Page last updated: 2024-10-06
GABA metabolism (aka GHB)
Proteins (11)
| Protein | Synonyms | Taxonomy |
|---|
| Glutaminase liver isoform, mitochondrial | GLS; EC 3.5.1.2; L-glutaminase; L-glutamine amidohydrolase | Homo sapiens (human) |
| Glutamate decarboxylase 1 | EC 4.1.1.15; 67 kDa glutamic acid decarboxylase; GAD-67; Glutamate decarboxylase 67 kDa isoform | Homo sapiens (human) |
| Amine oxidase [flavin-containing] B | EC 1.4.3.4; Monoamine oxidase type B; MAO-B | Homo sapiens (human) |
| 4-aminobutyrate aminotransferase, mitochondrial | EC 2.6.1.19; (S)-3-amino-2-methylpropionate transaminase; 2.6.1.22; GABA aminotransferase; GABA-AT; Gamma-amino-N-butyrate transaminase; GABA transaminase; GABA-T; L-AIBAT | Homo sapiens (human) |
| Serum paraoxonase/lactonase 3 | EC 3.1.1.2; EC 3.1.1.81; EC 3.1.8.1 | Homo sapiens (human) |
| Dipeptidase 1 | EC 3.4.13.19; Beta-lactamase; 3.5.2.6; Dehydropeptidase-I; Microsomal dipeptidase; Renal dipeptidase; hRDP | Homo sapiens (human) |
| Hydroxyacid-oxoacid transhydrogenase, mitochondrial | HOT; EC 1.1.99.24; Alcohol dehydrogenase iron-containing protein 1; ADHFe1; Fe-containing alcohol dehydrogenase | Homo sapiens (human) |
| Glutamate decarboxylase 2 | EC 4.1.1.15; 65 kDa glutamic acid decarboxylase; GAD-65; Glutamate decarboxylase 65 kDa isoform | Homo sapiens (human) |
| Glutaminase kidney isoform, mitochondrial | GLS; EC 3.5.1.2; K-glutaminase; L-glutamine amidohydrolase | Homo sapiens (human) |
| Succinate-semialdehyde dehydrogenase, mitochondrial | EC 1.2.1.24; Aldehyde dehydrogenase family 5 member A1; NAD(+)-dependent succinic semialdehyde dehydrogenase | Homo sapiens (human) |
| Aflatoxin B1 aldehyde reductase member 2 | EC 1.1.1.n11; AFB1 aldehyde reductase 1; AFB1-AR 1; Aldoketoreductase 7; Succinic semialdehyde reductase; SSA reductase | Homo sapiens (human) |
Compounds (20)
| Compound | Description |
|---|
| 4-hydroxybutyric acid | was an entry term to Sodium Oxybate (74-98) |
| pyridoxal phosphate | This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE). |
| Succinate | |
| 4-hydroxybutyric acid | was an entry term to Sodium Oxybate (74-98) |
| glutamic acid | A non-essential amino acid naturally occurring in the L-form. Glutamic acid is the most common excitatory neurotransmitter in the CENTRAL NERVOUS SYSTEM. |
| Glutamine | A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from GLUTAMIC ACID and AMMONIA. It is the principal carrier of NITROGEN in the body and is an important energy source for many cells. |
| glycolic acid | RN given refers to parent cpd |
| 4-hydroxybutanal | metabolite of 5-fluorouracil; structure in first source |
| homocarnosine | RN given refers to parent cpd |
| uracil | One of four nucleotide bases in the nucleic acid RNA. |
| alpha-Ketoglutarate | |
| beta-alanine | An amino acid formed in vivo by the degradation of dihydrouracil and carnosine. Since neuronal uptake and neuronal receptor sensitivity to beta-alanine have been demonstrated, the compound may be a false transmitter replacing GAMMA-AMINOBUTYRIC ACID. A rare genetic disorder, hyper-beta-alaninemia, has been reported. |
| D-2-hydroxyglutarate | |
| hydracrylic acid | |
| 4-butyrolactone | One of the FURANS with a carbonyl thereby forming a cyclic lactone. It is an endogenous compound made from gamma-aminobutyrate and is the precursor of gamma-hydroxybutyrate. It is also used as a pharmacological agent and solvent. |
| malonic semialdehyde | RN given refers to parent cpd; structure given in first source |
| putrescine | A toxic diamine formed by putrefaction from the decarboxylation of arginine and ornithine. |
| n-acetylputrescine | |
| 3,4-dihydroxybutanoic acid | endogenous sugar acid from serum of fasted rates acting as satiety factor in rats; RN given refers to parent cpd |
| 1,4-butanediol | |