Pathways > Glycosaminoglycan metabolism
Page last updated: 2024-10-06

Glycosaminoglycan metabolism

Proteins (36)

ProteinSynonymsTaxonomy
Arylsulfatase BASB; EC 3.1.6.12; N-acetylgalactosamine-4-sulfatase; G4SHomo sapiens (human)
Alpha-L-iduronidaseEC 3.2.1.76Homo sapiens (human)
Multidrug resistance-associated protein 5ATP-binding cassette sub-family C member 5; Multi-specific organic anion transporter C; MOAT-C; SMRP; pABC11Homo sapiens (human)
Carbohydrate sulfotransferase 14EC 2.8.2.35; Dermatan 4-sulfotransferase 1; D4ST-1; hD4ST1Homo sapiens (human)
Chondroitin sulfate synthase 1EC 2.4.1.175; EC 2.4.1.226; Chondroitin glucuronyltransferase 1; Chondroitin synthase 1; ChSy-1; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferasHomo sapiens (human)
Beta-1,4-galactosyltransferase 1Beta-1,4-GalTase 1; Beta4Gal-T1; b4Gal-T1; EC 2.4.1.-; Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase; Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase; 2.4.1.38; Lactose synthase A protein; 2.4.1.22; N-acetyllactoHomo sapiens (human)
Sodium/hydrogen exchanger 1APNH; Na(+)/H(+) antiporter, amiloride-sensitive; Na(+)/H(+) exchanger 1; NHE-1; Solute carrier family 9 member 1Homo sapiens (human)
HeparanaseEC 3.2.1.166; Endo-glucoronidase; Heparanase-1; Hpa1Homo sapiens (human)
Beta-1,4-galactosyltransferase 3Beta-1,4-GalTase 3; Beta4Gal-T3; b4Gal-T3; EC 2.4.1.-; Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase; Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase; 2.4.1.38; N-acetyllactosamine synthase; 2.4.1.90; Nal synthasHomo sapiens (human)
Beta-1,4-galactosyltransferase 4Beta-1,4-GalTase 4; Beta4Gal-T4; b4Gal-T4; EC 2.4.1.-; Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase; Lactotriaosylceramide beta-1,4-galactosyltransferase; 2.4.1.275; N-acetyllactosamine synthase; 2.4.1.90; Nal synthase; UDP-Gal:betaHomo sapiens (human)
Beta-1,4-galactosyltransferase 2Beta-1,4-GalTase 2; Beta4Gal-T2; b4Gal-T2; EC 2.4.1.-; Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase; Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase; 2.4.1.38; Lactose synthase A protein; 2.4.1.22; N-acetyllactoHomo sapiens (human)
Inactive heparanase-2Hpa2Homo sapiens (human)
Exostosin-2EC 2.4.1.224; EC 2.4.1.225; Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; Multiple exostoses protein 2; Putative tumor suppressor protein EXT2Homo sapiens (human)
Beta-glucuronidaseEC 3.2.1.31; Beta-G1Homo sapiens (human)
N-acetylglucosamine-6-sulfataseEC 3.1.6.14; Glucosamine-6-sulfatase; G6SHomo sapiens (human)
Iduronate 2-sulfataseEC 3.1.6.13; Alpha-L-iduronate sulfate sulfatase; IdursulfaseHomo sapiens (human)
Carbohydrate sulfotransferase 15EC 2.8.2.33; B-cell RAG-associated gene protein; hBRAG; N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase; GalNAc4S-6STHomo sapiens (human)
Beta-1,4-galactosyltransferase 7Beta-1,4-GalTase 7; Beta4Gal-T7; b4Gal-T7; EC 2.4.1.-; Proteoglycan UDP-galactose:beta-xylose beta1,4-galactosyltransferase I; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 7; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 7; UHomo sapiens (human)
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3EC 2.4.1.135; Beta-1,3-glucuronyltransferase 3; Glucuronosyltransferase I; GlcAT-I; UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase; GlcUAT-IHomo sapiens (human)
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2EC 2.4.1.135; Beta-1,3-glucuronyltransferase 2; GlcAT-D; UDP-glucuronosyltransferase S; GlcAT-S; Glucuronosyltransferase SHomo sapiens (human)
Exostosin-1EC 2.4.1.224; EC 2.4.1.225; Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; Multiple exostoses protein 1; Putative tumor suppressor protein EXT1Homo sapiens (human)
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1EC 2.4.1.135; Beta-1,3-glucuronyltransferase 1; Glucuronosyltransferase P; GlcAT-P; UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase; GlcUAT-PHomo sapiens (human)
Heparan sulfate glucosamine 3-O-sulfotransferase 1EC 2.8.2.23; Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1; 3-OST-1; Heparan sulfate 3-O-sulfotransferase 1; h3-OST-1Homo sapiens (human)
Beta-1,3-galactosyltransferase 6Beta-1,3-GalTase 6; Beta3Gal-T6; Beta3GalT6; EC 2.4.1.134; GAG GalTII; Galactosyltransferase II; Galactosylxylosylprotein 3-beta-galactosyltransferase; UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6Homo sapiens (human)
Carbohydrate sulfotransferase 1EC 2.8.2.21; Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 1; GST-1; Keratan sulfate Gal-6 sulfotransferase; KS6ST; KSGal6ST; KSSTHomo sapiens (human)
D-glucuronyl C5-epimeraseEC 5.1.3.17; Heparan sulfate C5-epimerase; Hsepi; Heparin/heparan sulfate:glucuronic acid C5-epimerase; Heparosan-N-sulfate-glucuronate 5-epimeraseHomo sapiens (human)
Beta-1,4-galactosyltransferase 5Beta-1,4-GalTase 5; Beta4Gal-T5; b4Gal-T5; EC 2.4.1.-; Beta-1,4-GalT II; Glucosylceramide beta-1,4-galactosyltransferase; 2.4.1.274; Lactosylceramide synthase; LacCer synthase; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 5; UDP-galactose:beta-N-aceHomo sapiens (human)
N-sulphoglucosamine sulphohydrolaseEC 3.10.1.1; Sulfoglucosamine sulfamidase; SulphamidaseHomo sapiens (human)
Alpha-N-acetylglucosaminidaseEC 3.2.1.50; N-acetyl-alpha-glucosaminidase; NAGHomo sapiens (human)
Hyaluronidase-2Hyal-2; EC 3.2.1.35; Hyaluronoglucosaminidase-2; Lung carcinoma protein 2; LuCa-2Homo sapiens (human)
UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporterHomolog of Fringe connection protein 1; HFRC1; SQV7-like protein; SQV7L; Solute carrier family 35 member D2; UDP-galactose transporter-related protein 8; UGTrel8Homo sapiens (human)
Heparan sulfate 2-O-sulfotransferase 12-O-sulfotransferase; 2OST; EC 2.8.2.-Homo sapiens (human)
Cell migration-inducing and hyaluronan-binding proteinEC 3.2.1.35Homo sapiens (human)
Calcineurin B homologous protein 1Calcineurin B-like protein; Calcium-binding protein CHP; Calcium-binding protein p22; EF-hand calcium-binding domain-containing protein p22Homo sapiens (human)
Beta-1,4-galactosyltransferase 6Beta-1,4-GalTase 6; Beta4Gal-T6; b4Gal-T6; EC 2.4.1.-; Glucosylceramide beta-1,4-galactosyltransferase; 2.4.1.274; Lactosylceramide synthase; LacCer synthase; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 6; UDP-Gal:glucosylceramide beta-1,4-galactosHomo sapiens (human)
Uronyl 2-sulfotransferaseEC 2.8.2.-Homo sapiens (human)

Compounds (20)

CompoundDescription
hydronium ion
AcetylglucosamineThe N-acetyl derivative of glucosamine.
acetic acidProduct of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed)
uridine diphosphateA uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety.
CalciumA basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
ManganeseA trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
galactoseAn aldohexose that occurs naturally in the D-form in lactose, cerebrosides, gangliosides, and mucoproteins. Deficiency of galactosyl-1-phosphate uridyltransferase (GALACTOSE-1-PHOSPHATE URIDYL-TRANSFERASE DEFICIENCY DISEASE) causes an error in galactose metabolism called GALACTOSEMIA, resulting in elevations of galactose in the blood.
Aspartate
Xylose
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
Cytidine MonophosphateCytidine (dihydrogen phosphate). A cytosine nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
Uridine Monophosphate5'-Uridylic acid. A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
adenosine 3'-phosphate-5'-phosphate
Coenzyme A
acetylgalactosamineThe N-acetyl derivative of galactosamine.
Acetyl Coenzyme AAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.
uridine diphosphate n-acetylgalactosamineA nucleoside diphosphate sugar which serves as a source of N-acetylgalactosamine for glycoproteins, sulfatides and cerebrosides.
Adenosine Phosphosulfate5'-Adenylic acid, monoanhydride with sulfuric acid. The initial compound formed by the action of ATP sulfurylase on sulfate ions after sulfate uptake. Synonyms: adenosine sulfatophosphate; APS.
chemdatabank.com