Page last updated: 2024-10-06

IRF3-mediated induction of type I IFN

Proteins (13)

ProteinSynonymsTaxonomy
Three-prime repair exonuclease 1EC 3.1.11.2; 3'-5' exonuclease TREX1; Deoxyribonuclease III; DNase IIIHomo sapiens (human)
Interferon regulatory factor 3IRF-3Homo sapiens (human)
Double-strand break repair protein MRE11EC 3.1.-.-; Double-strand break repair protein MRE11A; Meiotic recombination 11 homolog 1; MRE11 homolog 1; Meiotic recombination 11 homolog A; MRE11 homolog AHomo sapiens (human)
DNA-dependent protein kinase catalytic subunitDNA-PK catalytic subunit; DNA-PKcs; EC 2.7.11.1; DNPK1; p460Homo sapiens (human)
Serine/threonine-protein kinase TBK1EC 2.7.11.1; NF-kappa-B-activating kinase; T2K; TANK-binding kinase 1Homo sapiens (human)
Stimulator of interferon genes proteinhSTING; Endoplasmic reticulum interferon stimulator; ERIS; Mediator of IRF3 activation; hMITA; Transmembrane protein 173Homo sapiens (human)
X-ray repair cross-complementing protein 6EC 3.6.4.-; EC 4.2.99.-; 5'-deoxyribose-5-phosphate lyase Ku70; 5'-dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; CTC box-binding factor 75 kDa subunit; CTC75; CTCBF; DNAHomo sapiens (human)
X-ray repair cross-complementing protein 5EC 3.6.4.-; 86 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 2; ATP-dependent DNA helicase II 80 kDa subunit; CTC box-binding factor 85 kDa subunit; CTC85; CTCBF; DNA repair protein XRCC5; Ku80; Ku86; Lupus Ku autoantigen protein p86; NuHomo sapiens (human)
NACHT, LRR and PYD domains-containing protein 4Cancer/testis antigen 58; CT58; PAAD and NACHT-containing protein 2; PAN2; PYRIN and NACHT-containing protein 2; PYRIN-containing APAF1-like protein 4; PYPAF4; Ribonuclease inhibitor 2Homo sapiens (human)
Gamma-interferon-inducible protein 16Ifi-16; Interferon-inducible myeloid differentiation transcriptional activatorHomo sapiens (human)
NLR family CARD domain-containing protein 3CARD15-like protein; Caterpiller protein 16.2; CLR16.2; NACHT, LRR and CARD domains-containing protein 3; Nucleotide-binding oligomerization domain protein 3Homo sapiens (human)
Probable ATP-dependent RNA helicase DDX41EC 3.6.4.13; DEAD box protein 41; DEAD box protein abstrakt homologHomo sapiens (human)
E3 ubiquitin-protein ligase DTX4EC 2.3.2.27; Protein deltex-4; Deltex4; RING finger protein 155; RING-type E3 ubiquitin transferase DTX4Homo sapiens (human)

Compounds (4)

CompoundDescription
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
bis(3',5')-cyclic diguanylic acid
cyclic guanosine monophosphate-adenosine monophosphate
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.