Page last updated: 2024-10-06

IL-1_signaling(through_IKK-NFkB_cascade)(canonical) ( IL-1 signaling pathway (through NF-kappaB) )

Proteins (23)

ProteinSynonymsTaxonomy
Myeloid differentiation primary response protein MyD88Mus musculus (house mouse)
Inhibitor of nuclear factor kappa-B kinase subunit alphaI-kappa-B kinase alpha; IKK-A; IKK-alpha; IkBKA; IkappaB kinase; EC 2.7.11.10; Conserved helix-loop-helix ubiquitous kinase; I-kappa-B kinase 1; IKK1; Nuclear factor NF-kappa-B inhibitor kinase alpha; NFKBIKA; Transcription factor 16; TCF-16Homo sapiens (human)
Transcription factor p65 Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3Mus musculus (house mouse)
Interleukin-1 receptor-associated kinase 4IRAK-4; EC 2.7.11.1Mus musculus (house mouse)
Inhibitor of nuclear factor kappa-B kinase subunit betaI-kappa-B-kinase beta; IKK-B; IKK-beta; IkBKB; EC 2.7.11.10; I-kappa-B kinase 2; IKK2; Nuclear factor NF-kappa-B inhibitor kinase beta; NFKBIKB; Serine/threonine protein kinase IKBKB; 2.7.11.1Rattus norvegicus (Norway rat)
Interleukin-1 receptor type 1IL-1R-1; IL-1RT-1; IL-1RT1; EC 3.2.2.6; CD121 antigen-like family member A; Interleukin-1 receptor alpha; IL-1R-alpha; Interleukin-1 receptor type I; p80Mus musculus (house mouse)
Ubiquitin-conjugating enzyme E2 variant 1UEV-1; CROC-1; TRAF6-regulated IKK activator 1 beta Uev1AHomo sapiens (human)
Mitogen-activated protein kinase kinase kinase mom-4EC 2.7.11.25Caenorhabditis elegans
S-phase kinase-associated protein 1Cyclin-A/CDK2-associated protein p19; S-phase kinase-associated protein 1A; p19A; p19skp1Mus musculus (house mouse)
Nuclear factor NF-kappa-B p105 subunit DNA-binding factor KBF1; EBP-1; NF-kappa-B1 p84/NF-kappa-B1 p98; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1Mus musculus (house mouse)
Interleukin-1 receptor accessory proteinIL-1 receptor accessory protein; IL-1RAcP; EC 3.2.2.6Rattus norvegicus (Norway rat)
E3 ubiquitin-protein ligase RBX1EC 2.3.2.27; EC 2.3.2.32; E3 ubiquitin-protein transferase RBX1; RING finger protein 75; RING-box protein 1; Rbx1Mus musculus (house mouse)
Ubiquitin-conjugating enzyme E2 NEC 2.3.2.23; Bendless-like ubiquitin-conjugating enzyme; E2 ubiquitin-conjugating enzyme N; Ubiquitin carrier protein N; Ubiquitin-protein ligase NRattus norvegicus (Norway rat)
Toll-interacting proteinMus musculus (house mouse)
Interleukin-1 alpha IL-1 alphaRattus norvegicus (Norway rat)
TNF receptor-associated factor 6 EC 2.3.2.27; E3 ubiquitin-protein ligase TRAF6; RING-type E3 ubiquitin transferase TRAF6Mus musculus (house mouse)
Cullin homolog 1Lin-19 homolog proteinDrosophila melanogaster (fruit fly)
F-box/WD repeat-containing protein 1ABeta-TrCP protein E3RS-IkappaB; Beta-transducin repeat-containing protein; Beta-TrCP; E3RSIkappaB; mE3RS-IkappaB; F-box and WD repeats protein beta-TrCP; HOS; Ubiquitin ligase FWD1; pIkappaB-E3 receptor subunitMus musculus (house mouse)
Interleukin-1 receptor-associated kinase 1 IRAK; IRAK-1; EC 2.7.11.1; Pelle-like protein kinase; mPLKMus musculus (house mouse)
NF-kappa-B inhibitor alpha I-kappa-B-alpha; IkB-alpha; IkappaBalpha; RL/IF-1Rattus norvegicus (Norway rat)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 Mitogen-activated protein kinase kinase kinase 7-interacting protein 1; TGF-beta-activated kinase 1-binding protein 1; TAK1-binding protein 1Mus musculus (house mouse)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 Mitogen-activated protein kinase kinase kinase 7-interacting protein 2; TAK1-binding protein 2; TAB-2; TGF-beta-activated kinase 1-binding protein 2Mus musculus (house mouse)
NF-kappa-B essential modulatorInhibitor of nuclear factor kappa B kinase subunit gamma; DmIKKgamma; NEMO homologDrosophila melanogaster (fruit fly)

Compounds (0)

CompoundDescription