| Protein | Synonyms | Taxonomy |
|---|
| 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase | EC 4.1.1.45; Picolinate carboxylase | Homo sapiens (human) |
| Glutaryl-CoA dehydrogenase, mitochondrial | GCD; EC 1.3.8.6 | Homo sapiens (human) |
| Hydroxyproline dehydrogenase | HYPDH; EC 1.5.5.3; Kidney and liver proline oxidase 1; HsPOX1; Probable proline dehydrogenase 2; 1.5.5.2; Probable proline oxidase 2 | Homo sapiens (human) |
| Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | P5C dehydrogenase; EC 1.2.1.88; Aldehyde dehydrogenase family 4 member A1; L-glutamate gamma-semialdehyde dehydrogenase | Homo sapiens (human) |
| Maleylacetoacetate isomerase | MAAI; EC 5.2.1.2; GSTZ1-1; Glutathione S-transferase zeta 1; 2.5.1.18 | Homo sapiens (human) |
| Indoleamine 2,3-dioxygenase 1 | IDO-1; EC 1.13.11.52; Indoleamine-pyrrole 2,3-dioxygenase | Homo sapiens (human) |
| Indoleamine 2,3-dioxygenase 2 | IDO-2; EC 1.13.11.-; Indoleamine 2,3-dioxygenase-like protein 1; Indoleamine-pyrrole 2,3-dioxygenase-like protein 1 | Homo sapiens (human) |
| Tyrosine aminotransferase | TAT; EC 2.6.1.5; L-tyrosine:2-oxoglutarate aminotransferase | Homo sapiens (human) |
| Large neutral amino acids transporter small subunit 1 | 4F2 light chain; 4F2 LC; 4F2LC; CD98 light chain; Integral membrane protein E16; E16; L-type amino acid transporter 1; hLAT1; Solute carrier family 7 member 5; y+ system cationic amino acid transporter | Homo sapiens (human) |
| Kynureninase | EC 3.7.1.3; L-kynurenine hydrolase | Homo sapiens (human) |
| Kynurenine--oxoglutarate transaminase 3 | EC 2.6.1.7; Cysteine-S-conjugate beta-lyase 2; 4.4.1.13; Kynurenine aminotransferase 3; Kynurenine aminotransferase III; KATIII; Kynurenine--glyoxylate transaminase; 2.6.1.63; Kynurenine--oxoglutarate transaminase III | Homo sapiens (human) |
| Formimidoyltransferase-cyclodeaminase | Formiminotransferase-cyclodeaminase; FTCD; LCHC1 | Homo sapiens (human) |
| Histamine N-methyltransferase | HMT; EC 2.1.1.8 | Homo sapiens (human) |
| Histidine decarboxylase | HDC; EC 4.1.1.22 | Homo sapiens (human) |
| Mitochondrial 2-oxodicarboxylate carrier | Solute carrier family 25 member 21 | Homo sapiens (human) |
| Tryptophan 2,3-dioxygenase | TDO; EC 1.13.11.11; Tryptamin 2,3-dioxygenase; Tryptophan oxygenase; TO; TRPO; Tryptophan pyrrolase; Tryptophanase | Homo sapiens (human) |
| Kynurenine--oxoglutarate transaminase 1 | EC 2.6.1.7; Cysteine-S-conjugate beta-lyase; 4.4.1.13; Glutamine transaminase K; GTK; Glutamine--phenylpyruvate transaminase; 2.6.1.64; Kynurenine aminotransferase 1; Kynurenine aminotransferase I; KATI; Kynurenine--oxoglutarate transaminase I | Homo sapiens (human) |
| Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | KAT/AadAT; 2-aminoadipate aminotransferase; 2-aminoadipate transaminase; 2.6.1.39; Alpha-aminoadipate aminotransferase; AadAT; Kynurenine aminotransferase II; Kynurenine--oxoglutarate aminotransferase II; Kynurenine--oxoglutarate transaminase 2; 2.6.1.7; | Homo sapiens (human) |
| Phenylalanine-4-hydroxylase | PAH; EC 1.14.16.1; Phe-4-monooxygenase | Homo sapiens (human) |
| Dihydropteridine reductase | EC 1.5.1.34; HDHPR; Quinoid dihydropteridine reductase; Short chain dehydrogenase/reductase family 33C member 1 | Homo sapiens (human) |
| Histidine ammonia-lyase | Histidase; EC 4.3.1.3 | Homo sapiens (human) |
| Peroxisomal sarcosine oxidase | PSO; EC 1.5.3.1; EC 1.5.3.7; L-pipecolate oxidase; L-pipecolic acid oxidase | Homo sapiens (human) |
| Kynurenine formamidase | KFA; KFase; EC 3.5.1.9; Arylformamidase; N-formylkynurenine formamidase; FKF | Homo sapiens (human) |
| Carnosine synthase 1 | EC 6.3.2.11; ATP-grasp domain-containing protein 1 | Homo sapiens (human) |
| Kynurenine 3-monooxygenase | EC 1.14.13.9; Kynurenine 3-hydroxylase | Homo sapiens (human) |
| 4-hydroxyphenylpyruvate dioxygenase | EC 1.13.11.27; 4-hydroxyphenylpyruvic acid oxidase; 4HPPD; HPD; HPPDase | Homo sapiens (human) |
| 3-hydroxyanthranilate 3,4-dioxygenase | EC 1.13.11.6; 3-hydroxyanthranilate oxygenase; 3-HAO; h3HAO; 3-hydroxyanthranilic acid dioxygenase; HAD | Homo sapiens (human) |
| L-amino-acid oxidase | LAAO; LAO; EC 1.4.3.2; EC 1.4.3.25; Interleukin-4-induced protein 1; IL4-induced protein 1; hIL4I1; Protein Fig-1; hFIG1 | Homo sapiens (human) |
| Homogentisate 1,2-dioxygenase | EC 1.13.11.5; Homogentisate oxygenase; Homogentisic acid oxidase; Homogentisicase | Homo sapiens (human) |
| Fumarylacetoacetase | FAA; EC 3.7.1.2; Beta-diketonase; Fumarylacetoacetate hydrolase | Homo sapiens (human) |
| Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial | EC 2.3.1.61; 2-oxoglutarate dehydrogenase complex component E2; OGDC-E2; Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2K | Homo sapiens (human) |
| Isoaspartyl peptidase/L-asparaginase | EC 3.4.19.5; EC 3.5.1.1; Asparaginase-like protein 1; Beta-aspartyl-peptidase; Isoaspartyl dipeptidase; L-asparagine amidohydrolase | Homo sapiens (human) |
| Urocanate hydratase | Urocanase; EC 4.2.1.49; Imidazolonepropionate hydrolase | Homo sapiens (human) |
| Probable imidazolonepropionase | EC 3.5.2.7; Amidohydrolase domain-containing protein 1 | Homo sapiens (human) |
| Pterin-4-alpha-carbinolamine dehydratase | PHS; EC 4.2.1.96; 4-alpha-hydroxy-tetrahydropterin dehydratase; Dimerization cofactor of hepatocyte nuclear factor 1-alpha; DCoH; Dimerization cofactor of HNF1; Phenylalanine hydroxylase-stimulating protein; Pterin carbinolamine dehydratase; PCD | Homo sapiens (human) |
| Hydroxylysine kinase | 5-hydroxy-L-lysine kinase; EC 2.7.1.81; Aminoglycoside phosphotransferase domain-containing protein 1 | Homo sapiens (human) |
| Proline dehydrogenase 1, mitochondrial | EC 1.5.5.2; Proline oxidase; Proline oxidase 2; p53-induced gene 6 protein | Homo sapiens (human) |
| 4F2 cell-surface antigen heavy chain | 4F2hc; 4F2 heavy chain antigen; Lymphocyte activation antigen 4F2 large subunit; Solute carrier family 3 member 2 | Homo sapiens (human) |
| Alpha-aminoadipic semialdehyde dehydrogenase | Alpha-AASA dehydrogenase; EC 1.2.1.31; Aldehyde dehydrogenase family 7 member A1; 1.2.1.3; Antiquitin-1; Betaine aldehyde dehydrogenase; 1.2.1.8; Delta1-piperideine-6-carboxylate dehydrogenase; P6c dehydrogenase | Homo sapiens (human) |
| Ketimine reductase mu-crystallin | EC 1.5.1.25; NADP-regulated thyroid-hormone-binding protein | Homo sapiens (human) |
| Proton-coupled amino acid transporter 4 | Proton/amino acid transporter 4; Solute carrier family 36 member 4 | Homo sapiens (human) |
| 5-phosphohydroxy-L-lysine phospho-lyase | EC 4.2.3.134; Alanine--glyoxylate aminotransferase 2-like 2 | Homo sapiens (human) |
| Carnosine N-methyltransferase | EC 2.1.1.22 | Homo sapiens (human) |
| Alpha-aminoadipic semialdehyde synthase, mitochondrial | LKR/SDH | Homo sapiens (human) |
| Compound | Description |
|---|
| hydronium ion | |
| pyridoxal phosphate | This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE). |
| pyruvic acid | An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed) |
| Orthophosphate | |
| Glutathione | A tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides. |
| ammonium hydroxide | The hydroxy salt of ammonium ion. It is formed when AMMONIA reacts with water molecules in solution. |
| Ammonium | |
| iron | A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN. |
| Carbon Dioxide | A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. |
| NADH | |
| 1,5-dihydro-fad | chromophore component of E coli DNA photolyase |
| Aspartate | |
| Adenosine Triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| fumaric acid | see also record for ferrous fumarate; use FUMARATES for general fumaric acid esters |
| flavin-adenine dinucleotide | A condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972) |
| histamine | An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter. |
| Hydrogen Peroxide | A strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials. |
| methanol | A colorless, flammable liquid used in the manufacture of FORMALDEHYDE and ACETIC ACID, in chemical synthesis, antifreeze, and as a solvent. Ingestion of methanol is toxic and may cause blindness. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| guanosine diphosphate | A guanine nucleotide containing two phosphate groups esterified to the sugar moiety. |
| guanosine triphosphate | Guanosine 5'-(tetrahydrogen triphosphate). A guanine nucleotide containing three phosphate groups esterified to the sugar moiety. |
| 5,6,7,8-tetrahydrofolic acid | RN given refers to (DL)-isomer |
| sapropterin | RN given refers to parent cpd; co-factor required for catalytic activity of nitric oxide synthases |
| 4a-hydroxytetrahydrobiopterin | structure given in first source |
| 2-amino-4-(2-aminoethoxy)butanoic acid, (DL)-isomer | |
| 3-hydroxykynurenine, (L)-isomer | |
| delta-1-pyrroline-5-carboxylate | (L)-isomer is the biologically active form; RN given refers to cpd without isomeric designation; structure |
| imidazol-4-one-5-propionic acid | structure |
| saccharopine | lysine precursor in the aminoadipic acid-lysine pathway in yeast; minor descriptor (75-85); on-line & Index Medicus search LYSINE/analogs & derivatives (75-85); RN given refers to (L)-isomer |
| allysine | structure |
| kynurenine | A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway. |
| alpha-Ketoglutarate | |
| glutamic acid gamma-semialdehyde | straight-chain form of delta(1)-pyrroline-5-carboxylate; RN given refers to cpd with unspecified isomeric designation |
| beta-alanine | An amino acid formed in vivo by the degradation of dihydrouracil and carnosine. Since neuronal uptake and neuronal receptor sensitivity to beta-alanine have been demonstrated, the compound may be a false transmitter replacing GAMMA-AMINOBUTYRIC ACID. A rare genetic disorder, hyper-beta-alaninemia, has been reported. |
| formic acid | RN given refers to parent cpd |
| glutaryl-coenzyme a | |
| tele-methylhistamine | histamine methyltransferase antagonist |
| kynurenic acid | A broad-spectrum excitatory amino acid antagonist used as a research tool. |
| pipecolic acid | RN given refers to cpd without isomeric designation |
| 3-phenylpyruvate | |
| alpha-ketoglutaric acid | |
| glutamate | |
| crotonyl-coenzyme a | |
| NAD | A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed) |
| acetoacetate | |
| alpha-ketoadipic acid | |
| urocanic acid | 4-Imidazoleacrylic acid. |
| indol-3-yl pyruvic acid | |
| 3-hydroxyanthranilic acid | An oxidation product of tryptophan metabolism. It may be a free radical scavenger and a carcinogen. |
| lipoamide | RN given refers to cpd without isomeric designation |
| N'-formylkynurenine | a photochemical breakdown product of tryptophan in proteins; RN given refers to parent cpd without isomeric designation |
| anserine | A dipeptide containing BETA-ALANINE. |
| aspartame | Flavoring agent sweeter than sugar, metabolized as PHENYLALANINE and ASPARTIC ACID. |
| s-adenosylhomocysteine | 5'-S-(3-Amino-3-carboxypropyl)-5'-thioadenosine. Formed from S-adenosylmethionine after transmethylation reactions. |
| carnosine | A naturally occurring dipeptide neuropeptide found in muscles. |
| heme | The color-furnishing portion of hemoglobin. It is found free in tissues and as the prosthetic group in many hemeproteins. |
| creolin | from refined coal tar oils |
| coenzyme a | |
| 4-hydroxyphenylpyruvic acid | RN given refers to parent cpd |