Page last updated: 2024-10-06

Formation of Fibrin Clot (Clotting Cascade)

Proteins (37)

ProteinSynonymsTaxonomy
Kininogen-1 Alpha-2-thiol proteinase inhibitor; Fitzgerald factor; High molecular weight kininogen; HMWK; Williams-Fitzgerald-Flaujeac factorHomo sapiens (human)
Plasma serine protease inhibitorAcrosomal serine protease inhibitor; Plasminogen activator inhibitor 3; PAI-3; PAI3; Protein C inhibitor; PCI; Serpin A5Homo sapiens (human)
Plasma kallikreinEC 3.4.21.34; Fletcher factor; Kininogenin; Plasma prekallikrein; PKKHomo sapiens (human)
Lysosomal Pro-X carboxypeptidaseEC 3.4.16.2; Angiotensinase C; Lysosomal carboxypeptidase C; Proline carboxypeptidase; Prolylcarboxypeptidase; PRCPHomo sapiens (human)
ProthrombinEC 3.4.21.5; Coagulation factor IIHomo sapiens (human)
Coagulation factor IXEC 3.4.21.22; Christmas factor; Plasma thromboplastin component; PTCHomo sapiens (human)
Coagulation factor XEC 3.4.21.6; Stuart factor; Stuart-Prower factorHomo sapiens (human)
Coagulation factor XIIEC 3.4.21.38; Hageman factor; HAFHomo sapiens (human)
Antithrombin-IIIATIII; Serpin C1Homo sapiens (human)
Vitamin K-dependent protein CEC 3.4.21.69; Anticoagulant protein C; Autoprothrombin IIA; Blood coagulation factor XIVHomo sapiens (human)
Coagulation factor VIIEC 3.4.21.21; Proconvertin; Serum prothrombin conversion accelerator; SPCAHomo sapiens (human)
MyeloblastinEC 3.4.21.76; AGP7; C-ANCA antigen; Leukocyte proteinase 3; PR-3; PR3; Neutrophil proteinase 4; NP-4; P29; Wegener autoantigenHomo sapiens (human)
Proteinase-activated receptor 1PAR-1; Coagulation factor II receptor; Thrombin receptorHomo sapiens (human)
Tissue factor pathway inhibitorTFPI; Extrinsic pathway inhibitor; EPI; Lipoprotein-associated coagulation inhibitor; LACIHomo sapiens (human)
Coagulation factor VActivated protein C cofactor; Proaccelerin, labile factorHomo sapiens (human)
Coagulation factor XIII B chainFibrin-stabilizing factor B subunit; Protein-glutamine gamma-glutamyltransferase B chain; Transglutaminase B chainHomo sapiens (human)
Coagulation factor VIIIAntihemophilic factor; AHF; Procoagulant componentHomo sapiens (human)
Coagulation factor XIII A chainCoagulation factor XIIIa; EC 2.3.2.13; Protein-glutamine gamma-glutamyltransferase A chain; Transglutaminase A chainHomo sapiens (human)
Coagulation factor XIFXI; EC 3.4.21.27; Plasma thromboplastin antecedent; PTAHomo sapiens (human)
von Willebrand factorvWFHomo sapiens (human)
Tissue factorTF; Coagulation factor III; ThromboplastinHomo sapiens (human)
Alpha-2-macroglobulinAlpha-2-M; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5Homo sapiens (human)
Endothelial protein C receptorActivated protein C receptor; APC receptor; Endothelial cell protein C receptorHomo sapiens (human)
Complement component 1 Q subcomponent-binding protein, mitochondrialASF/SF2-associated protein p32; Glycoprotein gC1qBP; C1qBP; Hyaluronan-binding protein 1; Mitochondrial matrix protein p32; gC1q-R protein; p33; SF2AP32Homo sapiens (human)
Heparin cofactor 2Heparin cofactor II; HC-II; Protease inhibitor leuserpin-2; HLS2; Serpin D1Homo sapiens (human)
ThrombomodulinTM; FetomodulinHomo sapiens (human)
Vitamin K-dependent protein SHomo sapiens (human)
Glia-derived nexinGDN; Peptidase inhibitor 7; PI-7; Protease nexin 1; PN-1; Protease nexin I; Serpin E2Homo sapiens (human)
Plasma protease C1 inhibitorC1 Inh; C1Inh; C1 esterase inhibitor; C1-inhibiting factor; Serpin G1Homo sapiens (human)
Fibrinogen alpha chainHomo sapiens (human)
Fibrinogen beta chainHomo sapiens (human)
Fibrinogen gamma chainHomo sapiens (human)
Platelet glycoprotein Ib alpha chainGP-Ib alpha; GPIb-alpha; GPIbA; Glycoprotein Ibalpha; Antigen CD42b-alphaHomo sapiens (human)
Platelet glycoprotein Ib beta chainGP-Ib beta; GPIb-beta; GPIbB; Antigen CD42b-betaHomo sapiens (human)
Platelet glycoprotein IXGP-IX; GPIX; Glycoprotein 9Homo sapiens (human)
Platelet glycoprotein VGPV; Glycoprotein 5Homo sapiens (human)
CD177 antigenHuman neutrophil alloantigen 2a; HNA-2a; NB1 glycoprotein; NB1 GP; Polycythemia rubra vera protein 1; PRV-1Homo sapiens (human)

Compounds (3)

CompoundDescription
Ammonium
CalciumA basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
ZincA metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.