| Compound | Description |
|---|---|
| irinotecan | A semisynthetic camptothecin derivative that inhibits DNA TOPOISOMERASE I to prevent nucleic acid synthesis during S PHASE. It is used as an antineoplastic agent for the treatment of COLORECTAL NEOPLASMS and PANCREATIC NEOPLASMS. |
| RPR 121056 | metabolite of irinotecan; structure given in first source |
| sn 38 | |
| 7-ethyl-10-hydroxycamptothecin glucuronide |