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L-isoleucine biosynthesis II

Proteins (14)

ProteinSynonymsTaxonomy
Isopropylmalate/citramalate isomerase large subunitEC 4.2.1.33; EC 4.2.1.35; (R)-2-methylmalate dehydratase; (R)-citramalate dehydratase; 3-isopropylmalate dehydratase; Alpha-isopropylmalate dehydratase; Citraconate hydratase; Isopropylmalate isomerase; IPMI; Maleate hydratase; Malease; 4.2.1.31Methanocaldococcus jannaschii DSM 2661
Isopropylmalate/citramalate isomerase small subunitEC 4.2.1.33; EC 4.2.1.35; (R)-2-methylmalate dehydratase; (R)-citramalate dehydratase; 3-isopropylmalate dehydratase; Alpha-isopropylmalate dehydratase; Citraconate hydratase; Isopropylmalate isomerase; IPMI; Maleate hydratase; Malease; 4.2.1.31Methanocaldococcus jannaschii DSM 2661
3-isopropylmalate dehydratase small subunitEC 4.2.1.33; Alpha-IPM isomerase; IPMI; Isopropylmalate isomeraseLeptospira interrogans serovar Lai str. 56601
3-isopropylmalate dehydratase large subunitEC 4.2.1.33; Alpha-IPM isomerase; IPMI; Isopropylmalate isomeraseLeptospira interrogans serovar Lai str. 56601
Putative branched-chain-amino-acid aminotransferaseBCAT; EC 2.6.1.42; Transaminase BMethanothermobacter thermautotrophicus str. Delta H
Probable acetolactate synthase large subunitAHAS; EC 2.2.1.6; Acetohydroxy-acid synthase large subunit; ALSMethanococcus aeolicus
3-isopropylmalate dehydrogenaseEC 1.1.1.85; 3-IPM-DH; Beta-IPM dehydrogenase; IMDHLeptospira interrogans serovar Lai str. 56601
3-isopropylmalate/3-methylmalate dehydrogenaseEC 1.1.1.85; EC 1.1.1.n5; 3-isopropylmalate dehydrogenase; 3-IPM-DH; IMDH; IPMDH; Beta-IPM dehydrogenase; D-malate dehydrogenase [decarboxylating]; 1.1.1.83Methanocaldococcus jannaschii DSM 2661
Ketol-acid reductoisomerase (NADP(+))KARI; EC 1.1.1.86; Acetohydroxy-acid isomeroreductase; AHIR; Alpha-keto-beta-hydroxylacyl reductoisomerase; Ketol-acid reductoisomerase type 1; Ketol-acid reductoisomerase type IMethanothermobacter thermautotrophicus str. Delta H
(R)-citramalate synthase CimAEC 2.3.1.182Methanocaldococcus jannaschii DSM 2661
Dihydroxy-acid dehydrataseDAD; EC 4.2.1.9Methanothermobacter thermautotrophicus str. Delta H
Acetohydroxyacid synthase small subunit Methanococcus aeolicus
Branched-chain-amino-acid aminotransferase Methanococcus aeolicus Nankai-3
(R)-citramalate synthase CimAEC 2.3.1.182; LiCMSLeptospira interrogans serovar Lai str. 56601

Compounds (21)

CompoundDescription
hydronium ion
CobaltA trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis.
NADH
CopperA heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55.
ironA metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
ManganeseA trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
potassiumAn element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE.
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
NickelA trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
Pyruvic AcidAn intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
alpha-Ketoglutarate
2-ketobutyrate
glutamate
hydrogen cyanideHydrogen cyanide (HCN); A toxic liquid or colorless gas. It is found in the smoke of various tobacco products and released by combustion of nitrogen-containing organic materials.
Coenzyme A
Acetyl Coenzyme AAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.
imidazoleRN given refers to parent cpd