Page last updated: 2024-10-06

Innate Immune System

Proteins (407)

ProteinSynonymsTaxonomy
Apolipoprotein B-100Apo B-100Homo sapiens (human)
Complement factor HH factor 1Homo sapiens (human)
Interferon-inducible protein AIM2Absent in melanoma 2Homo sapiens (human)
NucleoproteinN; Nucleocapsid protein; NC; Protein NSevere acute respiratory syndrome coronavirus 2
Neutrophil cytosol factor 1NCF-1; 47 kDa autosomal chronic granulomatous disease protein; 47 kDa neutrophil oxidase factor; NCF-47K; Neutrophil NADPH oxidase factor 1; Nox organizer 2; Nox-organizing protein 2; SH3 and PX domain-containing protein 1A; p47-phoxHomo sapiens (human)
NEDD8-conjugating enzyme Ubc12EC 2.3.2.34; NEDD8 carrier protein; Ubiquitin-conjugating enzyme E2 MHomo sapiens (human)
Actin-related protein 3Actin-like protein 3Homo sapiens (human)
Neutrophil gelatinase-associated lipocalinNGAL; 25 kDa alpha-2-microglobulin-related subunit of MMP-9; Lipocalin-2; Oncogene 24p3; Siderocalin; p25Homo sapiens (human)
Lymphocyte cytosolic protein 2SH2 domain-containing leukocyte protein of 76 kDa; SLP-76 tyrosine phosphoprotein; SLP76Homo sapiens (human)
Toll-like receptor 1EC 3.2.2.6; Toll/interleukin-1 receptor-like protein; TILHomo sapiens (human)
Mitochondrial antiviral-signaling proteinMAVS; CARD adapter inducing interferon beta; Cardif; Interferon beta promoter stimulator protein 1; IPS-1; Putative NF-kappa-B-activating protein 031N; Virus-induced-signaling adapter; VISAHomo sapiens (human)
NLR family CARD domain-containing protein 4CARD, LRR, and NACHT-containing protein; Clan protein; Caspase recruitment domain-containing protein 12; Ice protease-activating factor; IpafHomo sapiens (human)
Three-prime repair exonuclease 1EC 3.1.11.2; 3'-5' exonuclease TREX1; Deoxyribonuclease III; DNase IIIHomo sapiens (human)
Mucosa-associated lymphoid tissue lymphoma translocation protein 1EC 3.4.22.-; MALT lymphoma-associated translocation; ParacaspaseHomo sapiens (human)
Inhibitor of nuclear factor kappa-B kinase subunit betaI-kappa-B-kinase beta; IKK-B; IKK-beta; IkBKB; EC 2.7.11.10; I-kappa-B kinase 2; IKK2; Nuclear factor NF-kappa-B inhibitor kinase beta; NFKBIKB; Serine/threonine protein kinase IKBKB; 2.7.11.1Homo sapiens (human)
Inhibitor of nuclear factor kappa-B kinase subunit alphaI-kappa-B kinase alpha; IKK-A; IKK-alpha; IkBKA; IkappaB kinase; EC 2.7.11.10; Conserved helix-loop-helix ubiquitous kinase; I-kappa-B kinase 1; IKK1; Nuclear factor NF-kappa-B inhibitor kinase alpha; NFKBIKA; Transcription factor 16; TCF-16Homo sapiens (human)
3-phosphoinositide-dependent protein kinase 1hPDK1; EC 2.7.11.1Homo sapiens (human)
Receptor-interacting serine/threonine-protein kinase 2EC 2.7.11.1; CARD-containing interleukin-1 beta-converting enzyme-associated kinase; CARD-containing IL-1 beta ICE-kinase; RIP-like-interacting CLARP kinase; Receptor-interacting protein 2; RIP-2; Tyrosine-protein kinase RIPK2; 2.7.10.2Homo sapiens (human)
Ribosomal protein S6 kinase alpha-5S6K-alpha-5; EC 2.7.11.1; 90 kDa ribosomal protein S6 kinase 5; Nuclear mitogen- and stress-activated protein kinase 1; RSK-like protein kinase; RSKLHomo sapiens (human)
Tyrosine-protein kinase ABL1EC 2.7.10.2; Abelson murine leukemia viral oncogene homolog 1; Abelson tyrosine-protein kinase 1; Proto-oncogene c-Abl; p150Homo sapiens (human)
RAF proto-oncogene serine/threonine-protein kinaseEC 2.7.11.1; Proto-oncogene c-RAF; cRaf; Raf-1Homo sapiens (human)
Cellular tumor antigen p53Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53Homo sapiens (human)
Heat shock protein HSP 90-alphaEC 3.6.4.10; Heat shock 86 kDa; HSP 86; HSP86; Lipopolysaccharide-associated protein 2; LAP-2; LPS-associated protein 2; Renal carcinoma antigen NY-REN-38Homo sapiens (human)
Tyrosine-protein kinase LynEC 2.7.10.2; Lck/Yes-related novel protein tyrosine kinase; V-yes-1 Yamaguchi sarcoma viral related oncogene homolog; p53Lyn; p56LynHomo sapiens (human)
Heat shock protein HSP 90-betaHSP 90; Heat shock 84 kDa; HSP 84; HSP84Homo sapiens (human)
NF-kappa-B inhibitor alphaI-kappa-B-alpha; IkB-alpha; IkappaBalpha; Major histocompatibility complex enhancer-binding protein MAD3Homo sapiens (human)
Mitogen-activated protein kinase 3 MAP kinase 3; MAPK 3; EC 2.7.11.24; ERT2; Extracellular signal-regulated kinase 1; ERK-1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p44-ERK1Homo sapiens (human)
Proteasome subunit beta type-9EC 3.4.25.1; Low molecular mass protein 2; Macropain chain 7; Multicatalytic endopeptidase complex chain 7; Proteasome chain 7; Proteasome subunit beta-1i; Really interesting new gene 12 proteinHomo sapiens (human)
Mitogen-activated protein kinase 1MAP kinase 1; MAPK 1; EC 2.7.11.24; ERT1; Extracellular signal-regulated kinase 2; ERK-2; MAP kinase isoform p42; p42-MAPK; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK 2Homo sapiens (human)
Mitogen-activated protein kinase kinase kinase 8EC 2.7.11.25; Cancer Osaka thyroid oncogene; Proto-oncogene c-Cot; Serine/threonine-protein kinase cot; Tumor progression locus 2; TPL-2Homo sapiens (human)
Tyrosine-protein kinase SYKEC 2.7.10.2; Spleen tyrosine kinase; p72-SykHomo sapiens (human)
MAP kinase-activated protein kinase 2MAPK-activated protein kinase 2; MAPKAP kinase 2; MAPKAP-K2; MAPKAPK-2; MK-2; MK2; EC 2.7.11.1Homo sapiens (human)
C-C chemokine receptor type 6C-C CKR-6; CC-CKR-6; CCR-6; Chemokine receptor-like 3; CKR-L3; DRY6; G-protein coupled receptor 29; GPR-CY4; GPRCY4; LARC receptorHomo sapiens (human)
Dual specificity mitogen-activated protein kinase kinase 6MAP kinase kinase 6; MAPKK 6; EC 2.7.12.2; MAPK/ERK kinase 6; MEK 6; Stress-activated protein kinase kinase 3; SAPK kinase 3; SAPKK-3; SAPKK3Homo sapiens (human)
Transcription factor p65Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3Homo sapiens (human)
Protein kinase C theta typeEC 2.7.11.13; nPKC-thetaHomo sapiens (human)
Tyrosine-protein phosphatase non-receptor type 11EC 3.1.3.48; Protein-tyrosine phosphatase 1D; PTP-1D; Protein-tyrosine phosphatase 2C; PTP-2C; SH-PTP2; SHP-2; Shp2; SH-PTP3Homo sapiens (human)
Tyrosine-protein kinase BTKEC 2.7.10.2; Agammaglobulinemia tyrosine kinase; ATK; B-cell progenitor kinase; BPK; Bruton tyrosine kinaseHomo sapiens (human)
Serine/threonine-protein kinase PAK 1EC 2.7.11.1; Alpha-PAK; p21-activated kinase 1; PAK-1; p65-PAKHomo sapiens (human)
Mitogen-activated protein kinase kinase kinase 1EC 2.7.11.25; MAPK/ERK kinase kinase 1; MEK kinase 1; MEKK 1Homo sapiens (human)
Baculoviral IAP repeat-containing protein 3EC 2.3.2.27; Apoptosis inhibitor 2; API2; Cellular inhibitor of apoptosis 2; C-IAP2; IAP homolog C; Inhibitor of apoptosis protein 1; hIAP-1; hIAP1; RING finger protein 49; RING-type E3 ubiquitin transferase BIRC3; TNFR2-TRAF-signaling complex protein 1Homo sapiens (human)
Caspase-8CASP-8; EC 3.4.22.61; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; MACHHomo sapiens (human)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1Mitogen-activated protein kinase kinase kinase 7-interacting protein 1; TGF-beta-activated kinase 1-binding protein 1; TAK1-binding protein 1Homo sapiens (human)
Phosphatidylinositol 3-kinase catalytic subunit type 3PI3-kinase type 3; PI3K type 3; PtdIns-3-kinase type 3; EC 2.7.1.137; Phosphatidylinositol 3-kinase p100 subunit; Phosphoinositide-3-kinase class 3; hVps34Homo sapiens (human)
Toll-like receptor 8Homo sapiens (human)
Toll-like receptor 7Homo sapiens (human)
Integrin alpha-MCD11 antigen-like family member B; CR-3 alpha chain; Cell surface glycoprotein MAC-1 subunit alpha; Leukocyte adhesion receptor MO1; Neutrophil adherence receptorHomo sapiens (human)
Tyrosine-protein phosphatase non-receptor type 4EC 3.1.3.48; Protein-tyrosine phosphatase MEG1; MEG; PTPase-MEG1Homo sapiens (human)
HLA class I histocompatibility antigen, B alpha chain Human leukocyte antigen B; HLA-BHomo sapiens (human)
Complement decay-accelerating factorHomo sapiens (human)
Calcineurin subunit B type 1Protein phosphatase 2B regulatory subunit 1; Protein phosphatase 3 regulatory subunit B alpha isoform 1Homo sapiens (human)
DermcidinEC 3.4.-.-; PreproteolysinHomo sapiens (human)
Interferon regulatory factor 3IRF-3Homo sapiens (human)
Tumor necrosis factor alpha-induced protein 3TNF alpha-induced protein 3; EC 2.3.2.-; EC 3.4.19.12; OTU domain-containing protein 7C; Putative DNA-binding protein A20; Zinc finger protein A20Homo sapiens (human)
Beta-2-microglobulinHomo sapiens (human)
Transcription factor RelBI-RelHomo sapiens (human)
Dedicator of cytokinesis protein 1180 kDa protein downstream of CRK; DOCK180Homo sapiens (human)
TRAF family member-associated NF-kappa-B activatorTRAF-interacting protein; I-TRAFHomo sapiens (human)
Interferon-induced helicase C domain-containing protein 1EC 3.6.4.13; Clinically amyopathic dermatomyositis autoantigen 140 kDa; CADM-140 autoantigen; Helicase with 2 CARD domains; Helicard; Interferon-induced with helicase C domain protein 1; Melanoma differentiation-associated protein 5; MDA-5; Murabutide dowHomo sapiens (human)
Ubiquitin carboxyl-terminal hydrolase CYLDEC 3.4.19.12; Deubiquitinating enzyme CYLD; Ubiquitin thioesterase CYLD; Ubiquitin-specific-processing protease CYLDHomo sapiens (human)
Complement C1s subcomponentEC 3.4.21.42; C1 esterase; Complement component 1 subcomponent sHomo sapiens (human)
Low affinity immunoglobulin gamma Fc region receptor II-aIgG Fc receptor II-a; CDw32; Fc-gamma RII-a; Fc-gamma-RIIa; FcRII-aHomo sapiens (human)
Ras-related C3 botulinum toxin substrate 2GX; Small G protein; p21-Rac2Homo sapiens (human)
Double-strand break repair protein MRE11EC 3.1.-.-; Double-strand break repair protein MRE11A; Meiotic recombination 11 homolog 1; MRE11 homolog 1; Meiotic recombination 11 homolog A; MRE11 homolog AHomo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1EC 3.1.4.11; PLC-148; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-II; PLC-II; Phospholipase C-gamma-1; PLC-gamma-1Homo sapiens (human)
Mitogen-activated protein kinase kinase kinase 7EC 2.7.11.25; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1Homo sapiens (human)
Integrin beta-2Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; Complement receptor C3 subunit betaHomo sapiens (human)
Transcription factor AP-1Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39Homo sapiens (human)
Heme oxygenase 1HO-1; EC 1.14.14.18Homo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2EC 3.1.4.11; Phosphoinositide phospholipase C-gamma-2; Phospholipase C-IV; PLC-IV; Phospholipase C-gamma-2; PLC-gamma-2Homo sapiens (human)
Proteasome subunit beta type-1Macropain subunit C5; Multicatalytic endopeptidase complex subunit C5; Proteasome component C5; Proteasome gamma chainHomo sapiens (human)
MyeloblastinEC 3.4.21.76; AGP7; C-ANCA antigen; Leukocyte proteinase 3; PR-3; PR3; Neutrophil proteinase 4; NP-4; P29; Wegener autoantigenHomo sapiens (human)
Caspase-1CASP-1; EC 3.4.22.36; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45Homo sapiens (human)
C-C chemokine receptor type 2C-C CKR-2; CC-CKR-2; CCR-2; CCR2; Monocyte chemoattractant protein 1 receptor; MCP-1-RHomo sapiens (human)
LIM domain kinase 1LIMK-1; EC 2.7.11.1Homo sapiens (human)
Cell division control protein 42 homologEC 3.6.5.2; G25K GTP-binding proteinHomo sapiens (human)
DNA-dependent protein kinase catalytic subunitDNA-PK catalytic subunit; DNA-PKcs; EC 2.7.11.1; DNPK1; p460Homo sapiens (human)
Protein kinase C delta typeEC 2.7.11.13; Tyrosine-protein kinase PRKCD; 2.7.10.2; nPKC-deltaHomo sapiens (human)
Mitogen-activated protein kinase 7MAP kinase 7; MAPK 7; EC 2.7.11.24; Big MAP kinase 1; BMK-1; Extracellular signal-regulated kinase 5; ERK-5Homo sapiens (human)
Receptor-interacting serine/threonine-protein kinase 1EC 2.7.11.1; Cell death protein RIP; Receptor-interacting protein 1; RIP-1Homo sapiens (human)
Mitogen-activated protein kinase kinase kinase 14EC 2.7.11.25; NF-kappa-beta-inducing kinase; HsNIK; Serine/threonine-protein kinase NIKHomo sapiens (human)
P2X purinoceptor 7P2X7; ATP receptor; P2Z receptor; Purinergic receptorHomo sapiens (human)
Triggering receptor expressed on myeloid cells 1TREM-1; Triggering receptor expressed on monocytes 1Homo sapiens (human)
Toll-like receptor 9Homo sapiens (human)
Interleukin-1 receptor-associated kinase 4IRAK-4; EC 2.7.11.1; Renal carcinoma antigen NY-REN-64Homo sapiens (human)
Serine/threonine-protein kinase TBK1EC 2.7.11.1; NF-kappa-B-activating kinase; T2K; TANK-binding kinase 1Homo sapiens (human)
Nucleotide-binding oligomerization domain-containing protein 1Caspase recruitment domain-containing protein 4Homo sapiens (human)
Actin-related protein 2/3 complex subunit 5Arp2/3 complex 16 kDa subunit; p16-ARCHomo sapiens (human)
Stimulator of interferon genes proteinhSTING; Endoplasmic reticulum interferon stimulator; ERIS; Mediator of IRF3 activation; hMITA; Transmembrane protein 173Homo sapiens (human)
Cyclic GMP-AMP synthasecGAMP synthase; cGAS; h-cGAS; EC 2.7.7.86; 2'3'-cGAMP synthase; Mab-21 domain-containing protein 1Homo sapiens (human)
Interferon betaIFN-beta; Fibroblast interferonHomo sapiens (human)
Complement C2EC 3.4.21.43; C3/C5 convertaseHomo sapiens (human)
Neutrophil defensin 1Defensin, alpha 1; HNP-1; HP-1; HP1Homo sapiens (human)
S-adenosylhomocysteine hydrolase-like protein 1DC-expressed AHCY-like molecule; IP(3)Rs binding protein released with IP(3); IRBIT; Putative adenosylhomocysteinase 2; S-adenosyl-L-homocysteine hydrolase 2; AdoHcyase 2Homo sapiens (human)
Proteasome activator complex subunit 311S regulator complex subunit gamma; REG-gamma; Activator of multicatalytic protease subunit 3; Ki nuclear autoantigen; Proteasome activator 28 subunit gamma; PA28g; PA28gammaHomo sapiens (human)
Cullin-1CUL-1Homo sapiens (human)
Pannexin-1Homo sapiens (human)
E3 ubiquitin-protein ligase Itchy homologItch; EC 2.3.2.26; Atrophin-1-interacting protein 4; AIP4; HECT-type E3 ubiquitin transferase Itchy homolog; NFE2-associated polypeptide 1; NAPP1Homo sapiens (human)
Cyclic AMP-dependent transcription factor ATF-1cAMP-dependent transcription factor ATF-1; Activating transcription factor 1; Protein TREB36Homo sapiens (human)
85/88 kDa calcium-independent phospholipase A2CaI-PLA2; EC 3.1.1.4; 2-lysophosphatidylcholine acylhydrolase; 3.1.1.5; Group VI phospholipase A2; GVI PLA2; Intracellular membrane-associated calcium-independent phospholipase A2 beta; iPLA2-beta; Palmitoyl-CoA hydrolase; 3.1.2.2; Patatin-like phospholipHomo sapiens (human)
Complement factor BEC 3.4.21.47; C3/C5 convertase; Glycine-rich beta glycoprotein; GBG; PBF2; Properdin factor BHomo sapiens (human)
High affinity immunoglobulin epsilon receptor subunit alphaFc-epsilon RI-alpha; FcERI; IgE Fc receptor subunit alphaHomo sapiens (human)
Cyclic AMP-responsive element-binding protein 1CREB-1; cAMP-responsive element-binding protein 1Homo sapiens (human)
Platelet glycoprotein 4Fatty acid translocase; FAT; Glycoprotein IIIb; GPIIIB; Leukocyte differentiation antigen CD36; PAS IV; PAS-4; Platelet collagen receptor; Platelet glycoprotein IV; GPIV; Thrombospondin receptorHomo sapiens (human)
Nuclear factor NF-kappa-B p105 subunitDNA-binding factor KBF1; EBP-1; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1Homo sapiens (human)
LactoperoxidaseLPO; EC 1.11.1.7; Salivary peroxidase; SPOHomo sapiens (human)
Cofilin-118 kDa phosphoprotein; p18; Cofilin, non-muscle isoformHomo sapiens (human)
Adapter molecule crkProto-oncogene c-Crk; p38Homo sapiens (human)
Proteasome subunit beta type-3Proteasome chain 13; Proteasome component C10-II; Proteasome theta chainHomo sapiens (human)
Ras-related C3 botulinum toxin substrate 1EC 3.6.5.2; Cell migration-inducing gene 5 protein; Ras-like protein TC25; p21-Rac1Homo sapiens (human)
Myeloid differentiation primary response protein MyD88Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 1026S proteasome regulatory subunit p28; Gankyrin; p28(GANK)Homo sapiens (human)
T-cell surface glycoprotein CD4T-cell surface antigen T4/Leu-3Homo sapiens (human)
ATP-dependent DNA/RNA helicase DHX36EC 3.6.4.12; EC 3.6.4.13; DEAD/H box polypeptide 36; DEAH-box protein 36; G4-resolvase-1; G4R1; MLE-like protein 1; RNA helicase associated with AU-rich element proteinHomo sapiens (human)
Regenerating islet-derived protein 3-alphaREG-3-alpha; Hepatointestinal pancreatic protein; HIP/PAP; Human proislet peptide; Pancreatitis-associated protein 1; Regenerating islet-derived protein III-alpha; Reg III-alphaHomo sapiens (human)
Ubiquitin carboxyl-terminal hydrolase 14EC 3.4.19.12; Deubiquitinating enzyme 14; Ubiquitin thioesterase 14; Ubiquitin-specific-processing protease 14Homo sapiens (human)
Son of sevenless homolog 1SOS-1Homo sapiens (human)
C-type lectin domain family 6 member AC-type lectin superfamily member 10; Dendritic cell-associated C-type lectin 2; DC-associated C-type lectin 2; Dectin-2Homo sapiens (human)
NEDD8-activating enzyme E1 catalytic subunitEC 6.2.1.64; NEDD8-activating enzyme E1C; Ubiquitin-activating enzyme E1C; Ubiquitin-like modifier-activating enzyme 3; Ubiquitin-activating enzyme 3Homo sapiens (human)
C-type lectin domain family 4 member CBlood dendritic cell antigen 2; BDCA-2; C-type lectin superfamily member 7; Dendritic lectinHomo sapiens (human)
Phosphoinositide 3-kinase regulatory subunit 4PI3-kinase regulatory subunit 4; EC 2.7.11.1; PI3-kinase p150 subunit; Phosphoinositide 3-kinase adaptor proteinHomo sapiens (human)
Receptor-interacting serine/threonine-protein kinase 3EC 2.7.11.1; RIP-like protein kinase 3; Receptor-interacting protein 3; RIP-3Homo sapiens (human)
NF-kappa-B essential modulatorNEMO; FIP-3; IkB kinase-associated protein 1; IKKAP1; Inhibitor of nuclear factor kappa-B kinase subunit gamma; I-kappa-B kinase subunit gamma; IKK-gamma; IKKG; IkB kinase subunit gamma; NF-kappa-B essential modifierHomo sapiens (human)
NACHT, LRR and PYD domains-containing protein 3 Angiotensin/vasopressin receptor AII/AVP-like; Caterpiller protein 1.1; CLR1.1; Cold-induced autoinflammatory syndrome 1 protein; Cryopyrin; PYRIN-containing APAF1-like protein 1Homo sapiens (human)
Complement C5C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4Homo sapiens (human)
LactotransferrinLactoferrin; EC 3.4.21.-; Growth-inhibiting protein 12; TalalactoferrinHomo sapiens (human)
Protein S100-A9Calgranulin-B; Calprotectin L1H subunit; Leukocyte L1 complex heavy chain; Migration inhibitory factor-related protein 14; MRP-14; p14; S100 calcium-binding protein A9Homo sapiens (human)
Gasdermin-DGasdermin domain-containing protein 1Homo sapiens (human)
C5a anaphylatoxin chemotactic receptor 2Complement component 5a receptor 2; G-protein coupled receptor 77Homo sapiens (human)
Toll-like receptor 4EC 3.2.2.6; hTollHomo sapiens (human)
Dual specificity mitogen-activated protein kinase kinase 7MAP kinase kinase 7; MAPKK 7; EC 2.7.12.2; JNK-activating kinase 2; MAPK/ERK kinase 7; MEK 7; Stress-activated protein kinase kinase 4; SAPK kinase 4; SAPKK-4; SAPKK4; c-Jun N-terminal kinase kinase 2; JNK kinase 2; JNKK 2Homo sapiens (human)
Toll-like receptor 3Homo sapiens (human)
Toll-like receptor 2EC 3.2.2.6; Toll/interleukin-1 receptor-like protein 4Homo sapiens (human)
Complement C1r subcomponentEC 3.4.21.41; Complement component 1 subcomponent rHomo sapiens (human)
Interleukin-1 betaIL-1 beta; CatabolinHomo sapiens (human)
Protein S100-BS-100 protein beta chain; S-100 protein subunit beta; S100 calcium-binding protein BHomo sapiens (human)
Envelope glycoprotein gp160Env polyproteinHIV-1 M:B_HXB2R
MyeloperoxidaseMPO; EC 1.11.2.2Homo sapiens (human)
Monocyte differentiation antigen CD14Myeloid cell-specific leucine-rich glycoproteinHomo sapiens (human)
High mobility group protein B1High mobility group protein 1; HMG-1Homo sapiens (human)
Calmodulin-1Homo sapiens (human)
ThioredoxinTrx; ATL-derived factor; ADF; Surface-associated sulphydryl protein; SASPHomo sapiens (human)
High affinity immunoglobulin gamma Fc receptor IIgG Fc receptor I; Fc-gamma RI; FcRI; Fc-gamma RIA; FcgammaRIaHomo sapiens (human)
Phospholipase A2, membrane associatedEC 3.1.1.4; GIIC sPLA2; Group IIA phospholipase A2; Non-pancreatic secretory phospholipase A2; NPS-PLA2; Phosphatidylcholine 2-acylhydrolase 2AHomo sapiens (human)
C5a anaphylatoxin chemotactic receptor 1C5a anaphylatoxin chemotactic receptor; C5a-R; C5aRHomo sapiens (human)
Proteasome subunit beta type-8EC 3.4.25.1; Low molecular mass protein 7; Macropain subunit C13; Multicatalytic endopeptidase complex subunit C13; Proteasome component C13; Proteasome subunit beta-5i; Really interesting new gene 10 proteinHomo sapiens (human)
Proteasome subunit beta type-5EC 3.4.25.1; Macropain epsilon chain; Multicatalytic endopeptidase complex epsilon chain; Proteasome chain 6; Proteasome epsilon chain; Proteasome subunit MB1; Proteasome subunit XHomo sapiens (human)
Catenin beta-1Beta-cateninHomo sapiens (human)
Signal transducer and activator of transcription 6IL-4 StatHomo sapiens (human)
Dual specificity mitogen-activated protein kinase kinase 4MAP kinase kinase 4; MAPKK 4; EC 2.7.12.2; JNK-activating kinase 1; MAPK/ERK kinase 4; MEK 4; SAPK/ERK kinase 1; SEK1; Stress-activated protein kinase kinase 1; SAPK kinase 1; SAPKK-1; SAPKK1; c-Jun N-terminal kinase kinase 1; JNKKHomo sapiens (human)
Natural resistance-associated macrophage protein 1NRAMP 1; Solute carrier family 11 member 1Homo sapiens (human)
Proteasome subunit beta type-2Macropain subunit C7-I; Multicatalytic endopeptidase complex subunit C7-I; Proteasome component C7-IHomo sapiens (human)
Dual specificity protein phosphatase 3EC 3.1.3.16; EC 3.1.3.48; Dual specificity protein phosphatase VHR; Vaccinia H1-related phosphatase; VHRHomo sapiens (human)
Interleukin-1 receptor-associated kinase 1IRAK-1; EC 2.7.11.1Homo sapiens (human)
CD81 antigen26 kDa cell surface protein TAPA-1; Target of the antiproliferative antibody 1; Tetraspanin-28; Tspan-28Homo sapiens (human)
Ubiquitin-conjugating enzyme E2 NEC 2.3.2.23; Bendless-like ubiquitin-conjugating enzyme; E2 ubiquitin-conjugating enzyme N; Ubc13; UbcH13; Ubiquitin carrier protein N; Ubiquitin-protein ligase NHomo sapiens (human)
Serine/threonine-protein kinase PAK 2EC 2.7.11.1; Gamma-PAK; PAK65; S6/H4 kinase; p21-activated kinase 2; PAK-2; p58Homo sapiens (human)
Ubiquitin-conjugating enzyme E2 variant 1UEV-1; CROC-1; TRAF6-regulated IKK activator 1 beta Uev1AHomo sapiens (human)
Baculoviral IAP repeat-containing protein 2EC 2.3.2.27; Cellular inhibitor of apoptosis 1; C-IAP1; IAP homolog B; Inhibitor of apoptosis protein 2; hIAP-2; hIAP2; RING finger protein 48; RING-type E3 ubiquitin transferase BIRC2; TNFR2-TRAF-signaling complex protein 2Homo sapiens (human)
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1EC 5.2.1.8; Peptidyl-prolyl cis-trans isomerase Pin1; PPIase Pin1; Rotamase Pin1Homo sapiens (human)
C3a anaphylatoxin chemotactic receptorC3AR; C3a-RHomo sapiens (human)
CREB-binding proteinHistone lysine acetyltransferase CREBBP; 2.3.1.48; Protein-lysine acetyltransferase CREBBP; 2.3.1.-Homo sapiens (human)
Caspase-10CASP-10; EC 3.4.22.63; Apoptotic protease Mch-4; FAS-associated death domain protein interleukin-1B-converting enzyme 2; FLICE2; ICE-like apoptotic protease 4Homo sapiens (human)
C-type lectin domain family 7 member ABeta-glucan receptor; C-type lectin superfamily member 12; Dendritic cell-associated C-type lectin 1; DC-associated C-type lectin 1; Dectin-1Homo sapiens (human)
Nucleotide-binding oligomerization domain-containing protein 2Caspase recruitment domain-containing protein 15; Inflammatory bowel disease protein 1Homo sapiens (human)
CD209 antigenC-type lectin domain family 4 member L; Dendritic cell-specific ICAM-3-grabbing non-integrin 1; DC-SIGN; DC-SIGN1Homo sapiens (human)
Interleukin-1 receptor-associated kinase 3IRAK-3; EC 2.7.11.1; IL-1 receptor-associated kinase M; IRAK-MHomo sapiens (human)
Lymphocyte antigen 96Ly-96; ESOP-1; Protein MD-2Homo sapiens (human)
Complement C3C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1Homo sapiens (human)
GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1EC 2.4.2.31; ADP-ribosyltransferase C2 and C3 toxin-like 1; ARTC1; Mono(ADP-ribosyl)transferase 1Homo sapiens (human)
Actin-related protein 2/3 complex subunit 1BArp2/3 complex 41 kDa subunit; p41-ARCHomo sapiens (human)
Leucine-rich repeat flightless-interacting protein 1LRR FLII-interacting protein 1; GC-binding factor 2; TAR RNA-interacting proteinHomo sapiens (human)
Ubiquitin-like protein ATG12Autophagy-related protein 12; APG12-likeHomo sapiens (human)
C4b-binding protein alpha chainC4bp; Proline-rich protein; PRPHomo sapiens (human)
Non-structural protein 1NS1; Non-structural protein 1CHuman respiratory syncytial virus A2
Cyclic AMP-dependent transcription factor ATF-2cAMP-dependent transcription factor ATF-2; Activating transcription factor 2; Cyclic AMP-responsive element-binding protein 2; CREB-2; cAMP-responsive element-binding protein 2; HB16; cAMP response element-binding protein CRE-BP1Homo sapiens (human)
Membrane cofactor proteinTLX; Trophoblast leukocyte common antigenHomo sapiens (human)
Bactericidal permeability-increasing proteinBPI; CAP 57Homo sapiens (human)
FAS-associated death domain proteinFAS-associating death domain-containing protein; Growth-inhibiting gene 3 protein; Mediator of receptor induced toxicity; Protein FADDHomo sapiens (human)
Membrane proteinM; E1 glycoprotein; Matrix glycoprotein; Membrane glycoproteinSevere acute respiratory syndrome coronavirus 2
Copper-transporting ATPase 1EC 7.2.2.8; Copper pump 1; Menkes disease-associated proteinHomo sapiens (human)
Proteasome subunit beta type-11EC 3.4.25.1; Proteasome subunit beta-5tHomo sapiens (human)
26S proteasome non-ATPase regulatory subunit 1126S proteasome regulatory subunit RPN6; 26S proteasome regulatory subunit S9; 26S proteasome regulatory subunit p44.5Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 1226S proteasome regulatory subunit RPN5; 26S proteasome regulatory subunit p55Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 14EC 3.4.19.-; 26S proteasome regulatory subunit RPN11; 26S proteasome-associated PAD1 homolog 1Homo sapiens (human)
Proteasome subunit alpha type-7Proteasome subunit RC6-1; Proteasome subunit XAPC7Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 326S proteasome regulatory subunit RPN3; 26S proteasome regulatory subunit S3; Proteasome subunit p58Homo sapiens (human)
Toll-like receptor 5Toll/interleukin-1 receptor-like protein 3Homo sapiens (human)
Proto-oncogene c-FosCellular oncogene fos; G0/G1 switch regulatory protein 7Homo sapiens (human)
Endoplasmin94 kDa glucose-regulated protein; GRP-94; Heat shock protein 90 kDa beta member 1; Tumor rejection antigen 1; gp96 homologHomo sapiens (human)
26S proteasome regulatory subunit 6A26S proteasome AAA-ATPase subunit RPT5; Proteasome 26S subunit ATPase 3; Proteasome subunit P50; Tat-binding protein 1; TBP-1Homo sapiens (human)
ETS domain-containing protein Elk-1Homo sapiens (human)
Proteasome subunit alpha type-130 kDa prosomal protein; PROS-30; Macropain subunit C2; Multicatalytic endopeptidase complex subunit C2; Proteasome component C2; Proteasome nu chainHomo sapiens (human)
Proteasome subunit alpha type-2Macropain subunit C3; Multicatalytic endopeptidase complex subunit C3; Proteasome component C3Homo sapiens (human)
Proteasome subunit alpha type-3Macropain subunit C8; Multicatalytic endopeptidase complex subunit C8; Proteasome component C8Homo sapiens (human)
Proteasome subunit alpha type-4Macropain subunit C9; Multicatalytic endopeptidase complex subunit C9; Proteasome component C9; Proteasome subunit LHomo sapiens (human)
Proteasome subunit alpha type-5Macropain zeta chain; Multicatalytic endopeptidase complex zeta chain; Proteasome zeta chainHomo sapiens (human)
Proteasome subunit beta type-426 kDa prosomal protein; HsBPROS26; PROS-26; Macropain beta chain; Multicatalytic endopeptidase complex beta chain; Proteasome beta chain; Proteasome chain 3; HsN3Homo sapiens (human)
Proteasome subunit beta type-6EC 3.4.25.1; Macropain delta chain; Multicatalytic endopeptidase complex delta chain; Proteasome delta chain; Proteasome subunit YHomo sapiens (human)
26S proteasome regulatory subunit 726S proteasome AAA-ATPase subunit RPT1; Proteasome 26S subunit ATPase 2; Protein MSS1Homo sapiens (human)
Proteasome subunit beta type-10EC 3.4.25.1; Low molecular mass protein 10; Macropain subunit MECl-1; Multicatalytic endopeptidase complex subunit MECl-1; Proteasome MECl-1; Proteasome subunit beta-2iHomo sapiens (human)
26S proteasome regulatory subunit 6B26S proteasome AAA-ATPase subunit RPT3; MB67-interacting protein; MIP224; Proteasome 26S subunit ATPase 4; Tat-binding protein 7; TBP-7Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 826S proteasome regulatory subunit RPN12; 26S proteasome regulatory subunit S14; p31Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 726S proteasome regulatory subunit RPN8; 26S proteasome regulatory subunit S12; Mov34 protein homolog; Proteasome subunit p40Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 426S proteasome regulatory subunit RPN10; 26S proteasome regulatory subunit S5A; Antisecretory factor 1; AF; ASF; Multiubiquitin chain-binding proteinHomo sapiens (human)
26S proteasome complex subunit SEM126S proteasome complex subunit DSS1; Deleted in split hand/split foot protein 1; Split hand/foot deleted protein 1; Split hand/foot malformation type 1 proteinHomo sapiens (human)
Proteasome subunit alpha type-627 kDa prosomal protein; PROS-27; p27K; Macropain iota chain; Multicatalytic endopeptidase complex iota chain; Proteasome iota chainHomo sapiens (human)
26S proteasome regulatory subunit 4P26s4; 26S proteasome AAA-ATPase subunit RPT2; Proteasome 26S subunit ATPase 1Homo sapiens (human)
26S proteasome regulatory subunit 826S proteasome AAA-ATPase subunit RPT6; Proteasome 26S subunit ATPase 5; Proteasome subunit p45; Thyroid hormone receptor-interacting protein 1; TRIP1; p45/SUGHomo sapiens (human)
26S proteasome regulatory subunit 10B26S proteasome AAA-ATPase subunit RPT4; Proteasome 26S subunit ATPase 6; Proteasome subunit p42Homo sapiens (human)
Nuclear factor NF-kappa-B p100 subunit DNA-binding factor KBF2; H2TF1; Lymphocyte translocation chromosome 10 protein; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2; Oncogene Lyt-10; Lyt10Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 226S proteasome regulatory subunit RPN1; 26S proteasome regulatory subunit S2; 26S proteasome subunit p97; Protein 55.11; Tumor necrosis factor type 1 receptor-associated protein 2Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 626S proteasome regulatory subunit RPN7; 26S proteasome regulatory subunit S10; Breast cancer-associated protein SGA-113M; Phosphonoformate immuno-associated protein 4; Proteasome regulatory particle subunit p44S10; p42AHomo sapiens (human)
Advanced glycosylation end product-specific receptorReceptor for advanced glycosylation end productsHomo sapiens (human)
Proteasome subunit alpha-type 8Proteasome alpha 4 subunit; Alpha4s; Proteasome subunit alpha-type 7-likeHomo sapiens (human)
Proteasome subunit beta type-7EC 3.4.25.1; Macropain chain Z; Multicatalytic endopeptidase complex chain Z; Proteasome subunit ZHomo sapiens (human)
26S proteasome non-ATPase regulatory subunit 126S proteasome regulatory subunit RPN2; 26S proteasome regulatory subunit S1; 26S proteasome subunit p112Homo sapiens (human)
Ubl carboxyl-terminal hydrolase 18 EC 3.4.19.-; 43 kDa ISG15-specific protease; hUBP43; ISG15-specific-processing protease; Ubl thioesterase 18Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 1326S proteasome regulatory subunit RPN9; 26S proteasome regulatory subunit S11; 26S proteasome regulatory subunit p40.5Homo sapiens (human)
Toll-like receptor 6EC 3.2.2.6Homo sapiens (human)
Actin-related protein 2/3 complex subunit 2Arp2/3 complex 34 kDa subunit; p34-ARCHomo sapiens (human)
X-ray repair cross-complementing protein 6EC 3.6.4.-; EC 4.2.99.-; 5'-deoxyribose-5-phosphate lyase Ku70; 5'-dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; CTC box-binding factor 75 kDa subunit; CTC75; CTCBF; DNAHomo sapiens (human)
Mannan-binding lectin serine protease 1EC 3.4.21.-; Complement factor MASP-3; Complement-activating component of Ra-reactive factor; Mannose-binding lectin-associated serine protease 1; MASP-1; Mannose-binding protein-associated serine protease; Ra-reactive factor serine protease p100; RaRF; SHomo sapiens (human)
S-phase kinase-associated protein 1Cyclin-A/CDK2-associated protein p19; p19A; Organ of Corti protein 2; OCP-2; Organ of Corti protein II; OCP-II; RNA polymerase II elongation factor-like protein; SIII; Transcription elongation factor B polypeptide 1-like; p19skp1Homo sapiens (human)
Proteasome activator complex subunit 111S regulator complex subunit alpha; REG-alpha; Activator of multicatalytic protease subunit 1; Interferon gamma up-regulated I-5111 protein; IGUP I-5111; Proteasome activator 28 subunit alpha; PA28a; PA28alphaHomo sapiens (human)
Poly(rC)-binding protein 2Alpha-CP2; Heterogeneous nuclear ribonucleoprotein E2; hnRNP E2Homo sapiens (human)
Protein BRICK1BRK1Homo sapiens (human)
Proteasome activator complex subunit 211S regulator complex subunit beta; REG-beta; Activator of multicatalytic protease subunit 2; Proteasome activator 28 subunit beta; PA28b; PA28betaHomo sapiens (human)
Apoptosis-associated speck-like protein containing a CARDhASC; Caspase recruitment domain-containing protein 5; PYD and CARD domain-containing protein; Target of methylation-induced silencing 1Homo sapiens (human)
Triggering receptor expressed on myeloid cells 2TREM-2; Triggering receptor expressed on monocytes 2Homo sapiens (human)
Peptidoglycan recognition protein 1Peptidoglycan recognition protein short; PGRP-SHomo sapiens (human)
VitronectinVN; S-protein; Serum-spreading factor; V75Homo sapiens (human)
Actin-related protein 2Actin-like protein 2Homo sapiens (human)
Interleukin-1 receptor-associated kinase-like 2IRAK-2Homo sapiens (human)
Complement component C9Homo sapiens (human)
X-ray repair cross-complementing protein 5EC 3.6.4.-; 86 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 2; ATP-dependent DNA helicase II 80 kDa subunit; CTC box-binding factor 85 kDa subunit; CTC85; CTCBF; DNA repair protein XRCC5; Ku80; Ku86; Lupus Ku autoantigen protein p86; NuHomo sapiens (human)
Inactive serine/threonine-protein kinase VRK3Serine/threonine-protein pseudokinase VRK3; Vaccinia-related kinase 3Homo sapiens (human)
C-type lectin domain family 4 member EC-type lectin superfamily member 9; Macrophage-inducible C-type lectin; MINCLEHomo sapiens (human)
TNF receptor-associated factor 6EC 2.3.2.27; E3 ubiquitin-protein ligase TRAF6; Interleukin-1 signal transducer; RING finger protein 85; RING-type E3 ubiquitin transferase TRAF6Homo sapiens (human)
NACHT, LRR and PYD domains-containing protein 4Cancer/testis antigen 58; CT58; PAAD and NACHT-containing protein 2; PAN2; PYRIN and NACHT-containing protein 2; PYRIN-containing APAF1-like protein 4; PYPAF4; Ribonuclease inhibitor 2Homo sapiens (human)
PyrinMarenostrinHomo sapiens (human)
HLA class I histocompatibility antigen, C alpha chain HLA-C; HLA-Cw; Human leukocyte antigen CHomo sapiens (human)
Lipopolysaccharide-binding proteinLBPHomo sapiens (human)
TNF receptor-associated factor 3EC 2.3.2.27; CAP-1; CD40 receptor-associated factor 1; CRAF1; CD40-binding protein; CD40BP; LMP1-associated protein 1; LAP1; RING-type E3 ubiquitin transferase TRAF3Homo sapiens (human)
Antiviral innate immune response receptor RIG-IDEAD box protein 58; Probable ATP-dependent RNA helicase DDX58; 3.6.4.13; RIG-I-like receptor 1; RLR-1; Retinoic acid-inducible gene 1 protein; RIG-1; Retinoic acid-inducible gene I protein; RIG-IHomo sapiens (human)
Complement component C7Homo sapiens (human)
Early endosome antigen 1Endosome-associated protein p162; Zinc finger FYVE domain-containing protein 2Homo sapiens (human)
Complement C4-BBasic complement C4; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3Homo sapiens (human)
High affinity immunoglobulin epsilon receptor subunit betaFcERI; Fc epsilon receptor I beta-chain; IgE Fc receptor subunit beta; Membrane-spanning 4-domains subfamily A member 2Homo sapiens (human)
Natural cytotoxicity triggering receptor 2Lymphocyte antigen 95 homolog; NK cell-activating receptor; Natural killer cell p44-related protein; NK-p44; NKp44Homo sapiens (human)
FlagellinEscherichia coli K-12
Complement factor IEC 3.4.21.45; C3B/C4B inactivatorHomo sapiens (human)
Complement component C8 alpha chainComplement component 8 subunit alphaHomo sapiens (human)
Complement component C8 beta chainComplement component 8 subunit betaHomo sapiens (human)
ClusterinAging-associated gene 4 protein; Apolipoprotein J; Apo-J; Complement cytolysis inhibitor; CLI; Complement-associated protein SP-40,40; Ku70-binding protein 1; NA1/NA2; Sulfated glycoprotein 2; SGP-2; Testosterone-repressed prostate message 2; TRPM-2Homo sapiens (human)
Complement component C6Homo sapiens (human)
Complement receptor type 2Cr2; Complement C3d receptor; Epstein-Barr virus receptor; EBV receptorHomo sapiens (human)
Lysozyme CEC 3.2.1.17; 1,4-beta-N-acetylmuramidase CHomo sapiens (human)
N-acetylmuramoyl-L-alanine amidaseEC 3.5.1.28; Peptidoglycan recognition protein 2; Peptidoglycan recognition protein long; PGRP-LHomo sapiens (human)
Suppressor of cytokine signaling 1SOCS-1; JAK-binding protein; JAB; STAT-induced STAT inhibitor 1; SSI-1; Tec-interacting protein 3; TIP-3Homo sapiens (human)
TIR domain-containing adapter molecule 1TICAM-1; Proline-rich, vinculin and TIR domain-containing protein B; Putative NF-kappa-B-activating protein 502H; Toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta; MyD88-3; TIR domain-containing adapter protein induciHomo sapiens (human)
Z-DNA-binding protein 1DNA-dependent activator of IFN-regulatory factors; DAI; Tumor stroma and activated macrophage protein DLM-1Homo sapiens (human)
Vitamin K-dependent protein SHomo sapiens (human)
Actin-related protein 2/3 complex subunit 1ASOP2-like proteinHomo sapiens (human)
26S proteasome non-ATPase regulatory subunit 926S proteasome regulatory subunit p27Homo sapiens (human)
NEDD4-binding protein 1N4BP1; EC 3.1.-.-Homo sapiens (human)
High affinity immunoglobulin epsilon receptor subunit gammaFc receptor gamma-chain; FcRgamma; Fc-epsilon RI-gamma; IgE Fc receptor subunit gamma; FceRI gammaHomo sapiens (human)
Toll-like receptor 10EC 3.2.2.6Homo sapiens (human)
NKG2-D type II integral membrane proteinKiller cell lectin-like receptor subfamily K member 1; NK cell receptor D; NKG2-D-activating NK receptorHomo sapiens (human)
OTU domain-containing protein 5EC 3.4.19.12; Deubiquitinating enzyme A; DUBAHomo sapiens (human)
Lymphocyte antigen 86Ly-86; Protein MD-1Homo sapiens (human)
TYRO protein tyrosine kinase-binding proteinDNAX-activation protein 12; Killer-activating receptor-associated protein; KAR-associated proteinHomo sapiens (human)
Protein NLRC5Caterpiller protein 16.1; CLR16.1; Nucleotide-binding oligomerization domain protein 27; Nucleotide-binding oligomerization domain protein 4Homo sapiens (human)
DNA-directed RNA polymerases I, II, and III subunit RPABC4RNA polymerases I, II, and III subunit ABC4; ABC10-alpha; DNA-directed RNA polymerase II subunit K; RNA polymerase II 7.0 kDa subunit; RPB7.0; RPB10alphaHomo sapiens (human)
GRB2-associated-binding protein 2GRB2-associated binder 2; Growth factor receptor bound protein 2-associated protein 2; pp100Homo sapiens (human)
Thioredoxin-interacting proteinThioredoxin-binding protein 2; Vitamin D3 up-regulated protein 1Homo sapiens (human)
Plasma protease C1 inhibitorC1 Inh; C1Inh; C1 esterase inhibitor; C1-inhibiting factor; Serpin G1Homo sapiens (human)
C-type lectin domain family 10 member AC-type lectin superfamily member 14; Macrophage lectin 2Homo sapiens (human)
Proline-serine-threonine phosphatase-interacting protein 1PEST phosphatase-interacting protein 1; CD2-binding protein 1; H-PIPHomo sapiens (human)
Caspase recruitment domain-containing protein 9hCARD9Homo sapiens (human)
CMRF35-like molecule 7CLM-7; CD300 antigen-like family member B; CMRF35-A2; Immune receptor expressed on myeloid cells 3; IREM-3; Leukocyte mono-Ig-like receptor 5; Triggering receptor expressed on myeloid cells 5; TREM-5Homo sapiens (human)
Signal-regulatory protein beta-1SIRP-beta-1; CD172 antigen-like family member BHomo sapiens (human)
Copper transport protein ATOX1Metal transport protein ATX1Homo sapiens (human)
DNA-directed RNA polymerase III subunit RPC1RNA polymerase III subunit C1; EC 2.7.7.6; DNA-directed RNA polymerase III largest subunit; DNA-directed RNA polymerase III subunit A; RNA polymerase III 155 kDa subunit; RPC155; RNA polymerase III subunit C160Homo sapiens (human)
Actin-related protein 2/3 complex subunit 3Arp2/3 complex 21 kDa subunit; p21-ARCHomo sapiens (human)
DNA-directed RNA polymerases I and III subunit RPAC1DNA-directed RNA polymerase I subunit C; RNA polymerases I and III subunit AC1; AC40; DNA-directed RNA polymerases I and III 40 kDa polypeptide; RPA40; RPA39; RPC40Homo sapiens (human)
Gasdermin-EInversely correlated with estrogen receptor expression 1; ICERE-1; Non-syndromic hearing impairment protein 5Homo sapiens (human)
DNA-directed RNA polymerase III subunit RPC9RNA polymerase III subunit C9; Calcitonin gene-related peptide-receptor component protein; CGRP-RCP; CGRP-receptor component protein; CGRPRCP; HsC17Homo sapiens (human)
GRB2-related adapter protein 2Adapter protein GRID; GRB-2-like protein; GRB2L; GRBLG; GRBX; Grf40 adapter protein; Grf-40; Growth factor receptor-binding protein; Hematopoietic cell-associated adapter protein GrpL; P38; Protein GADS; SH3-SH2-SH3 adapter MonaHomo sapiens (human)
Mitochondrial import receptor subunit TOM70Mitochondrial precursor proteins import receptor; Translocase of outer membrane 70 kDa subunit; Translocase of outer mitochondrial membrane protein 70Homo sapiens (human)
EppinCancer/testis antigen 71; CT71; Epididymal protease inhibitor; Protease inhibitor WAP7; Serine protease inhibitor-like with Kunitz and WAP domains 1; WAP four-disulfide core domain protein 7Homo sapiens (human)
B-cell lymphoma/leukemia 10B-cell CLL/lymphoma 10; Bcl-10; CARD-containing molecule enhancing NF-kappa-B; CARD-like apoptotic protein; hCLAP; CED-3/ICH-1 prodomain homologous E10-like regulator; CIPER; Cellular homolog of vCARMEN; cCARMEN; Cellular-E10; c-E10; Mammalian CARD-contaiHomo sapiens (human)
Immunoglobulin heavy constant epsilonIg epsilon chain C region; Ig epsilon chain C region NDHomo sapiens (human)
Complement C1q subcomponent subunit AHomo sapiens (human)
Complement C1q subcomponent subunit BHomo sapiens (human)
Complement C1q subcomponent subunit CHomo sapiens (human)
Semenogelin-1Cancer/testis antigen 103; Semenogelin I; SGIHomo sapiens (human)
Protein S100-A8Calgranulin-A; Calprotectin L1L subunit; Cystic fibrosis antigen; CFAG; Leukocyte L1 complex light chain; Migration inhibitory factor-related protein 8; MRP-8; p8; S100 calcium-binding protein A8; Urinary stone protein band AHomo sapiens (human)
Ubiquitin-like protein ISG15Interferon-induced 15 kDa protein; Interferon-induced 17 kDa protein; IP17; Ubiquitin cross-reactive protein; hUCRPHomo sapiens (human)
DNA-directed RNA polymerase III subunit RPC4RNA polymerase III subunit C4; DNA-directed RNA polymerase III subunit D; Protein BN51; RNA polymerase III 47 kDa subunit; RPC53 homologHomo sapiens (human)
Complement component C8 gamma chainHomo sapiens (human)
Low affinity immunoglobulin gamma Fc region receptor III-ACD16a antigen; Fc-gamma RIII-alpha; Fc-gamma RIII; Fc-gamma RIIIa; FcRIII; FcRIIIa; FcR-10; IgG Fc receptor III-2Homo sapiens (human)
T-cell surface glycoprotein CD3 gamma chainT-cell receptor T3 gamma chainHomo sapiens (human)
Complement C4-AAcidic complement C4; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2Homo sapiens (human)
Neutrophil defensin 4Defensin, alpha 4; HNP-4; HP-4Homo sapiens (human)
Intercellular adhesion molecule 2ICAM-2Homo sapiens (human)
HLA class I histocompatibility antigen, alpha chain EMHC class I antigen EHomo sapiens (human)
CD59 glycoprotein1F5 antigen; 20 kDa homologous restriction factor; HRF-20; HRF20; MAC-inhibitory protein; MAC-IP; MEM43 antigen; Membrane attack complex inhibition factor; MACIF; Membrane inhibitor of reactive lysis; MIRL; ProtectinHomo sapiens (human)
B-lymphocyte antigen CD19B-lymphocyte surface antigen B4; Differentiation antigen CD19; T-cell surface antigen Leu-12Homo sapiens (human)
Complement receptor type 1C3b/C4b receptorHomo sapiens (human)
DNA-directed RNA polymerases I, II, and III subunit RPABC1RNA polymerases I, II, and III subunit ABC1; DNA-directed RNA polymerase II 23 kDa polypeptide; DNA-directed RNA polymerase II subunit E; RPB5 homolog; XAP4Homo sapiens (human)
E3 ubiquitin-protein ligase TRIM21EC 2.3.2.27; 52 kDa Ro protein; 52 kDa ribonucleoprotein autoantigen Ro/SS-A; RING finger protein 81; RING-type E3 ubiquitin transferase TRIM21; Ro(SS-A); Sjoegren syndrome type A antigen; SS-A; Tripartite motif-containing protein 21Homo sapiens (human)
Neutrophil cytosol factor 2NCF-2; 67 kDa neutrophil oxidase factor; NADPH oxidase activator 2; Neutrophil NADPH oxidase factor 2; p67-phoxHomo sapiens (human)
C4b-binding protein beta chainHomo sapiens (human)
GranulysinLymphokine LAG-2; Protein NKG5; T-cell activation protein 519Homo sapiens (human)
Protein S100-A1S-100 protein alpha chain; S-100 protein subunit alpha; S100 calcium-binding protein A1Homo sapiens (human)
NKG2-C type II integral membrane proteinCD159 antigen-like family member C; NK cell receptor C; NKG2-C-activating NK receptorHomo sapiens (human)
Intercellular adhesion molecule 3ICAM-3; CDw50; ICAM-RHomo sapiens (human)
MerlinMoesin-ezrin-radixin-like protein; Neurofibromin-2; Schwannomerlin; SchwannominHomo sapiens (human)
Complement factor H-related protein 2FHR-2; DDESK59; H factor-like 3; H factor-like protein 2Homo sapiens (human)
Killer cell immunoglobulin-like receptor 2DS2CD158 antigen-like family member J; MHC class I NK cell receptor; NK receptor 183 ActI; Natural killer-associated transcript 5; NKAT-5; p58 natural killer cell receptor clone CL-49; p58 NK receptor CL-49Homo sapiens (human)
Killer cell immunoglobulin-like receptor 2DS4CD158 antigen-like family member I; MHC class I NK cell receptor; Natural killer-associated transcript 8; NKAT-8; P58 natural killer cell receptor clones CL-39/CL-17; p58 NK receptor CL-39/CL-17Homo sapiens (human)
Cathelicidin antimicrobial peptide18 kDa cationic antimicrobial protein; CAP-18; hCAP-18Homo sapiens (human)
DNA-directed RNA polymerases I, II, and III subunit RPABC3RNA polymerases I, II, and III subunit ABC3; DNA-directed RNA polymerase II subunit H; DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide; RPB17; RPB8 homolog; hRPB8Homo sapiens (human)
Nck-associated protein 1-likeHematopoietic protein 1; Membrane-associated protein HEM-1Homo sapiens (human)
Toll/interleukin-1 receptor domain-containing adapter proteinTIR domain-containing adapter protein; Adaptor protein Wyatt; MyD88 adapter-like protein; MyD88-2Homo sapiens (human)
Neutrophil defensin 3Defensin, alpha 3; HNP-3; HP-3; HP3Homo sapiens (human)
Actin-related protein 2/3 complex subunit 4Arp2/3 complex 20 kDa subunit; p20-ARCHomo sapiens (human)
DNA-directed RNA polymerases I, II, and III subunit RPABC2RNA polymerases I, II, and III subunit ABC2; DNA-directed RNA polymerase II subunit F; DNA-directed RNA polymerases I, II, and III 14.4 kDa polypeptide; RPABC14.4; RPB14.4; RPB6 homolog; RPC15Homo sapiens (human)
DNA-directed RNA polymerases I, II, and III subunit RPABC5RNA polymerases I, II, and III subunit ABC5; DNA-directed RNA polymerase III subunit L; RNA polymerase II 7.6 kDa subunit; RPB7.6; RPB10 homologHomo sapiens (human)
Beta-defensin 103Beta-defensin 3; BD-3; DEFB-3; HBD3; hBD-3; Defensin, beta 103; Defensin-like proteinHomo sapiens (human)
Defensin-5Defensin, alpha 5; HD5(20-94)Homo sapiens (human)
Defensin-6Defensin, alpha 6Homo sapiens (human)
Complement factor H-related protein 3FHR-3; DOWN16; H factor-like protein 3Homo sapiens (human)
Complement factor H-related protein 1FHR-1; H factor-like protein 1; H-factor-like 1; H36Homo sapiens (human)
ATP-dependent RNA helicase AEC 3.6.4.13; DEAH box protein 9; DExH-box helicase 9; Leukophysin; LKP; Nuclear DNA helicase II; NDH II; RNA helicase AHomo sapiens (human)
Natural killer cells antigen CD94KP43; Killer cell lectin-like receptor subfamily D member 1; NK cell receptorHomo sapiens (human)
Angio-associated migratory cell proteinHomo sapiens (human)
E3 ubiquitin/ISG15 ligase TRIM25EC 6.3.2.n3; Estrogen-responsive finger protein; RING finger protein 147; RING-type E3 ubiquitin transferase; 2.3.2.27; RING-type E3 ubiquitin transferase TRIM25; Tripartite motif-containing protein 25; Ubiquitin/ISG15-conjugating enzyme TRIM25; Zinc fingHomo sapiens (human)
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoformPP2A B subunit isoform B'-delta; PP2A B subunit isoform B56-delta; PP2A B subunit isoform PR61-delta; PP2A B subunit isoform R5-deltaHomo sapiens (human)
Killer cell immunoglobulin-like receptor 3DS1MHC class I NK cell receptor; Natural killer-associated transcript 10; NKAT-10Homo sapiens (human)
Killer cell immunoglobulin-like receptor 2DS5CD158 antigen-like family member G; MHC class I NK cell receptor; Natural killer-associated transcript 9; NKAT-9Homo sapiens (human)
Proteasome activator complex subunit 4Proteasome activator PA200Homo sapiens (human)
Leucine-rich repeat-containing protein 14Homo sapiens (human)
Neutrophil cytosol factor 4 NCF-4; Neutrophil NADPH oxidase factor 4; SH3 and PX domain-containing protein 4; p40-phox; p40phoxHomo sapiens (human)
26S proteasome non-ATPase regulatory subunit 526S protease subunit S5 basic; 26S proteasome subunit S5BHomo sapiens (human)
Gamma-interferon-inducible protein 16Ifi-16; Interferon-inducible myeloid differentiation transcriptional activatorHomo sapiens (human)
V-type proton ATPase subunit FV-ATPase subunit F; V-ATPase 14 kDa subunit; Vacuolar proton pump subunit FHomo sapiens (human)
Triokinase/FMN cyclaseBifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing)Homo sapiens (human)
CMRF35-like molecule 2CLM-2; CD300 antigen-like family member E; CMRF35-A5; Immune receptor expressed on myeloid cells 2; IREM-2; Polymeric immunoglobulin receptor 2; PIgR-2; PIgR2; Poly-Ig receptor 2Homo sapiens (human)
PDZ domain-containing protein 11ATPase-interacting PDZ protein; Plasma membrane calcium ATPase-interacting single-PDZ protein; PMCA-interacting single-PDZ proteinHomo sapiens (human)
Single Ig IL-1-related receptorSingle Ig IL-1R-related molecule; Single immunoglobulin domain-containing IL1R-related protein; Toll/interleukin-1 receptor 8; TIR8Homo sapiens (human)
Inhibitor of nuclear factor kappa-B kinase-interacting proteinI kappa-B kinase-interacting protein; IKBKB-interacting protein; IKK-interacting proteinHomo sapiens (human)
NLR family CARD domain-containing protein 3CARD15-like protein; Caterpiller protein 16.2; CLR16.2; NACHT, LRR and CARD domains-containing protein 3; Nucleotide-binding oligomerization domain protein 3Homo sapiens (human)
NLR family member X1Caterpiller protein 11.3; CLR11.3; Nucleotide-binding oligomerization domain protein 26; Nucleotide-binding oligomerization domain protein 5; Nucleotide-binding oligomerization domain protein 9Homo sapiens (human)
Tax1-binding protein 1TRAF6-binding proteinHomo sapiens (human)
TIR domain-containing adapter molecule 2TICAM-2; Putative NF-kappa-B-activating protein 502; TRIF-related adapter molecule; Toll-like receptor adaptor protein 3; Toll/interleukin-1 receptor domain-containing protein; MyD88-4Homo sapiens (human)
TNFAIP3-interacting protein 2 A20-binding inhibitor of NF-kappa-B activation 2; ABIN-2; Fetal liver LKB1-interacting proteinHomo sapiens (human)
Intelectin-1ITLN-1; Endothelial lectin HL-1; Galactofuranose-binding lectin; Intestinal lactoferrin receptor; OmentinHomo sapiens (human)
C-type lectin domain family 4 member DC-type lectin superfamily member 8; C-type lectin-like receptor 6; CLEC-6Homo sapiens (human)
Complement factor H-related protein 4FHR-4Homo sapiens (human)
Proteasome inhibitor PI31 subunithPI31Homo sapiens (human)
Interferon regulatory factor 7IRF-7Homo sapiens (human)
Liver-expressed antimicrobial peptide 2LEAP-2Homo sapiens (human)
Probable ATP-dependent RNA helicase DHX58EC 3.6.4.13; Probable ATP-dependent helicase LGP2; Protein D11Lgp2 homolog; RIG-I-like receptor 3; RLR-3; RIG-I-like receptor LGP2; RLRHomo sapiens (human)
TRAF-interacting protein with FHA domain-containing protein APutative MAPK-activating protein PM14; Putative NF-kappa-B-activating protein 20; TRAF2-binding proteinHomo sapiens (human)
Voltage-gated hydrogen channel 1Hydrogen voltage-gated channel 1; HV1; Voltage sensor domain-only proteinHomo sapiens (human)
E3 ubiquitin-protein ligase RNF125EC 2.3.2.27; RING finger protein 125; T-cell RING activation protein 1; TRAC-1Homo sapiens (human)
Peptidoglycan recognition protein 4Peptidoglycan recognition protein I-beta; PGLYRPIbeta; PGRP-I-beta; Peptidoglycan recognition protein intermediate betaHomo sapiens (human)
Peptidoglycan recognition protein 3Peptidoglycan recognition protein I-alpha; PGLYRPIalpha; PGRP-I-alpha; Peptidoglycan recognition protein intermediate alphaHomo sapiens (human)
Alpha-protein kinase 1EC 2.7.11.1; Chromosome 4 kinase; Lymphocyte alpha-protein kinaseHomo sapiens (human)
V-type proton ATPase 21 kDa proteolipid subunitV-ATPase 21 kDa proteolipid subunit; Vacuolar proton pump 21 kDa proteolipid subunit; hATPLHomo sapiens (human)
CD180 antigenLymphocyte antigen 64; Radioprotective 105 kDa proteinHomo sapiens (human)
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrialProtein SITPECHomo sapiens (human)
Suppressor of IKBKE 1Suppressor of IKK-epsilonHomo sapiens (human)
Protein canopy homolog 3CTG repeat protein 4a; Expanded repeat-domain protein CAG/CTG 5; Protein associated with TLR4; Trinucleotide repeat-containing gene 5 proteinHomo sapiens (human)
DNA-directed RNA polymerase III subunit RPC3RNA polymerase III subunit C3; DNA-directed RNA polymerase III subunit C; RNA polymerase III 62 kDa subunit; RPC62Homo sapiens (human)
Collectin-11Collectin kidney protein 1; CL-K1Homo sapiens (human)
Caspase recruitment domain-containing protein 11CARD-containing MAGUK protein 1; Carma 1Homo sapiens (human)
Complement factor H-related protein 5FHR-5Homo sapiens (human)
NACHT, LRR and PYD domains-containing protein 1EC 3.6.4.-; Caspase recruitment domain-containing protein 7; Death effector filament-forming ced-4-like apoptosis protein; Nucleotide-binding domain and caspase recruitment domainHomo sapiens (human)
Linker for activation of T-cells family member 2Linker for activation of B-cells; Membrane-associated adapter molecule; Non-T-cell activation linker; Williams-Beuren syndrome chromosomal region 15 protein; Williams-Beuren syndrome chromosomal region 5 proteinHomo sapiens (human)
Protein unc-93 homolog B1Unc-93B1; hUNC93B1Homo sapiens (human)
DNA-directed RNA polymerase III subunit RPC6RNA polymerase III subunit C6; DNA-directed RNA polymerase III subunit F; RNA polymerase III 39 kDa subunit; RPC39Homo sapiens (human)
Rabenosyn-5110 kDa protein; FYVE finger-containing Rab5 effector protein rabenosyn-5; RAB effector RBSN; Zinc finger FYVE domain-containing protein 20Homo sapiens (human)
Autophagy protein 5APG5-like; Apoptosis-specific proteinHomo sapiens (human)
Unconventional myosin-XUnconventional myosin-10Homo sapiens (human)
DNA-directed RNA polymerase III subunit RPC5RNA polymerase III subunit C5; DNA-directed RNA polymerase III 80 kDa polypeptideHomo sapiens (human)
DNA-directed RNA polymerase III subunit RPC2RNA polymerase III subunit C2; EC 2.7.7.6; C128; DNA-directed RNA polymerase III 127.6 kDa polypeptide; DNA-directed RNA polymerase III subunit BHomo sapiens (human)
E3 ubiquitin-protein ligase RNF216EC 2.3.2.27; RING finger protein 216; RING-type E3 ubiquitin transferase RNF216; Triad domain-containing protein 3; Ubiquitin-conjugating enzyme 7-interacting protein 1; Zinc finger protein inhibiting NF-kappa-BHomo sapiens (human)
C-type lectin domain family 5 member AC-type lectin superfamily member 5; Myeloid DAP12-associating lectin 1; MDL-1Homo sapiens (human)
V-type proton ATPase subunit HV-ATPase subunit H; Nef-binding protein 1; NBP1; Protein VMA13 homolog; V-ATPase 50/57 kDa subunits; Vacuolar proton pump subunit H; Vacuolar proton pump subunit SFDHomo sapiens (human)
E3 ISG15--protein ligase HERC5EC 2.3.2.-; Cyclin-E-binding protein 1; HECT domain and RCC1-like domain-containing protein 5Homo sapiens (human)
Probable ATP-dependent RNA helicase DDX41EC 3.6.4.13; DEAD box protein 41; DEAD box protein abstrakt homologHomo sapiens (human)
F-box/WD repeat-containing protein 11F-box and WD repeats protein beta-TrCP2; F-box/WD repeat-containing protein 1B; Homologous to Slimb protein; HOSHomo sapiens (human)
C-type lectin domain family 4 member AC-type lectin DDB27; C-type lectin superfamily member 6; Dendritic cell immunoreceptor; Lectin-like immunoreceptorHomo sapiens (human)
Brain-specific angiogenesis inhibitor 1-associated protein 2BAI-associated protein 2; BAI1-associated protein 2; Protein BAP2; Fas ligand-associated factor 3; FLAF3; Insulin receptor substrate p53/p58; IRS-58; IRSp53/58; Insulin receptor substrate protein of 53 kDa; IRSp53; Insulin receptor substrate p53Homo sapiens (human)
F-box/WD repeat-containing protein 1AE3RSIkappaB; Epididymis tissue protein Li 2a; F-box and WD repeats protein beta-TrCP; pIkappaBalpha-E3 receptor subunitHomo sapiens (human)
Nck-associated protein 1NAP 1; Membrane-associated protein HEM-2; p125Nap1Homo sapiens (human)
E3 ubiquitin-protein ligase DTX4EC 2.3.2.27; Protein deltex-4; Deltex4; RING finger protein 155; RING-type E3 ubiquitin transferase DTX4Homo sapiens (human)
DNA-directed RNA polymerase III subunit RPC10RNA polymerase III subunit C10; DNA-directed RNA polymerase III subunit K; RNA polymerase III 12.5 kDa subunit; RPC12.5; RNA polymerase III subunit C11; HsC11p; RPC11; hRPC11Homo sapiens (human)
Protein SGT1 homologProtein 40-6-3; Sgt1; Suppressor of G2 allele of SKP1 homologHomo sapiens (human)
DNA-directed RNA polymerase III subunit RPC8RNA polymerase III subunit C8; DNA-directed RNA polymerase III subunit H; RNA polymerase III subunit 22.9 kDa subunit; RPC22.9Homo sapiens (human)
V-type proton ATPase subunit DV-ATPase subunit D; V-ATPase 28 kDa accessory protein; Vacuolar proton pump subunit DHomo sapiens (human)
Collectin-10Collectin liver protein 1; CL-L1; Collectin-34; CL-34Homo sapiens (human)
Protein POLR1D, isoform 2Homo sapiens (human)
ORF9b proteinORF9b; Accessory protein 9b; ORF-9b; Protein 9bSevere acute respiratory syndrome coronavirus 2

Compounds (61)

CompoundDescription
hydronium ion
copperA heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55.
Nitric OxideA free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
ArginineAn essential amino acid that is physiologically active in the L-form.
carbonatesSalts or ions of the theoretical carbonic acid, containing the radical CO2(3-). Carbonates are readily decomposed by acids. The carbonates of the alkali metals are water-soluble; all others are insoluble. (From Grant & Hackh's Chemical Dictionary, 5th ed)
nitrous acidNitrous acid (HNO2). A weak acid that exists only in solution. It can form water-soluble nitrites and stable esters. (From Merck Index, 11th ed)
CalciumA basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
ironA metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
ManganeseA trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
IronA metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
cholineA basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.
chlorineAn element with atomic symbol Cl, atomic number 17, and atomic weight 35, and member of the halogen family.
ZincA metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
Orthophosphate
SuperoxidesHighly reactive compounds produced when oxygen is reduced by a single electron. In biological systems, they may be generated during the normal catalytic function of a number of enzymes and during the oxidation of hemoglobin to METHEMOGLOBIN. In living organisms, SUPEROXIDE DISMUTASE protects the cell from the deleterious effects of superoxides.
CholesterolThe principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.
glucose, (beta-d)-isomer
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
Hydrogen PeroxideA strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials.
potassiumAn element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE.
nitrosonium iona nitric oxide congener
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
SodiumA member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23.
nitritesSalts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)
hydroxide ion
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
2'-deoxyguanosine 5'-phosphateRN given refers to parent cpd.
Guanosine MonophosphateA guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
bis(3',5')-cyclic diguanylic acid
gamma-D-glutamyl-meso-diaminopimelic acid
Guanosine DiphosphateA guanine nucleotide containing two phosphate groups esterified to the sugar moiety.
cyclic guanosine monophosphate-adenosine monophosphate
s-nitrosoglutathioneA sulfur-containing alkyl thionitrite that is one of the NITRIC OXIDE DONORS.
nitryl chloride
hypothiocyanite ionstructure
adenosine monophosphateAdenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
Thymidine Monophosphate5-Thymidylic acid. A thymine nucleotide containing one phosphate group esterified to the deoxyribose moiety.
acetylglucosamineThe N-acetyl derivative of glucosamine.
hypochlorous acidAn oxyacid of chlorine (HClO) containing monovalent chlorine that acts as an oxidizing or reducing agent.
2,5-dihydroxybenzoic acidRN given refers to parent cpd; a oxidative product of saligenin
perhydroxyl radical
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
n-acetylmuramic acidRN given refers to D-Glucopyranose, (R)-isomer
nitrogen trioxide
Deoxycytidine MonophosphateDeoxycytidine (dihydrogen phosphate). A deoxycytosine nucleotide containing one phosphate group esterified to the deoxyribose moiety in the 2'-,3'- or 5- positions.
Peroxynitrite
hydroxyl radicalThe univalent radical OH. Hydroxyl radical is a potent oxidizing agent.
2'-deoxyadenosine triphosphateRN given refers to unlabeled parent cpd
Coenzyme A
Acetyl Coenzyme AAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.
lipid II
hemeThe color-furnishing portion of hemoglobin. It is found free in tissues and as the prosthetic group in many hemeproteins.
HemeThe color-furnishing portion of hemoglobin. It is found free in tissues and as the prosthetic group in many hemeproteins.
nitrosoperoxycarbonatea peroxynitrite and carbon dioxide adduct involved in oxidative DNA damage
7-ketocholesterolinhibits uptake of cholesterol in rabbit aorta
thiocyanateRN given refers to parent cpd