Page last updated: 2024-10-06

HS-GAG degradation

Proteins (7)

ProteinSynonymsTaxonomy
Alpha-L-iduronidaseEC 3.2.1.76Homo sapiens (human)
HeparanaseEC 3.2.1.166; Endo-glucoronidase; Heparanase-1; Hpa1Homo sapiens (human)
Inactive heparanase-2Hpa2Homo sapiens (human)
Beta-glucuronidaseEC 3.2.1.31; Beta-G1Homo sapiens (human)
Iduronate 2-sulfataseEC 3.1.6.13; Alpha-L-iduronate sulfate sulfatase; IdursulfaseHomo sapiens (human)
N-sulphoglucosamine sulphohydrolaseEC 3.10.1.1; Sulfoglucosamine sulfamidase; SulphamidaseHomo sapiens (human)
Alpha-N-acetylglucosaminidaseEC 3.2.1.50; N-acetyl-alpha-glucosaminidase; NAGHomo sapiens (human)

Compounds (8)

CompoundDescription
AcetylglucosamineThe N-acetyl derivative of glucosamine.
CalciumA basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
galactoseAn aldohexose that occurs naturally in the D-form in lactose, cerebrosides, gangliosides, and mucoproteins. Deficiency of galactosyl-1-phosphate uridyltransferase (GALACTOSE-1-PHOSPHATE URIDYL-TRANSFERASE DEFICIENCY DISEASE) causes an error in galactose metabolism called GALACTOSEMIA, resulting in elevations of galactose in the blood.
Aspartate
Xylose
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Coenzyme A
Acetyl Coenzyme AAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.