| Protein | Synonyms | Taxonomy |
|---|
| 5,6-dihydroxyindole-2-carboxylic acid oxidase | DHICA oxidase; EC 1.14.18.-; Catalase B; Glycoprotein 75; Melanoma antigen gp75; Tyrosinase-related protein 1; TRP; TRP-1; TRP1 | Homo sapiens (human) |
| G-protein coupled receptor 143 | Ocular albinism type 1 protein | Homo sapiens (human) |
| Melanocyte-stimulating hormone receptor | MSH-R; Melanocortin receptor 1; MC1-R | Homo sapiens (human) |
| L-dopachrome tautomerase | DCT; DT; EC 5.3.3.12; L-dopachrome Delta-isomerase; Tyrosinase-related protein 2; TRP-2; TRP2 | Homo sapiens (human) |
| Microphthalmia-associated transcription factor | Class E basic helix-loop-helix protein 32; bHLHe32 | Homo sapiens (human) |
| Melanocyte protein PMEL | ME20-M; ME20M; Melanocyte protein Pmel 17; Melanocytes lineage-specific antigen GP100; Melanoma-associated ME20 antigen; P1; P100; Premelanosome protein; Silver locus protein homolog | Homo sapiens (human) |
| Melanoma antigen recognized by T-cells 1 | MART-1; Antigen LB39-AA; Antigen SK29-AA; Protein Melan-A | Homo sapiens (human) |
| Compound | Description |
|---|
| diphosphoric acid | |
| Calcium | A basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes. |
| levodopa | The naturally occurring form of DIHYDROXYPHENYLALANINE and the immediate precursor of DOPAMINE. Unlike dopamine itself, it can be taken orally and crosses the blood-brain barrier. It is rapidly taken up by dopaminergic neurons and converted to DOPAMINE. It is used for the treatment of PARKINSONIAN DISORDERS and is usually given with agents that inhibit its conversion to dopamine outside of the central nervous system. |
| tyrosine | A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin. |
| Dopamine | One of the catecholamine NEUROTRANSMITTERS in the brain. It is derived from TYROSINE and is the precursor to NOREPINEPHRINE and EPINEPHRINE. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (RECEPTORS, DOPAMINE) mediate its action. |
| 5,6-dihydroxy-2-indolylcarboxylic acid | |
| dopaquinone | proposed metabolite in pathway from tyrosine to dopachrome; RN given refers to cpd without isomeric designation; structure given in first source |
| inositol 1,3,4-trisphosphate | |
| adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| 5,6-dihydroxyindole | |
| Cyclic AMP | An adenine nucleotide containing one phosphate group which is esterified to both the 3'- and 5'-positions of the sugar moiety. It is a second messenger and a key intracellular regulator, functioning as a mediator of activity for a number of hormones, including epinephrine, glucagon, and ACTH. |