Pathways > Inositol Metabolism
Page last updated: 2024-10-06

Inositol Metabolism

Proteins (22)

ProteinSynonymsTaxonomy
Inositol-trisphosphate 3-kinase AEC 2.7.1.127; Inositol 1,4,5-trisphosphate 3-kinase A; IP3 3-kinase A; IP3K A; InsP 3-kinase AHomo sapiens (human)
Beclin-1Coiled-coil myosin-like BCL2-interacting protein; Protein GT197Homo sapiens (human)
Inositol polyphosphate multikinaseEC 2.7.1.140; EC 2.7.1.151; EC 2.7.1.153; Inositol 1,3,4,6-tetrakisphosphate 5-kinaseHomo sapiens (human)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformPI3-kinase subunit alpha; PI3K-alpha; PI3Kalpha; PtdIns-3-kinase subunit alpha; EC 2.7.1.137; EC 2.7.1.153; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha; PtdIns-3-kinase subunit p110-alpha; p110alpha; Phosphoinositide 3-kHomo sapiens (human)
Phosphatidylinositol 3-kinase catalytic subunit type 3PI3-kinase type 3; PI3K type 3; PtdIns-3-kinase type 3; EC 2.7.1.137; Phosphatidylinositol 3-kinase p100 subunit; Phosphoinositide-3-kinase class 3; hVps34Homo sapiens (human)
1-phosphatidylinositol 3-phosphate 5-kinasePhosphatidylinositol 3-phosphate 5-kinase; EC 2.7.1.150; FYVE finger-containing phosphoinositide kinase; PIKfyve; Phosphatidylinositol 3-phosphate 5-kinase type III; PIPkin-III; Type III PIP kinase; Serine-protein kinase PIKFYVE; 2.7.11.1Homo sapiens (human)
Inositol-tetrakisphosphate 1-kinaseEC 2.7.1.134; Inositol 1,3,4-trisphosphate 5/6-kinase; Inositol-triphosphate 5/6-kinase; Ins(1,3,4)P(3) 5/6-kinase; 2.7.1.159Homo sapiens (human)
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1EC 3.1.3.27; PTEN-like phosphatase; Phosphoinositide lipid phosphatase; Protein-tyrosine phosphatase mitochondrial 1; 3.1.3.16; 3.1.3.48Homo sapiens (human)
Phosphoinositide 3-kinase regulatory subunit 4PI3-kinase regulatory subunit 4; EC 2.7.11.1; PI3-kinase p150 subunit; Phosphoinositide 3-kinase adaptor proteinHomo sapiens (human)
Phosphatidylinositol 4-kinase alphaPI4-kinase alpha; PI4K-alpha; PtdIns-4-kinase alpha; EC 2.7.1.67; Phosphatidylinositol 4-Kinase III alphaHomo sapiens (human)
Polyphosphoinositide phosphataseEC 3.1.3.-; Phosphatidylinositol 3,5-bisphosphate 5-phosphatase; SAC domain-containing protein 3Homo sapiens (human)
Inositol oxygenaseEC 1.13.99.1; Aldehyde reductase-like 6; Kidney-specific protein 32; Myo-inositol oxygenase; MI oxygenase; Renal-specific oxidoreductaseHomo sapiens (human)
Inositol-pentakisphosphate 2-kinaseEC 2.7.1.158; IPK1 homolog; Inositol-1,3,4,5,6-pentakisphosphate 2-kinase; Ins(1,3,4,5,6)P5 2-kinase; InsP5 2-kinaseHomo sapiens (human)
Inositol polyphosphate 1-phosphataseIPP; IPPase; EC 3.1.3.57Homo sapiens (human)
Inositol monophosphatase 1IMP 1; IMPase 1; EC 3.1.3.25; D-galactose 1-phosphate phosphatase; 3.1.3.94; Inositol-1(or 4)-monophosphatase 1; Lithium-sensitive myo-inositol monophosphatase A1Homo sapiens (human)
Protein VAC14 homologTax1-binding protein 2Homo sapiens (human)
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase AEC 3.1.3.56; Inositol polyphosphate 5-phosphatase JHomo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3EC 3.1.4.11; Phosphoinositide phospholipase C-delta-3; Phospholipase C-delta-3; PLC-delta-3Homo sapiens (human)
Inositol polyphosphate-4-phosphatase type I AInositol polyphosphate 4-phosphatase type I; Type I inositol 3,4-bisphosphate 4-phosphatase; 3.1.3.66Homo sapiens (human)
Activating molecule in BECN1-regulated autophagy protein 1Homo sapiens (human)
Inositol-3-phosphate synthase 1IPS 1; EC 5.5.1.4; Myo-inositol 1-phosphate synthase; MI-1-P synthase; MIP synthase; hIPS; Myo-inositol 1-phosphate synthase A1; hINO1Homo sapiens (human)
Multiple inositol polyphosphate phosphatase 1EC 3.1.3.62; 2,3-bisphosphoglycerate 3-phosphatase; 2,3-BPG phosphatase; 3.1.3.80; Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase; Ins(1,3,4,5)P(4) 3-phosphataseHomo sapiens (human)

Compounds (21)

CompoundDescription
phosphoric acidconcise etchant is 37% H3PO4
Orthophosphate
inositol-1,3,4,5,6-pentakisphosphateinvolved in signal transduction
Adenosine TriphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
phytic acidComplexing agent for removal of traces of heavy metal ions. It acts also as a hypocalcemic agent.
inositolAn isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
phosphatidylinositol 3,4,5-triphosphate
inositol 1,4-bis(phosphate)induced in human platelets by thrombin; RN given refers to cpd without isomeric designation
inositol 1,3,4-trisphosphate
inositol 1,4,5-trisphosphateIntracellular messenger formed by the action of phospholipase C on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make up the cell membrane. Inositol 1,4,5-trisphosphate is released into the cytoplasm where it releases calcium ions from internal stores within the cell's endoplasmic reticulum. These calcium ions stimulate the activity of B kinase or calmodulin.
inositol 3-phosphateRN given refers to (myo)-isomer
inositol 3,4-bisphosphateRN given for (D)-isomer
Glucose-6-PhosphateAn ester of glucose with phosphoric acid, made in the course of glucose metabolism by mammalian and other cells. It is a normal constituent of resting muscle and probably is in constant equilibrium with fructose-6-phosphate. (Stedman, 26th ed)
inositol-1,3,4,5-tetrakisphosphatefor cpd without numerical locants of phosphate groups, index INOSITOL PHOSPHATES
inositol-3,4,5,6-tetrakisphosphatefor cpd without numerical locants of phosphate groups, index INOSITOL PHOSPHATES
inositol-1,3,4,6-tetrakisphosphatefor cpd without numerical locants of phosphate groups, index INOSITOL PHOSPHATES
inositol-1,4,5,6-tetrakisphosphatefor cpd without numerical locants of phosphate groups, index INOSITOL PHOSPHATES
pyrophosphate
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