Page last updated: 2024-10-06

Irinotecan Pathway, Pharmacodynamics

Proteins (13)

ProteinSynonymsTaxonomy
CholinesteraseEC 3.1.1.8; Acylcholine acylhydrolase; Butyrylcholine esterase; Choline esterase II; PseudocholinesteraseHomo sapiens (human)
DNA topoisomerase 1EC 5.6.2.1; DNA topoisomerase IHomo sapiens (human)
Canalicular multispecific organic anion transporter 1ATP-binding cassette sub-family C member 2; Canalicular multidrug resistance protein; Multidrug resistance-associated protein 2; 7.6.2.2Homo sapiens (human)
Broad substrate specificity ATP-binding cassette transporter ABCG2EC 7.6.2.2; ATP-binding cassette sub-family G member 2; Breast cancer resistance protein; CDw338; Mitoxantrone resistance-associated protein; Placenta-specific ATP-binding cassette transporter; Urate exporterHomo sapiens (human)
Liver carboxylesterase 1Acyl-coenzyme A:cholesterol acyltransferase; ACAT; Brain carboxylesterase hBr1; Carboxylesterase 1; CE-1; hCE-1; 3.1.1.1; Cholesteryl ester hydrolase; CEH; 3.1.1.13; Cocaine carboxylesterase; Egasyn; HMSE; Methylumbelliferyl-acetate deacetylase 1; 3.1.1.5Homo sapiens (human)
Cocaine esteraseEC 3.1.1.84; Carboxylesterase 2; CE-2; hCE-2; 3.1.1.1; Methylumbelliferyl-acetate deacetylase 2; 3.1.1.56Homo sapiens (human)
UDP-glucuronosyltransferase 1A9UGT1A9; EC 2.4.1.17; UDP-glucuronosyltransferase 1-9; UDPGT 1-9; UGT1*9; UGT1-09; UGT1.9; UDP-glucuronosyltransferase 1-I; UGT-1I; UGT1I; lugP4Homo sapiens (human)
UDP-glucuronosyltransferase 1A1 UGT1A1; EC 2.4.1.17; Bilirubin-specific UDPGT isozyme 1; hUG-BR1; UDP-glucuronosyltransferase 1-1; UDPGT 1-1; UGT1*1; UGT1-01; UGT1.1; UDP-glucuronosyltransferase 1A isoform 1Homo sapiens (human)
UDP-glucuronosyltransferase 1A3UGT1A3; EC 2.4.1.17; UDP-glucuronosyltransferase 1-3; UDPGT 1-3; UGT1*3; UGT1-03; UGT1.3; UDP-glucuronosyltransferase 1-C; UGT-1C; UGT1C; UDP-glucuronosyltransferase 1A isoform 3Homo sapiens (human)
UDP-glucuronosyltransferase 1A4UGT1A4; EC 2.4.1.17; Bilirubin-specific UDPGT isozyme 2; hUG-BR2; UDP-glucuronosyltransferase 1-4; UDPGT 1-4; UGT1*4; UGT1-04; UGT1.4; UDP-glucuronosyltransferase 1-D; UGT-1D; UGT1DHomo sapiens (human)
UDP-glucuronosyltransferase Homo sapiens (human)
ATP-binding cassette, sub-family B Homo sapiens (human)
UDP-glucuronosyltransferase Homo sapiens (human)

Compounds (1)

CompoundDescription
sn 38