| Protein | Synonyms | Taxonomy |
|---|
| Aspartate aminotransferase, mitochondrial | mAspAT; EC 2.6.1.1; EC 2.6.1.7; Fatty acid-binding protein; FABP-1; Glutamate oxaloacetate transaminase 2; Kynurenine aminotransferase 4; Kynurenine aminotransferase IV; Kynurenine--oxoglutarate transaminase 4; Kynurenine--oxoglutarate transaminase IV; Pl | Homo sapiens (human) |
| 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase | EC 4.1.1.45; Picolinate carboxylase | Homo sapiens (human) |
| Indoleamine 2,3-dioxygenase 1 | IDO-1; EC 1.13.11.52; Indoleamine-pyrrole 2,3-dioxygenase | Homo sapiens (human) |
| Indoleamine 2,3-dioxygenase 2 | IDO-2; EC 1.13.11.-; Indoleamine 2,3-dioxygenase-like protein 1; Indoleamine-pyrrole 2,3-dioxygenase-like protein 1 | Homo sapiens (human) |
| Kynureninase | EC 3.7.1.3; L-kynurenine hydrolase | Homo sapiens (human) |
| Kynurenine--oxoglutarate transaminase 3 | EC 2.6.1.7; Cysteine-S-conjugate beta-lyase 2; 4.4.1.13; Kynurenine aminotransferase 3; Kynurenine aminotransferase III; KATIII; Kynurenine--glyoxylate transaminase; 2.6.1.63; Kynurenine--oxoglutarate transaminase III | Homo sapiens (human) |
| Tryptophan 2,3-dioxygenase | TDO; EC 1.13.11.11; Tryptamin 2,3-dioxygenase; Tryptophan oxygenase; TO; TRPO; Tryptophan pyrrolase; Tryptophanase | Homo sapiens (human) |
| Kynurenine--oxoglutarate transaminase 1 | EC 2.6.1.7; Cysteine-S-conjugate beta-lyase; 4.4.1.13; Glutamine transaminase K; GTK; Glutamine--phenylpyruvate transaminase; 2.6.1.64; Kynurenine aminotransferase 1; Kynurenine aminotransferase I; KATI; Kynurenine--oxoglutarate transaminase I | Homo sapiens (human) |
| Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | KAT/AadAT; 2-aminoadipate aminotransferase; 2-aminoadipate transaminase; 2.6.1.39; Alpha-aminoadipate aminotransferase; AadAT; Kynurenine aminotransferase II; Kynurenine--oxoglutarate aminotransferase II; Kynurenine--oxoglutarate transaminase 2; 2.6.1.7; | Homo sapiens (human) |
| Kynurenine formamidase | KFA; KFase; EC 3.5.1.9; Arylformamidase; N-formylkynurenine formamidase; FKF | Homo sapiens (human) |
| Kynurenine 3-monooxygenase | EC 1.14.13.9; Kynurenine 3-hydroxylase | Homo sapiens (human) |
| 3-hydroxyanthranilate 3,4-dioxygenase | EC 1.13.11.6; 3-hydroxyanthranilate oxygenase; 3-HAO; h3HAO; 3-hydroxyanthranilic acid dioxygenase; HAD | Homo sapiens (human) |
| Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial | EC 1.2.4.2; Dehydrogenase E1 and transketolase domain-containing protein 1 | Homo sapiens (human) |
| Compound | Description |
|---|
| hydronium ion | |
| Cobalt | A trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis. |
| NADH | |
| Ammonium | |
| iron | A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN. |
| Chromium | A trace element that plays a role in glucose metabolism. It has the atomic symbol Cr, atomic number 24, and atomic weight 52. According to the Fourth Annual Report on Carcinogens (NTP85-002,1985), chromium and some of its compounds have been listed as known carcinogens. |
| Carbon Dioxide | A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. |
| Iron | A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN. |
| chlorine | An element with atomic symbol Cl, atomic number 17, and atomic weight 35, and member of the halogen family. |
| Zinc | A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn. |
| picolinate | |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| 1,5-dihydro-FAD | chromophore component of E coli DNA photolyase |
| nad | A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed) |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| alpha-Ketoglutarate | |
| formate | |
| Cadmium | An element with atomic symbol Cd, atomic number 48, and atomic weight 112.41. It is a metal and ingestion will lead to CADMIUM POISONING. |
| indole propionate | |
| anthranilate | |
| glutamate | |
| Quinolinate | |
| Cysteine | A thiol-containing non-essential amino acid that is oxidized to form CYSTINE. |
| Coenzyme A | |
| glutaryl-coenzyme A | |
| Flavin-Adenine Dinucleotide | A condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972) |
| heme | The color-furnishing portion of hemoglobin. It is found free in tissues and as the prosthetic group in many hemeproteins. |