Page last updated: 2024-10-06

Fosinopril Action Pathway

Proteins (3)

ProteinSynonymsTaxonomy
ReninEC 3.4.23.15; AngiotensinogenaseHomo sapiens (human)
AngiotensinogenSerpin A8Homo sapiens (human)
Angiotensin-converting enzyme ACE; EC 3.2.1.-; EC 3.4.15.1; Dipeptidyl carboxypeptidase I; Kininase IIHomo sapiens (human)

Compounds (3)

CompoundDescription
angiotensin iiAn octapeptide that is a potent but labile vasoconstrictor. It is produced from angiotensin I after the removal of two amino acids at the C-terminal by ANGIOTENSIN CONVERTING ENZYME. The amino acid in position 5 varies in different species. To block VASOCONSTRICTION and HYPERTENSION effect of angiotensin II, patients are often treated with ACE INHIBITORS or with ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS.
fosinoprilatactive phosphinic acid metabolite of prodrug fosenopril, which is activated by esterases in vivo; structure given in first source; binds zinc with phosphinic acid group
angiotensin i, ile(5)-