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Intracellular Signalling Through Histamine H2 Receptor and Histamine

Proteins (9)

ProteinSynonymsTaxonomy
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP-1A; EC 3.1.3.16Homo sapiens (human)
Histamine H2 receptorH2R; HH2R; Gastric receptor IHomo sapiens (human)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1Transducin beta chain 1Homo sapiens (human)
Cyclic AMP-responsive element-binding protein 1CREB-1; cAMP-responsive element-binding protein 1Homo sapiens (human)
Adenylate cyclase type 2EC 4.6.1.1; ATP pyrophosphate-lyase 2; Adenylate cyclase type II; Adenylyl cyclase 2Homo sapiens (human)
cAMP-dependent protein kinase catalytic subunit betaPKA C-beta; EC 2.7.11.11Homo sapiens (human)
Guanine nucleotide-binding protein GAdenylate cyclase-stimulating G alpha proteinHomo sapiens (human)
Guanine nucleotide-binding protein G(T) subunit gamma-T1Transducin gamma chainHomo sapiens (human)
Ethylene-responsive transcription factor ESR1Protein DORNROSCHEN; Protein ENHANCER OF SHOOT REGENERATION 1Arabidopsis thaliana (thale cress)

Compounds (5)

CompoundDescription
Orthophosphate
Adenosine TriphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
histamineAn amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.
Cyclic AMPAn adenine nucleotide containing one phosphate group which is esterified to both the 3'- and 5'-positions of the sugar moiety. It is a second messenger and a key intracellular regulator, functioning as a mediator of activity for a number of hormones, including epinephrine, glucagon, and ACTH.
pyrophosphate