEC 7.5.2.-Escherichia coli K-12
3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsCEC 3.1.3.45; KDO 8-P phosphataseEscherichia coli K-12
3-deoxy-D-manno-octulosonic acid transferaseKdo transferase; EC 2.4.99.12; EC 2.4.99.13; Bifunctional Kdo transferase; Kdo-lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase; Lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferaseEscherichia coli K-12
Lipid A biosynthesis lauroyltransferaseEC 2.3.1.241; Kdo(2)-lipid IV(A) lauroyltransferaseEscherichia coli K-12
LPS-assembly lipoprotein LptERare lipoprotein BEscherichia coli K-12
Lipopolysaccharide export system permease protein LptGEscherichia coli K-12
Lipopolysaccharide export system protein LptAEscherichia coli K-12
Lipopolysaccharide export system protein LptCEscherichia coli K-12
Lipopolysaccharide export system permease protein LptFEscherichia coli K-12
Lipid-A-disaccharide synthaseEC 2.4.1.182Escherichia coli K-12
Arabinose 5-phosphate isomerase GutQAPI; G-API; EC 5.3.1.13; Phosphosugar aldol-ketol isomeraseEscherichia coli K-12
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]EC 2.6.1.16; D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine--D-fructose-6-phosphate amidotransferaseEscherichia coli K-12
Lipopolysaccharide core heptosyltransferase RfaQEC 2.-.-.-Escherichia coli K-12
Lipopolysaccharide 1,6-galactosyltransferaseEC 2.4.1.-; UDP-D-galactose--(Glucosyl)lipopolysaccharide-alpha-1,3-D-galactosyltransferaseEscherichia coli K-12
LPS-assembly protein LptDOrganic solvent tolerance proteinEscherichia coli K-12
Kdo(2)-lipid A phosphoethanolamine 7''-transferaseEC 2.7.8.42; Phosphoethanolamine transferase EptBEscherichia coli K-12
ADP-heptose--LPS heptosyltransferase 2EC 2.-.-.-; ADP-heptose--LPS heptosyltransferase IIEscherichia coli K-12
Arabinose 5-phosphate isomerase KdsDAPI; L-API; EC 5.3.1.13Escherichia coli K-12
ATP-dependent lipid A-core flippaseEC 7.5.2.6; Lipid A export ATP-binding/permease protein MsbA; Lipid flippaseEscherichia coli K-12
PTS system mannose-specific EIIAB componentEC 2.7.1.191; EIIAB-Man; EIII-ManEscherichia coli K-12
PTS system mannose-specific EIIC componentEII-P-Man; EIIC-Man; Mannose permease IIC componentEscherichia coli K-12
PTS system mannose-specific EIID componentEII-M-Man; EIID-Man; Mannose permease IID componentEscherichia coli K-12

Compounds (28)

CompoundDescription
hydronium ion
Orthophosphate
acetic acidProduct of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed)
uridine diphosphateA uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety.
glutamic acidA non-essential amino acid naturally occurring in the L-form. Glutamic acid is the most common excitatory neurotransmitter in the CENTRAL NERVOUS SYSTEM.
Adenosine TriphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
glutamineA non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from GLUTAMIC ACID and AMMONIA. It is the principal carrier of NITROGEN in the body and is an important energy source for many cells.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
uridine monophosphate5'-Uridylic acid. A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
uridine triphosphateUridine 5'-(tetrahydrogen triphosphate). A uracil nucleotide containing three phosphate groups esterified to the sugar moiety.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Coenzyme A
phosphoenolpyruvateA monocarboxylic acid anion derived from selective deprotonation of the carboxy group of phosphoenolpyruvic acid. It is a metabolic intermediate in GLYCOLYSIS; GLUCONEOGENESIS; and other pathways.
lipid IVA
glucosamine 6-phosphateRN given refers to parent cpd
n-acetylglucosamine-1-phosphatefound in proteinase I from Dictyostelium discoideum
Uridine Diphosphate N-AcetylglucosamineServes as the biological precursor of insect chitin, of muramic acid in bacterial cell walls, and of sialic acids in mammalian glycoproteins.
cytidine monophosphateCytidine (dihydrogen phosphate). A cytosine nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
cytidine triphosphateCytidine 5'-(tetrahydrogen triphosphate). A cytosine nucleotide containing three phosphate groups esterified to the sugar moiety.
fructose-6-phosphateRN given refers to parent cpd with unspecified isomeric designation
1,2-didodecanoylglycerolRN given refers to cpd without isomeric designation
arabinose 5-phosphateRN given refers to (D)-isomer
lipid Xmonosaccharide precursor of E coli lipid A; structure given in first source; see also lipid A precursors, Salmonella
ribulose 5-phosphateRN given refers to cpd without isomeric designation
acetyl coenzyme aAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.
Plecoglossus altivelisSpecies of fish, in the family Osmeridae, found in Japan, Korea, Taiwan, and China.
pyrophosphate
cycloniteexplosive & convulsant; structure
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