Page last updated: 2024-10-06
Forasartan Action Pathway
Proteins (4)
Protein | Synonyms | Taxonomy |
Renin | EC 3.4.23.15; Angiotensinogenase | Homo sapiens (human) |
Type-1 angiotensin II receptor | AT1AR; AT1BR; Angiotensin II type-1 receptor; AT1 | Homo sapiens (human) |
Angiotensinogen | Serpin A8 | Homo sapiens (human) |
Angiotensin-converting enzyme | ACE; EC 3.2.1.-; EC 3.4.15.1; Dipeptidyl carboxypeptidase I; Kininase II | Homo sapiens (human) |
Compounds (3)
Compound | Description |
forasartan | structure given in first source; an angiotensin AT(1) receptor antagonist; angiotensin II receptor antagonist; used in treatment of congestive heart failure |
angiotensin ii | An octapeptide that is a potent but labile vasoconstrictor. It is produced from angiotensin I after the removal of two amino acids at the C-terminal by ANGIOTENSIN CONVERTING ENZYME. The amino acid in position 5 varies in different species. To block VASOCONSTRICTION and HYPERTENSION effect of angiotensin II, patients are often treated with ACE INHIBITORS or with ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS. |
angiotensin i, ile(5)- | |