Pathways > Galactose Degradation/Leloir Pathway
Page last updated: 2024-10-06
Galactose Degradation/Leloir Pathway
Proteins (13)
| Protein | Synonyms | Taxonomy |
|---|
| Beta-galactosidase | Beta-gal; EC 3.2.1.23; Lactase | Escherichia coli K-12 |
| Lactose permease | Lactose-proton symport | Escherichia coli K-12 |
| Galactose-1-phosphate uridylyltransferase | Gal-1-P uridylyltransferase; EC 2.7.7.12; UDP-glucose--hexose-1-phosphate uridylyltransferase | Escherichia coli K-12 |
| Galactokinase | EC 2.7.1.6; Galactose kinase | Escherichia coli K-12 |
| Aldose 1-epimerase | EC 5.1.3.3; Galactose mutarotase; Type-1 mutarotase | Escherichia coli K-12 |
| Phosphocarrier protein HPr | Histidine-containing protein | Escherichia coli K-12 |
| Phosphoglucomutase-1 | PGM 1; EC 5.4.2.2; Glucose phosphomutase 1 | Homo sapiens (human) |
| UDP-glucose 4-epimerase | EC 5.1.3.2; Galactowaldenase; UDP-galactose 4-epimerase | Escherichia coli K-12 |
| Galactose-proton symporter | Galactose transporter | Escherichia coli K-12 |
| UTP--glucose-1-phosphate uridylyltransferase | EC 2.7.7.9; Alpha-D-glucosyl-1-phosphate uridylyltransferase; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase | Escherichia coli K-12 |
| PTS system glucose-specific EIIA component | EIIA-Glc; EIII-Glc; Glucose-specific phosphotransferase enzyme IIA component | Escherichia coli K-12 |
| PTS system glucose-specific EIICB component | EIICB-Glc; EII-Glc | Escherichia coli K-12 |
| Beta-phosphoglucomutase | Beta-PGM; EC 5.4.2.6 | Escherichia coli K-12 |
Compounds (14)
| Compound | Description |
|---|
| hydronium ion | |
| galactose | An aldohexose that occurs naturally in the D-form in lactose, cerebrosides, gangliosides, and mucoproteins. Deficiency of galactosyl-1-phosphate uridyltransferase (GALACTOSE-1-PHOSPHATE URIDYL-TRANSFERASE DEFICIENCY DISEASE) causes an error in galactose metabolism called GALACTOSEMIA, resulting in elevations of galactose in the blood. |
| galactose | An aldohexose that occurs naturally in the D-form in lactose, cerebrosides, gangliosides, and mucoproteins. Deficiency of galactosyl-1-phosphate uridyltransferase (GALACTOSE-1-PHOSPHATE URIDYL-TRANSFERASE DEFICIENCY DISEASE) causes an error in galactose metabolism called GALACTOSEMIA, resulting in elevations of galactose in the blood. |
| Adenosine Triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| uridine triphosphate | Uridine 5'-(tetrahydrogen triphosphate). A uracil nucleotide containing three phosphate groups esterified to the sugar moiety. |
| glucose, (beta-d)-isomer | |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| galactose-1-phosphate | |
| uridine diphosphate galactose | A nucleoside diphosphate sugar which can be epimerized into UDPglucose for entry into the mainstream of carbohydrate metabolism. Serves as a source of galactose in the synthesis of lipopolysaccharides, cerebrosides, and lactose. |
| glucose-1-phosphate | RN given refers to (alpha-D-Glc)-isomer |
| Glucose-6-Phosphate | An ester of glucose with phosphoric acid, made in the course of glucose metabolism by mammalian and other cells. It is a normal constituent of resting muscle and probably is in constant equilibrium with fructose-6-phosphate. (Stedman, 26th ed) |
| pyrophosphate | |
| glucose | A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement. |