Page last updated: 2024-10-06

L-arginine degradation I (arginase pathway)

Proteins (8)

ProteinSynonymsTaxonomy
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrialP5C dehydrogenase; EC 1.2.1.88; Aldehyde dehydrogenase family 4 member A1; L-glutamate gamma-semialdehyde dehydrogenaseHomo sapiens (human)
Ornithine aminotransferase, mitochondrialEC 2.6.1.13; Ornithine delta-aminotransferase; Ornithine--oxo-acid aminotransferaseHomo sapiens (human)
Arginase-1EC 3.5.3.1; Liver-type arginase; Type I arginaseHomo sapiens (human)
Arginase-2, mitochondrialEC 3.5.3.1; Arginase II; Kidney-type arginase; Non-hepatic arginase; Type II arginaseHomo sapiens (human)
Ornithine aminotransferase, mitochondrialEC 2.6.1.13; Ornithine delta-aminotransferase; Ornithine--oxo-acid aminotransferaseArabidopsis thaliana (thale cress)
Arginase 1, mitochondrialEC 3.5.3.1; Agmatinase ARGAH1; 3.5.3.11; Arginine amidohydrolase 1; AtARGAH1Arabidopsis thaliana (thale cress)
ArginaseEC 3.5.3.1Agrobacterium fabrum str. C58
Ornithine aminotransferase Pinus sylvestris (Scots pine)

Compounds (14)

CompoundDescription
hydronium ion
ureaA compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.
ArginineAn essential amino acid that is physiologically active in the L-form.
NADH
ManganeseA trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
boric acid
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
iodoacetamideAn alkylating sulfhydryl reagent. Its actions are similar to those of iodoacetate.
3-hydroxybenzaldehyde
4-hydroxybenzaldehyde
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
alpha-Ketoglutarate
glutamate
Canavanine