Page last updated: 2024-10-06

Gluconeogenesis from L-Malic Acid

Proteins (20)

ProteinSynonymsTaxonomy
NADP-dependent malic enzymeNADP-ME; EC 1.1.1.40Escherichia coli K-12
Fructose-bisphosphate aldolase class 2FBP aldolase; FBPA; EC 4.1.2.13; Fructose-1,6-bisphosphate aldolase; Fructose-bisphosphate aldolase class IIEscherichia coli K-12
Phosphoenolpyruvate carboxykinase (ATP)PCK; PEP carboxykinase; PEPCK; EC 4.1.1.49Escherichia coli K-12
NAD-dependent malic enzymeNAD-ME; EC 1.1.1.38Escherichia coli K-12
Glucose-6-phosphate isomeraseGPI; EC 5.3.1.9; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHIEscherichia coli K-12
Fructose-bisphosphate aldolase class 1EC 4.1.2.13; Fructose-bisphosphate aldolase class I; FBP aldolaseEscherichia coli K-12
Triosephosphate isomeraseTIM; TPI; EC 5.3.1.1; Triose-phosphate isomeraseEscherichia coli K-12
EnolaseEC 4.2.1.11; 2-phospho-D-glycerate hydro-lyase; 2-phosphoglycerate dehydrataseEscherichia coli K-12
2,3-bisphosphoglycerate-independent phosphoglycerate mutaseBPG-independent PGAM; Phosphoglyceromutase; iPGM; EC 5.4.2.12Escherichia coli K-12
Fructose-1,6-bisphosphatase class 1FBPase class 1; EC 3.1.3.11; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1Escherichia coli K-12
Anaerobic C4-dicarboxylate transporter DcuBEscherichia coli O157:H7
Anaerobic C4-dicarboxylate transporter DcuCEscherichia coli O157:H7
Phosphoglycerate kinaseEC 2.7.2.3Escherichia coli K-12
Aerobic C4-dicarboxylate transport proteinEscherichia coli K-12
Glyceraldehyde-3-phosphate dehydrogenase AGAPDH-A; EC 1.2.1.12; NAD-dependent glyceraldehyde-3-phosphate dehydrogenaseEscherichia coli K-12
Fructose-1,6-bisphosphatase 1 class 2FBPase 1 class 2; EC 3.1.3.11; D-fructose-1,6-bisphosphate 1-phosphohydrolase 1 class 2Escherichia coli K-12
Anaerobic C4-dicarboxylate transporter DcuAEscherichia coli K-12
Fructose-1,6-bisphosphatase 2 class 2FBPase 2 class 2; EC 3.1.3.11; D-fructose-1,6-bisphosphate 1-phosphohydrolase 2 class 2Escherichia coli K-12
Pyridoxal phosphate phosphatase YbhAPLP phosphatase; EC 3.1.3.74Escherichia coli K-12
Phosphoenolpyruvate synthasePEP synthase; EC 2.7.9.2; Pyruvate, water dikinaseEscherichia coli K-12

Compounds (20)

CompoundDescription
hydronium ion
pyruvic acidAn intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
Orthophosphate
succinic acidA water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
NADH
Adenosine TriphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
adenosine monophosphateAdenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
phosphoenolpyruvateA monocarboxylic acid anion derived from selective deprotonation of the carboxy group of phosphoenolpyruvic acid. It is a metabolic intermediate in GLYCOLYSIS; GLUCONEOGENESIS; and other pathways.
NADA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
2-phosphoglycerateRN given refers to cpd without isomeric designation
dihydroxyacetone phosphateAn important intermediate in lipid biosynthesis and in glycolysis.
glycerate 1,3-biphosphate
3-phosphoglycerate
Glyceraldehyde 3-PhosphateAn aldotriose which is an important intermediate in glycolysis and in tryptophan biosynthesis.
oxaloacetic acidA dicarboxylic acid ketone that is an important metabolic intermediate of the CITRIC ACID CYCLE. It can be converted to ASPARTIC ACID by ASPARTATE TRANSAMINASE.
malic acid
creolinfrom refined coal tar oils