| Protein | Synonyms | Taxonomy |
|---|
| UDP-glucuronosyltransferase 2B11 | UDPGT 2B11; EC 2.4.1.17 | Homo sapiens (human) |
| Porphobilinogen deaminase | PBG-D; EC 2.5.1.61; Hydroxymethylbilane synthase; HMBS; Pre-uroporphyrinogen synthase | Homo sapiens (human) |
| Ferrochelatase, mitochondrial | EC 4.99.1.1; Heme synthase; Protoheme ferro-lyase | Homo sapiens (human) |
| Uroporphyrinogen decarboxylase | UPD; URO-D; EC 4.1.1.37 | Homo sapiens (human) |
| Heme oxygenase 1 | HO-1; EC 1.14.14.18 | Homo sapiens (human) |
| Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial | COX; Coprogen oxidase; Coproporphyrinogenase; EC 1.3.3.3 | Homo sapiens (human) |
| Delta-aminolevulinic acid dehydratase | ALADH; EC 4.2.1.24; Porphobilinogen synthase | Homo sapiens (human) |
| Protoporphyrinogen oxidase | PPO; EC 1.3.3.4 | Homo sapiens (human) |
| Uroporphyrinogen-III synthase | UROIIIS; UROS; EC 4.2.1.75; Hydroxymethylbilane hydrolyase [cyclizing]; Uroporphyrinogen-III cosynthase | Homo sapiens (human) |
| Beta-glucuronidase | EC 3.2.1.31; Beta-G1 | Homo sapiens (human) |
| Ferritin, mitochondrial | EC 1.16.3.1 | Homo sapiens (human) |
| 5-aminolevulinate synthase, nonspecific, mitochondrial | ALAS-H; EC 2.3.1.37; 5-aminolevulinic acid synthase 1; Delta-ALA synthase 1; Delta-aminolevulinate synthase 1 | Homo sapiens (human) |
| Protoheme IX farnesyltransferase, mitochondrial | EC 2.5.1.141; Heme O synthase | Homo sapiens (human) |
| Biliverdin reductase A | BVR A; EC 1.3.1.24; Biliverdin-IX alpha-reductase | Homo sapiens (human) |
| Cytochrome c oxidase assembly protein COX15 homolog | | Homo sapiens (human) |
| Feline leukemia virus subgroup C receptor-related protein 2 | Calcium-chelate transporter; CCT | Homo sapiens (human) |
| Compound | Description |
|---|
| aminolevulinic acid | A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS. |
| ammonium hydroxide | The hydroxy salt of ammonium ion. It is formed when AMMONIA reacts with water molecules in solution. |
| iron | A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN. |
| Carbon Dioxide | A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. |
| carbon monoxide | Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed) |
| Iron | A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN. |
| NADH | |
| uridine diphosphate | A uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety. |
| Hydrogen Peroxide | A strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| uroporphyrin III | |
| Biliverdine | 1,3,6,7-Tetramethyl-4,5-dicarboxyethyl-2,8-divinylbilenone. Biosynthesized from hemoglobin as a precursor of bilirubin. Occurs in the bile of AMPHIBIANS and of birds, but not in normal human bile or serum. |
| porphobilinogen | |
| uroporphyrinogen iii | |
| protoporphyrinogen | |
| uridine diphosphate glucuronic acid | A nucleoside diphosphate sugar which serves as a source of glucuronic acid for polysaccharide biosynthesis. It may also be epimerized to UDP iduronic acid, which donates iduronic acid to polysaccharides. In animals, UDP glucuronic acid is used for formation of many glucosiduronides with various aglycones. |
| coproporphyrinogen iii | |
| farnesyl pyrophosphate | a sesquiterpene that dimerizes to SQUALENE; RN given refers to cpd without isomeric designation |
| bilirubin | A bile pigment that is a degradation product of HEME. |
| NAD | A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed) |
| hydroxymethylbilane | tetrapyrrole intermediate in pigment biosynthesis by Euglena gracilis; universal intermediate in biosynthesis of uroporphyrinogen III; structure given in first source |