Page last updated: 2024-10-06

Intracellular Signalling Through Prostacyclin Receptor and Prostacyclin

Proteins (8)

ProteinSynonymsTaxonomy
Myosin light chain kinase, smooth muscleMLCK; smMLCK; EC 2.7.11.18; Kinase-related protein; KRP; TelokinHomo sapiens (human)
Prostacyclin receptorProstaglandin I2 receptor; PGI receptor; PGI2 receptor; Prostanoid IP receptorHomo sapiens (human)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1Transducin beta chain 1Homo sapiens (human)
Adenylate cyclase type 2EC 4.6.1.1; ATP pyrophosphate-lyase 2; Adenylate cyclase type II; Adenylyl cyclase 2Homo sapiens (human)
cAMP-dependent protein kinase catalytic subunit betaPKA C-beta; EC 2.7.11.11Homo sapiens (human)
Guanine nucleotide-binding protein GAdenylate cyclase-stimulating G alpha proteinHomo sapiens (human)
Myosin light chain 3Cardiac myosin light chain 1; CMLC1; Myosin light chain 1, slow-twitch muscle B/ventricular isoform; MLC1SB; Ventricular myosin alkali light chain; Ventricular myosin light chain 1; VLCl; Ventricular/slow twitch myosin alkali light chain; MLC-lV/sbHomo sapiens (human)
Guanine nucleotide-binding protein G(T) subunit gamma-T1Transducin gamma chainHomo sapiens (human)

Compounds (5)

CompoundDescription
Orthophosphate
epoprostenolA prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from PROSTAGLANDIN ENDOPEROXIDES in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension (HYPERTENSION, PULMONARY).
Adenosine TriphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
Cyclic AMPAn adenine nucleotide containing one phosphate group which is esterified to both the 3'- and 5'-positions of the sugar moiety. It is a second messenger and a key intracellular regulator, functioning as a mediator of activity for a number of hormones, including epinephrine, glucagon, and ACTH.
pyrophosphate