Page last updated: 2024-10-06

L-arginine degradation II (AST pathway)

Proteins (8)

ProteinSynonymsTaxonomy
Succinylornithine transaminase/acetylornithine aminotransferaseACOAT; SOAT; Succinylornithine aminotransferase; EC 2.6.1.11; EC 2.6.1.81Pseudomonas aeruginosa PAO1
N-succinylglutamate 5-semialdehyde dehydrogenaseEC 1.2.1.71; Succinylglutamic semialdehyde dehydrogenase; SGSDEscherichia coli K-12
Arginine N-succinyltransferaseAST; EC 2.3.1.109; AOSTEscherichia coli K-12
Arginine N-succinyltransferase subunit alphaARUAI; EC 2.3.1.109; AOST; ASTPseudomonas aeruginosa PAO1
Arginine N-succinyltransferase subunit betaEC 2.3.1.109; AOST; AST; ARUAIIPseudomonas aeruginosa PAO1
Succinylglutamate desuccinylaseEC 3.5.1.96Escherichia coli K-12
N-succinylarginine dihydrolaseEC 3.5.3.23Escherichia coli K-12
Succinylornithine transaminaseSOAT; EC 2.6.1.81; Carbon starvation protein C; Succinylornithine aminotransferaseEscherichia coli K-12

Compounds (13)

CompoundDescription
hydronium ion
ArginineAn essential amino acid that is physiologically active in the L-form.
Succinate
NADH
Ammonium
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
succinyl-coenzyme A
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
alpha-Ketoglutarate
CadaverineA foul-smelling diamine formed by bacterial decarboxylation of lysine.
glutamate
Coenzyme A