Page last updated: 2024-10-06

IL4-mediated signaling events

Proteins (64)

ProteinSynonymsTaxonomy
Interleukin-10IL-10; Cytokine synthesis inhibitory factor; CSIFHomo sapiens (human)
Insulin receptor substrate 1IRS-1Homo sapiens (human)
Tyrosine-protein kinase JAK2EC 2.7.10.2; Janus kinase 2; JAK-2Homo sapiens (human)
Integrin beta-3Platelet membrane glycoprotein IIIa; GPIIIaHomo sapiens (human)
RAC-alpha serine/threonine-protein kinaseEC 2.7.11.1; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alphaHomo sapiens (human)
Mu-type opioid receptorM-OR-1; MOR-1; Mu opiate receptor; Mu opioid receptor; MOP; hMOPHomo sapiens (human)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformPI3-kinase subunit alpha; PI3K-alpha; PI3Kalpha; PtdIns-3-kinase subunit alpha; EC 2.7.1.137; EC 2.7.1.153; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha; PtdIns-3-kinase subunit p110-alpha; p110alpha; Phosphoinositide 3-kHomo sapiens (human)
Tyrosine-protein kinase JAK3EC 2.7.10.2; Janus kinase 3; JAK-3; Leukocyte janus kinase; L-JAKHomo sapiens (human)
Bcl-2-like protein 1Bcl2-L-1; Apoptosis regulator Bcl-XHomo sapiens (human)
Mitogen-activated protein kinase 14MAP kinase 14; MAPK 14; EC 2.7.11.24; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MAP kinase MXI2; MAX-interacting protein 2; Mitogen-activated protein kinase p38 alpha; MAP kinase p38 alpha; Stress-activated Homo sapiens (human)
Polyunsaturated fatty acid lipoxygenase ALOX1512/15-lipoxygenase; Arachidonate 12-lipoxygenase, leukocyte-type; 12-LOX; 1.13.11.31; Arachidonate 15-lipoxygenase; 15-LOX; 15-LOX-1; 1.13.11.33; Arachidonate omega-6 lipoxygenase; Hepoxilin A3 synthase Alox15; 1.13.11.-; Linoleate 13S-lipoxygenase; 1.13.Homo sapiens (human)
Ribosomal protein S6 kinase beta-1S6K-beta-1; S6K1; EC 2.7.11.1; 70 kDa ribosomal protein S6 kinase 1; P70S6K1; p70-S6K 1; Ribosomal protein S6 kinase I; Serine/threonine-protein kinase 14A; p70 ribosomal S6 kinase alpha; p70 S6 kinase alpha; p70 S6K-alpha; p70 S6KAHomo sapiens (human)
Tyrosine-protein kinase JAK1EC 2.7.10.2; Janus kinase 1; JAK-1Homo sapiens (human)
Phosphatidylinositol 3-kinase regulatory subunit alphaPI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alphaHomo sapiens (human)
SHC-transforming protein 1SHC-transforming protein 3; SHC-transforming protein A; Src homology 2 domain-containing-transforming protein C1; SH2 domain protein C1Homo sapiens (human)
Signal transducer and activator of transcription 5AHomo sapiens (human)
Serine/threonine-protein kinase mTOREC 2.7.11.1; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin; mTOR; Mechanistic target of rapamycin; Rapamycin and FKBP12 target 1; Rapamycin target protein 1Homo sapiens (human)
Growth factor receptor-bound protein 2Adapter protein GRB2; Protein Ash; SH2/SH3 adapter GRB2Homo sapiens (human)
B-cell lymphoma 6 proteinBCL-6; B-cell lymphoma 5 protein; BCL-5; Protein LAZ-3; Zinc finger and BTB domain-containing protein 27; Zinc finger protein 51Homo sapiens (human)
CD40 ligandCD40-L; T-cell antigen Gp39; TNF-related activation protein; TRAP; Tumor necrosis factor ligand superfamily member 5Homo sapiens (human)
Single-stranded DNA cytosine deaminaseEC 3.5.4.38; Activation-induced cytidine deaminase; AID; Cytidine aminohydrolaseHomo sapiens (human)
Lymphotoxin-alphaLT-alpha; TNF-beta; Tumor necrosis factor ligand superfamily member 1Homo sapiens (human)
Collagen alpha-2(I) chainAlpha-2 type I collagenHomo sapiens (human)
HLA class II histocompatibility antigen gamma chainHLA-DR antigens-associated invariant chain; Ia antigen-associated invariant chain; IiHomo sapiens (human)
Interleukin-5IL-5; B-cell differentiation factor I; Eosinophil differentiation factor; T-cell replacing factor; TRFHomo sapiens (human)
Arginase-1EC 3.5.3.1; Liver-type arginase; Type I arginaseHomo sapiens (human)
Tyrosine-protein kinase Fes/FpsEC 2.7.10.2; Feline sarcoma/Fujinami avian sarcoma oncogene homolog; Proto-oncogene c-Fes; Proto-oncogene c-Fps; p93c-fesHomo sapiens (human)
P-selectinCD62 antigen-like family member P; Granule membrane protein 140; GMP-140; Leukocyte-endothelial cell adhesion molecule 3; LECAM3; Platelet activation dependent granule-external membrane protein; PADGEMHomo sapiens (human)
Tyrosine-protein phosphatase non-receptor type 6EC 3.1.3.48; Hematopoietic cell protein-tyrosine phosphatase; Protein-tyrosine phosphatase 1C; PTP-1C; Protein-tyrosine phosphatase SHP-1; SH-PTP1Homo sapiens (human)
Signal transducer and activator of transcription 6IL-4 StatHomo sapiens (human)
Signal transducer and activator of transcription 5BHomo sapiens (human)
Protein mono-ADP-ribosyltransferase PARP14EC 2.4.2.-; ADP-ribosyltransferase diphtheria toxin-like 8; ARTD8; B aggressive lymphoma protein 2; Poly [ADP-ribose] polymerase 14; PARP-14Homo sapiens (human)
Transcription factor Sp1Homo sapiens (human)
EotaxinC-C motif chemokine 11; Eosinophil chemotactic protein; Small-inducible cytokine A11Homo sapiens (human)
Low affinity immunoglobulin epsilon Fc receptorBLAST-2; C-type lectin domain family 4 member J; Fc-epsilon-RII; Immunoglobulin E-binding factor; Lymphocyte IgE receptorHomo sapiens (human)
CCAAT/enhancer-binding protein betaC/EBP beta; Liver activator protein; LAP; Liver-enriched inhibitory protein; LIP; Nuclear factor NF-IL6; Transcription factor 5; TCF-5Homo sapiens (human)
Polymeric immunoglobulin receptorPIgR; Poly-Ig receptor; Hepatocellular carcinoma-associated protein TB6Homo sapiens (human)
C-C motif chemokine 17CC chemokine TARC; Small-inducible cytokine A17; Thymus and activation-regulated chemokineHomo sapiens (human)
Trefoil factor 3Intestinal trefoil factor; hITF; Polypeptide P1.B; hP1.BHomo sapiens (human)
Interleukin-4IL-4; B-cell stimulatory factor 1; BSF-1; Binetrakin; Lymphocyte stimulatory factor 1; PitrakinraHomo sapiens (human)
Suppressor of cytokine signaling 1SOCS-1; JAK-binding protein; JAB; STAT-induced STAT inhibitor 1; SSI-1; Tec-interacting protein 3; TIP-3Homo sapiens (human)
Suppressor of cytokine signaling 5SOCS-5; Cytokine-inducible SH2 protein 6; CIS-6; Cytokine-inducible SH2-containing protein 5Homo sapiens (human)
E3 SUMO-protein ligase EGR2EC 2.3.2.-; AT591; E3 SUMO-protein transferase ERG2; Early growth response protein 2; EGR-2; Zinc finger protein Krox-20Homo sapiens (human)
Immunoglobulin heavy constant gamma 3HDC; Heavy chain disease protein; Ig gamma-3 chain C regionHomo sapiens (human)
Cytokine receptor common subunit gammaInterleukin-2 receptor subunit gamma; IL-2 receptor subunit gamma; IL-2R subunit gamma; IL-2RG; gammaC; p64Homo sapiens (human)
Interleukin-4 receptor subunit alphaIL-4 receptor subunit alpha; IL-4R subunit alpha; IL-4R-alpha; IL-4RAHomo sapiens (human)
Suppressor of cytokine signaling 3SOCS-3; Cytokine-inducible SH2 protein 3; CIS-3; STAT-induced STAT inhibitor 3; SSI-3Homo sapiens (human)
Resistin-like betaColon and small intestine-specific cysteine-rich protein; Colon carcinoma-related gene protein; Cysteine-rich secreted protein A12-alpha-like 1; Cysteine-rich secreted protein FIZZ2; RELMbetaHomo sapiens (human)
Interleukin-13 receptor subunit alpha-1IL-13 receptor subunit alpha-1; IL-13R subunit alpha-1; IL-13R-alpha-1; IL-13RA1; Cancer/testis antigen 19; CT19Homo sapiens (human)
E3 ubiquitin-protein ligase CBLEC 2.3.2.27; Casitas B-lineage lymphoma proto-oncogene; Proto-oncogene c-Cbl; RING finger protein 55; RING-type E3 ubiquitin transferase CBL; Signal transduction protein CBLHomo sapiens (human)
Docking protein 2Downstream of tyrosine kinase 2; p56(dok-2)Homo sapiens (human)
Immunoglobulin heavy constant epsilonIg epsilon chain C region; Ig epsilon chain C region NDHomo sapiens (human)
Immunoglobulin heavy constant gamma 1Ig gamma-1 chain C region; Ig gamma-1 chain C region EU; Ig gamma-1 chain C region KOL; Ig gamma-1 chain C region NIEHomo sapiens (human)
Collagen alpha-1(I) chainAlpha-1 type I collagenHomo sapiens (human)
Thy-1 membrane glycoproteinCDw90; Thy-1 antigenHomo sapiens (human)
Protein C-ets-1p54Homo sapiens (human)
High mobility group protein HMG-I/HMG-YHMG-I(Y); High mobility group AT-hook protein 1; High mobility group protein A1; High mobility group protein RHomo sapiens (human)
Transcription factor PU.131 kDa-transforming proteinHomo sapiens (human)
Interleukin-13 receptor subunit alpha-2IL-13 receptor subunit alpha-2; IL-13R subunit alpha-2; IL-13R-alpha-2; IL-13RA2; Interleukin-13-binding proteinHomo sapiens (human)
Interferon regulatory factor 4IRF-4; Lymphocyte-specific interferon regulatory factor; LSIRF; Multiple myeloma oncogene 1; NF-EM5Homo sapiens (human)
Transcription factor IIIATFIIIAHomo sapiens (human)
C-C motif chemokine 26CC chemokine IMAC; Eotaxin-3; Macrophage inflammatory protein 4-alpha; MIP-4-alpha; Small-inducible cytokine A26; Thymic stroma chemokine-1; TSC-1Homo sapiens (human)
Insulin receptor substrate 2IRS-2Homo sapiens (human)
SH2 containing inositol-5-phosphataseHomo sapiens (human)

Compounds (0)

CompoundDescription