Pathways > Inositol phosphate metabolism
Page last updated: 2024-10-06

Inositol phosphate metabolism

Proteins (32)

ProteinSynonymsTaxonomy
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1EC 3.1.4.11; Phosphoinositide phospholipase C-delta-1; Phospholipase C-III; PLC-III; Phospholipase C-delta-1; PLC-delta-1Homo sapiens (human)
Inositol-trisphosphate 3-kinase AEC 2.7.1.127; Inositol 1,4,5-trisphosphate 3-kinase A; IP3 3-kinase A; IP3K A; InsP 3-kinase AHomo sapiens (human)
Inositol polyphosphate multikinaseEC 2.7.1.140; EC 2.7.1.151; EC 2.7.1.153; Inositol 1,3,4,6-tetrakisphosphate 5-kinaseHomo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1EC 3.1.4.11; PLC-148; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-II; PLC-II; Phospholipase C-gamma-1; PLC-gamma-1Homo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2EC 3.1.4.11; Phosphoinositide phospholipase C-gamma-2; Phospholipase C-IV; PLC-IV; Phospholipase C-gamma-2; PLC-gamma-2Homo sapiens (human)
Diphosphoinositol polyphosphate phosphohydrolase 1DIPP-1; EC 3.6.1.52; Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1; 3.6.1.-; Nucleoside diphosphate-linked moiety X motif 3; Nudix motif 3Homo sapiens (human)
Diphosphoinositol polyphosphate phosphohydrolase 3-betaDIPP-3-beta; DIPP3-beta; hDIPP3beta; EC 3.6.1.52; Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 3-beta; Diadenosine hexaphosphate hydrolase (AMP-forming); 3.6.1.60; Nucleoside diphosphate-linked moiety X motif 11; Nudix motif 11; hAps1Homo sapiens (human)
Diphosphoinositol polyphosphate phosphohydrolase 2DIPP-2; EC 3.6.1.52; Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 2; Nucleoside diphosphate-linked moiety X motif 4; Nudix motif 4Homo sapiens (human)
Inositol-tetrakisphosphate 1-kinaseEC 2.7.1.134; Inositol 1,3,4-trisphosphate 5/6-kinase; Inositol-triphosphate 5/6-kinase; Ins(1,3,4)P(3) 5/6-kinase; 2.7.1.159Homo sapiens (human)
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTENEC 3.1.3.16; EC 3.1.3.48; EC 3.1.3.67; Mutated in multiple advanced cancers 1; Phosphatase and tensin homologHomo sapiens (human)
5'-3' exonuclease PLD4EC 3.1.16.1; Choline phosphatase 4; Phosphatidylcholine-hydrolyzing phospholipase D4; Phospholipase D family member 4; Phospholipase D4; PLD 4Homo sapiens (human)
Calmodulin-1Homo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1EC 3.1.4.11; PLC-154; Phosphoinositide phospholipase C-beta-1; Phospholipase C-I; PLC-I; Phospholipase C-beta-1; PLC-beta-1Homo sapiens (human)
Inositol-trisphosphate 3-kinase BEC 2.7.1.127; Inositol 1,4,5-trisphosphate 3-kinase B; IP3 3-kinase B; IP3K B; InsP 3-kinase BHomo sapiens (human)
Diphosphoinositol polyphosphate phosphohydrolase 3-alphaDIPP-3-alpha; DIPP3-alpha; hDIPP3alpha; EC 3.6.1.52; Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 3-alpha; Diadenosine hexaphosphate hydrolase (AMP-forming); 3.6.1.60; Nucleoside diphosphate-linked moiety X motif 10; Nudix motif 10; hAps2Homo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2EC 3.1.4.11; Phosphoinositide phospholipase C-beta-2; Phospholipase C-beta-2; PLC-beta-2Homo sapiens (human)
Inositol oxygenaseEC 1.13.99.1; Aldehyde reductase-like 6; Kidney-specific protein 32; Myo-inositol oxygenase; MI oxygenase; Renal-specific oxidoreductaseHomo sapiens (human)
Myotubularin-related protein 7Inositol 1,3-bisphosphate phosphatase; 3.1.3.-; Phosphatidylinositol-3-phosphate phosphatase; 3.1.3.64Homo sapiens (human)
Inositol-pentakisphosphate 2-kinaseEC 2.7.1.158; IPK1 homolog; Inositol-1,3,4,5,6-pentakisphosphate 2-kinase; Ins(1,3,4,5,6)P5 2-kinase; InsP5 2-kinaseHomo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2EC 3.1.4.11; Phosphoinositide phospholipase C-eta-2; Phosphoinositide phospholipase C-like 4; PLC-L4; Phospholipase C-like protein 4; Phospholipase C-eta-2; PLC-eta2Homo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4hPLCD4; EC 3.1.4.11; Phosphoinositide phospholipase C-delta-4; Phospholipase C-delta-4; PLC-delta-4Homo sapiens (human)
Inositol polyphosphate 1-phosphataseIPP; IPPase; EC 3.1.3.57Homo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4EC 3.1.4.11; Phosphoinositide phospholipase C-beta-4; Phospholipase C-beta-4; PLC-beta-4Homo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1EC 3.1.4.11; Pancreas-enriched phospholipase C; Phosphoinositide phospholipase C-epsilon-1; Phospholipase C-epsilon-1; PLC-epsilon-1Homo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3EC 3.1.4.11; Phosphoinositide phospholipase C-beta-3; Phospholipase C-beta-3; PLC-beta-3Homo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1EC 3.1.4.11; Phosphoinositide phospholipase C-eta-1; Phospholipase C-eta-1; PLC-eta-1; Phospholipase C-like protein 3; PLC-L3Homo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1EC 3.1.4.11; Phosphoinositide phospholipase C-zeta-1; Phospholipase C-zeta-1; PLC-zeta-1; Testis-development protein NYD-SP27Homo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3EC 3.1.4.11; Phosphoinositide phospholipase C-delta-3; Phospholipase C-delta-3; PLC-delta-3Homo sapiens (human)
Inositol-trisphosphate 3-kinase CEC 2.7.1.127; Inositol 1,4,5-trisphosphate 3-kinase C; IP3 3-kinase C; IP3K C; InsP 3-kinase CHomo sapiens (human)
Myotubularin-related protein 9Inactive phosphatidylinositol 3-phosphatase 9Homo sapiens (human)
Inositol-3-phosphate synthase 1IPS 1; EC 5.5.1.4; Myo-inositol 1-phosphate synthase; MI-1-P synthase; MIP synthase; hIPS; Myo-inositol 1-phosphate synthase A1; hINO1Homo sapiens (human)
Multiple inositol polyphosphate phosphatase 1EC 3.1.3.62; 2,3-bisphosphoglycerate 3-phosphatase; 2,3-BPG phosphatase; 3.1.3.80; Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase; Ins(1,3,4,5)P(4) 3-phosphataseHomo sapiens (human)

Compounds (24)

CompoundDescription
hydronium ion
inositol 1-phosphate
CalciumA basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
ironA metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
Orthophosphate
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
inositolAn isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
inositol 1,4,6-trisphosphateinhibits (1,4,5)P3/(1,3,4,5)P4-polyphosphate 5-phosphatase; structure in first source
inositol 1,4-bis(phosphate)induced in human platelets by thrombin; RN given refers to cpd without isomeric designation
inositol 4-phosphateRN given refers to (DL-myo)-isomer
inositol 3-phosphateRN given refers to (myo)-isomer
inositol 3,4-bisphosphateRN given for (D)-isomer
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
Glucose-6-PhosphateAn ester of glucose with phosphoric acid, made in the course of glucose metabolism by mammalian and other cells. It is a normal constituent of resting muscle and probably is in constant equilibrium with fructose-6-phosphate. (Stedman, 26th ed)
inositol 1,3-bisphosphate
myo-inositol 1,3,4,5,6-pentakisphosphate
Nalidixic AcidA synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA GYRASE.
inositol-1,3,4,6-tetrakisphosphatefor cpd without numerical locants of phosphate groups, index INOSITOL PHOSPHATES
inositol 1,3,4-trisphosphate
inositol-1,4,5,6-tetrakisphosphatefor cpd without numerical locants of phosphate groups, index INOSITOL PHOSPHATES
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