Page last updated: 2024-10-06

Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation

Proteins (40)

ProteinSynonymsTaxonomy
Ribosomal oxygenase 260S ribosomal protein L27a histidine hydroxylase; Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA; 1.14.11.-; Histone lysine demethylase MINA; MYC-induced nuclear antigen; Mineral dust-induced gene protein; Nucleolar protein 52; RibHomo sapiens (human)
Ribosomal oxygenase 160S ribosomal protein L8 histidine hydroxylase; Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66; 1.14.11.-; 1.14.11.27; Histone lysine demethylase NO66; Myc-associated protein with JmjC domain; Nucleolar protein 66; hsNO66; RibosomaHomo sapiens (human)
Bifunctional peptidase and arginyl-hydroxylase JMJD5EC 1.14.11.73; EC 3.4.-.-; JmjC domain-containing protein 5; Jumonji C domain-containing protein 5; L-arginine (3R)-hydroxylase KDM8Homo sapiens (human)
Deoxyhypusine hydroxylasehDOHH; EC 1.14.99.29; Deoxyhypusine dioxygenase; Deoxyhypusine monooxygenase; HEAT-like repeat-containing protein 1Homo sapiens (human)
Growth arrest-specific protein 6 GAS-6; AXL receptor tyrosine kinase ligandHomo sapiens (human)
Prolyl 3-hydroxylase OGFOD1EC 1.14.11.-; 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1; Termination and polyadenylation 1 homolog; uS12 prolyl 3-hydroxylaseHomo sapiens (human)
Protein-S-isoprenylcysteine O-methyltransferaseEC 2.1.1.100; Isoprenylcysteine carboxylmethyltransferase; Prenylated protein carboxyl methyltransferase; PPMT; Prenylcysteine carboxyl methyltransferase; pcCMTHomo sapiens (human)
ProthrombinEC 3.4.21.5; Coagulation factor IIHomo sapiens (human)
Coagulation factor IXEC 3.4.21.22; Christmas factor; Plasma thromboplastin component; PTCHomo sapiens (human)
Coagulation factor XEC 3.4.21.6; Stuart factor; Stuart-Prower factorHomo sapiens (human)
Vitamin K-dependent protein CEC 3.4.21.69; Anticoagulant protein C; Autoprothrombin IIA; Blood coagulation factor XIVHomo sapiens (human)
Coagulation factor VIIEC 3.4.21.21; Proconvertin; Serum prothrombin conversion accelerator; SPCAHomo sapiens (human)
FurinEC 3.4.21.75; Dibasic-processing enzyme; Paired basic amino acid residue-cleaving enzyme; PACEHomo sapiens (human)
Elongation factor 2EF-2Homo sapiens (human)
Ketosamine-3-kinaseEC 2.7.1.172; Fructosamine-3-kinase-related protein; FN3K-RP; FN3K-related protein; Protein-psicosamine 3-kinase FN3KRP; 2.7.1.-Homo sapiens (human)
Vitamin K-dependent gamma-carboxylase EC 4.1.1.90; Gamma-glutamyl carboxylase; Peptidyl-glutamate 4-carboxylase; Vitamin K gamma glutamyl carboxylaseHomo sapiens (human)
Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7EC 1.14.11.63; EC 3.4.-.-; JmjC domain-containing protein 7; Jumonji domain-containing protein 7; L-lysine (3S)-hydroxylase JMJD7Homo sapiens (human)
Aspartyl/asparaginyl beta-hydroxylaseEC 1.14.11.16; Aspartate beta-hydroxylase; ASP beta-hydroxylase; Peptide-aspartate beta-dioxygenaseHomo sapiens (human)
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6EC 1.14.11.-; Histone arginine demethylase JMJD6; JmjC domain-containing protein 6; Jumonji domain-containing protein 6; Lysyl-hydroxylase JMJD6; Peptide-lysine 5-dioxygenase JMJD6; Phosphatidylserine receptor; Protein PTDSRHomo sapiens (human)
Coagulation factor VIIIAntihemophilic factor; AHF; Procoagulant componentHomo sapiens (human)
60S ribosomal protein L27aLarge ribosomal subunit protein uL15Homo sapiens (human)
40S ribosomal protein S23Small ribosomal subunit protein uS12Homo sapiens (human)
40S ribosomal protein S6Phosphoprotein NP33; Small ribosomal subunit protein eS6Homo sapiens (human)
60S ribosomal protein L8Large ribosomal subunit protein uL2Homo sapiens (human)
Deoxyhypusine synthaseDHS; EC 2.5.1.46Homo sapiens (human)
OsteocalcinBone Gla protein; BGP; Gamma-carboxyglutamic acid-containing proteinHomo sapiens (human)
Fructosamine-3-kinaseEC 2.7.1.171; Protein-psicosamine 3-kinase FN3K; Protein-ribulosamine 3-kinase FN3K; 2.7.1.172Homo sapiens (human)
Formylglycine-generating enzymeFGE; EC 1.8.3.7; C-alpha-formylglycine-generating enzyme 1; Sulfatase-modifying factor 1Homo sapiens (human)
Vitamin K-dependent protein SHomo sapiens (human)
Diphthine methyltransferaseEC 3.1.1.97; Diphthamide biosynthesis protein 7; WD repeat-containing protein 85Homo sapiens (human)
Vitamin K-dependent protein ZHomo sapiens (human)
Splicing factor U2AF 65 kDa subunitU2 auxiliary factor 65 kDa subunit; hU2AF(65); hU2AF65; U2 snRNP auxiliary factor large subunitHomo sapiens (human)
Eukaryotic peptide chain release factor subunit 1Eukaryotic release factor 1; eRF1; Protein Cl1; TB3-1Homo sapiens (human)
DnaJ homolog subfamily C member 24CSL-type zinc finger-containing protein 3; Diphthamide biosynthesis protein 4Homo sapiens (human)
Diphthine--ammonia ligaseEC 6.3.1.14; ATP-binding domain-containing protein 4; Diphthamide synthase; Diphthamide synthetase; Protein DPH6 homologHomo sapiens (human)
Inactive C-alpha-formylglycine-generating enzyme 2Paralog of formylglycine-generating enzyme; pFGE; Sulfatase-modifying factor 2Homo sapiens (human)
DPH3 homologCSL-type zinc finger-containing protein 2; DelGEF-interacting protein 1; DelGIP1Homo sapiens (human)
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2EC 2.5.1.108; Diphthamide biosynthesis protein 2; Diphtheria toxin resistance protein 2; S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2Homo sapiens (human)
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1EC 2.5.1.108; Diphthamide biosynthesis protein 1; Diphtheria toxin resistance protein 1; Ovarian cancer-associated gene 1 protein; S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1Homo sapiens (human)
Diphthine methyl ester synthaseEC 2.1.1.314; Diphthamide biosynthesis methyltransferaseHomo sapiens (human)

Compounds (22)

CompoundDescription
hydronium ion
Succinate
NADH
Ammonium
ironA metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
ZincA metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
menatetrenone epoxidemetabolite of menatetrenone
adenosine monophosphateAdenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
alpha-Ketoglutarate
trimethylenediamineRN given refers to parent cpd; structure
5'-methylthioadenosinestructure
menatetrenone
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
s-farnesylcysteine alpha-carboxyl methyl esterRN given in first source
SpermidineA polyamine formed from putrescine. It is found in almost all tissues in association with nucleic acids. It is found as a cation at all pH values, and is thought to help stabilize some membranes and nucleic acid structures. It is a precursor of spermine.
adenosine 3'-phosphate-5'-phosphate
s-adenosylmethioninePhysiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)