| Protein | Synonyms | Taxonomy |
|---|
| 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 | EC 3.1.4.11; Phosphoinositide phospholipase C-delta-1; Phospholipase C-III; PLC-III; Phospholipase C-delta-1; PLC-delta-1 | Homo sapiens (human) |
| Inositol-trisphosphate 3-kinase A | EC 2.7.1.127; Inositol 1,4,5-trisphosphate 3-kinase A; IP3 3-kinase A; IP3K A; InsP 3-kinase A | Homo sapiens (human) |
| Inositol polyphosphate multikinase | EC 2.7.1.140; EC 2.7.1.151; EC 2.7.1.153; Inositol 1,3,4,6-tetrakisphosphate 5-kinase | Homo sapiens (human) |
| 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | EC 3.1.4.11; PLC-148; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-II; PLC-II; Phospholipase C-gamma-1; PLC-gamma-1 | Homo sapiens (human) |
| 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 | EC 3.1.4.11; Phosphoinositide phospholipase C-gamma-2; Phospholipase C-IV; PLC-IV; Phospholipase C-gamma-2; PLC-gamma-2 | Homo sapiens (human) |
| Diphosphoinositol polyphosphate phosphohydrolase 1 | DIPP-1; EC 3.6.1.52; Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1; 3.6.1.-; Nucleoside diphosphate-linked moiety X motif 3; Nudix motif 3 | Homo sapiens (human) |
| Diphosphoinositol polyphosphate phosphohydrolase 3-beta | DIPP-3-beta; DIPP3-beta; hDIPP3beta; EC 3.6.1.52; Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 3-beta; Diadenosine hexaphosphate hydrolase (AMP-forming); 3.6.1.60; Nucleoside diphosphate-linked moiety X motif 11; Nudix motif 11; hAps1 | Homo sapiens (human) |
| Diphosphoinositol polyphosphate phosphohydrolase 2 | DIPP-2; EC 3.6.1.52; Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 2; Nucleoside diphosphate-linked moiety X motif 4; Nudix motif 4 | Homo sapiens (human) |
| Inositol-tetrakisphosphate 1-kinase | EC 2.7.1.134; Inositol 1,3,4-trisphosphate 5/6-kinase; Inositol-triphosphate 5/6-kinase; Ins(1,3,4)P(3) 5/6-kinase; 2.7.1.159 | Homo sapiens (human) |
| Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | EC 3.1.3.16; EC 3.1.3.48; EC 3.1.3.67; Mutated in multiple advanced cancers 1; Phosphatase and tensin homolog | Homo sapiens (human) |
| 5'-3' exonuclease PLD4 | EC 3.1.16.1; Choline phosphatase 4; Phosphatidylcholine-hydrolyzing phospholipase D4; Phospholipase D family member 4; Phospholipase D4; PLD 4 | Homo sapiens (human) |
| Calmodulin-1 | | Homo sapiens (human) |
| 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 | EC 3.1.4.11; PLC-154; Phosphoinositide phospholipase C-beta-1; Phospholipase C-I; PLC-I; Phospholipase C-beta-1; PLC-beta-1 | Homo sapiens (human) |
| Inositol-trisphosphate 3-kinase B | EC 2.7.1.127; Inositol 1,4,5-trisphosphate 3-kinase B; IP3 3-kinase B; IP3K B; InsP 3-kinase B | Homo sapiens (human) |
| Diphosphoinositol polyphosphate phosphohydrolase 3-alpha | DIPP-3-alpha; DIPP3-alpha; hDIPP3alpha; EC 3.6.1.52; Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 3-alpha; Diadenosine hexaphosphate hydrolase (AMP-forming); 3.6.1.60; Nucleoside diphosphate-linked moiety X motif 10; Nudix motif 10; hAps2 | Homo sapiens (human) |
| 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 | EC 3.1.4.11; Phosphoinositide phospholipase C-beta-2; Phospholipase C-beta-2; PLC-beta-2 | Homo sapiens (human) |
| Inositol oxygenase | EC 1.13.99.1; Aldehyde reductase-like 6; Kidney-specific protein 32; Myo-inositol oxygenase; MI oxygenase; Renal-specific oxidoreductase | Homo sapiens (human) |
| Myotubularin-related protein 7 | Inositol 1,3-bisphosphate phosphatase; 3.1.3.-; Phosphatidylinositol-3-phosphate phosphatase; 3.1.3.64 | Homo sapiens (human) |
| Inositol-pentakisphosphate 2-kinase | EC 2.7.1.158; IPK1 homolog; Inositol-1,3,4,5,6-pentakisphosphate 2-kinase; Ins(1,3,4,5,6)P5 2-kinase; InsP5 2-kinase | Homo sapiens (human) |
| 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 | EC 3.1.4.11; Phosphoinositide phospholipase C-eta-2; Phosphoinositide phospholipase C-like 4; PLC-L4; Phospholipase C-like protein 4; Phospholipase C-eta-2; PLC-eta2 | Homo sapiens (human) |
| 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 | hPLCD4; EC 3.1.4.11; Phosphoinositide phospholipase C-delta-4; Phospholipase C-delta-4; PLC-delta-4 | Homo sapiens (human) |
| Inositol polyphosphate 1-phosphatase | IPP; IPPase; EC 3.1.3.57 | Homo sapiens (human) |
| 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 | EC 3.1.4.11; Phosphoinositide phospholipase C-beta-4; Phospholipase C-beta-4; PLC-beta-4 | Homo sapiens (human) |
| 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 | EC 3.1.4.11; Pancreas-enriched phospholipase C; Phosphoinositide phospholipase C-epsilon-1; Phospholipase C-epsilon-1; PLC-epsilon-1 | Homo sapiens (human) |
| 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 | EC 3.1.4.11; Phosphoinositide phospholipase C-beta-3; Phospholipase C-beta-3; PLC-beta-3 | Homo sapiens (human) |
| 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 | EC 3.1.4.11; Phosphoinositide phospholipase C-eta-1; Phospholipase C-eta-1; PLC-eta-1; Phospholipase C-like protein 3; PLC-L3 | Homo sapiens (human) |
| 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 | EC 3.1.4.11; Phosphoinositide phospholipase C-zeta-1; Phospholipase C-zeta-1; PLC-zeta-1; Testis-development protein NYD-SP27 | Homo sapiens (human) |
| 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 | EC 3.1.4.11; Phosphoinositide phospholipase C-delta-3; Phospholipase C-delta-3; PLC-delta-3 | Homo sapiens (human) |
| Inositol-trisphosphate 3-kinase C | EC 2.7.1.127; Inositol 1,4,5-trisphosphate 3-kinase C; IP3 3-kinase C; IP3K C; InsP 3-kinase C | Homo sapiens (human) |
| Myotubularin-related protein 9 | Inactive phosphatidylinositol 3-phosphatase 9 | Homo sapiens (human) |
| Inositol-3-phosphate synthase 1 | IPS 1; EC 5.5.1.4; Myo-inositol 1-phosphate synthase; MI-1-P synthase; MIP synthase; hIPS; Myo-inositol 1-phosphate synthase A1; hINO1 | Homo sapiens (human) |
| Multiple inositol polyphosphate phosphatase 1 | EC 3.1.3.62; 2,3-bisphosphoglycerate 3-phosphatase; 2,3-BPG phosphatase; 3.1.3.80; Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase; Ins(1,3,4,5)P(4) 3-phosphatase | Homo sapiens (human) |
| Compound | Description |
|---|
| hydronium ion | |
| inositol 1-phosphate | |
| Calcium | A basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes. |
| iron | A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN. |
| Orthophosphate | |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| Magnesium | A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION. |
| inositol | An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| nad | A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed) |
| inositol 1,4,6-trisphosphate | inhibits (1,4,5)P3/(1,3,4,5)P4-polyphosphate 5-phosphatase; structure in first source |
| inositol 1,4-bis(phosphate) | induced in human platelets by thrombin; RN given refers to cpd without isomeric designation |
| inositol 4-phosphate | RN given refers to (DL-myo)-isomer |
| inositol 3-phosphate | RN given refers to (myo)-isomer |
| inositol 3,4-bisphosphate | RN given for (D)-isomer |
| adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| Glucose-6-Phosphate | An ester of glucose with phosphoric acid, made in the course of glucose metabolism by mammalian and other cells. It is a normal constituent of resting muscle and probably is in constant equilibrium with fructose-6-phosphate. (Stedman, 26th ed) |
| inositol 1,3-bisphosphate | |
| myo-inositol 1,3,4,5,6-pentakisphosphate | |
| Nalidixic Acid | A synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA GYRASE. |
| inositol-1,3,4,6-tetrakisphosphate | for cpd without numerical locants of phosphate groups, index INOSITOL PHOSPHATES |
| inositol 1,3,4-trisphosphate | |
| inositol-1,4,5,6-tetrakisphosphate | for cpd without numerical locants of phosphate groups, index INOSITOL PHOSPHATES |