Page last updated: 2024-10-06

Fosphenytoin (Antiarrhythmic) Metabolism Pathway

Proteins (4)

ProteinSynonymsTaxonomy
Sodium channel protein type 5 subunit alphaSodium channel protein cardiac muscle subunit alpha; Sodium channel protein type V subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.5; hH1Homo sapiens (human)
Beta-2-syntrophin59 kDa dystrophin-associated protein A1 basic component 2; Syntrophin-3; SNT3; Syntrophin-like; SNTLHomo sapiens (human)
Alpha-1-syntrophin59 kDa dystrophin-associated protein A1 acidic component 1; Pro-TGF-alpha cytoplasmic domain-interacting protein 1; TACIP1; Syntrophin-1Homo sapiens (human)
Beta-1-syntrophin59 kDa dystrophin-associated protein A1 basic component 1; DAPA1B; BSYN2; Syntrophin-2; Tax interaction protein 43; TIP-43Homo sapiens (human)

Compounds (2)

CompoundDescription
phenytoinAn anticonvulsant that is used to treat a wide variety of seizures. It is also an anti-arrhythmic and a muscle relaxant. The mechanism of therapeutic action is not clear, although several cellular actions have been described including effects on ion channels, active transport, and general membrane stabilization. The mechanism of its muscle relaxant effect appears to involve a reduction in the sensitivity of muscle spindles to stretch. Phenytoin has been proposed for several other therapeutic uses, but its use has been limited by its many adverse effects and interactions with other drugs.
fosphenytoinstructure given in first & second source