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L-Threonine Degradation to Methylglyoxal

Proteins (2)

ProteinSynonymsTaxonomy
Primary amine oxidaseEC 1.4.3.21; 2-phenylethylamine oxidase; Copper amine oxidase; Tyramine oxidaseEscherichia coli K-12
L-threonine 3-dehydrogenaseTDH; EC 1.1.1.103; L-threonine dehydrogenaseEscherichia coli K-12

Compounds (11)

CompoundDescription
hydronium ion
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
NADH
threonineAn essential amino acid occurring naturally in the L-form, which is the active form. It is found in eggs, milk, gelatin, and other proteins.
Hydrogen PeroxideA strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
aminoacetoneRN given refers to parent cpd
2-amino-3-ketobutyrateunstable intermediate in threonine dehydrogenase-initiated pathway for threonine utilization; structure given in first source
NADA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
pyruvaldehydeAn organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals.