| Protein | Synonyms | Taxonomy |
|---|
| Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial | | Homo sapiens (human) |
| Serine hydroxymethyltransferase, mitochondrial | SHMT; EC 2.1.2.1; Glycine hydroxymethyltransferase; Serine methylase | Homo sapiens (human) |
| Sepiapterin reductase | SPR; EC 1.1.1.153 | Homo sapiens (human) |
| Folylpolyglutamate synthase, mitochondrial | EC 6.3.2.17; Folylpoly-gamma-glutamate synthetase; FPGS; Tetrahydrofolylpolyglutamate synthase; Tetrahydrofolate synthase | Homo sapiens (human) |
| 6-pyruvoyl tetrahydrobiopterin synthase | PTP synthase; PTPS; EC 4.2.3.12 | Homo sapiens (human) |
| Serine hydroxymethyltransferase, cytosolic | SHMT; EC 2.1.2.1; Glycine hydroxymethyltransferase; Serine methylase | Homo sapiens (human) |
| Dihydrofolate reductase | EC 1.5.1.3 | Homo sapiens (human) |
| Thymidylate synthase | TS; TSase; EC 2.1.1.45 | Homo sapiens (human) |
| Bifunctional purine biosynthesis protein ATIC | AICAR transformylase/inosine monophosphate cyclohydrolase; ATIC | Homo sapiens (human) |
| Formimidoyltransferase-cyclodeaminase | Formiminotransferase-cyclodeaminase; FTCD; LCHC1 | Homo sapiens (human) |
| Trifunctional purine biosynthetic protein adenosine-3 | | Homo sapiens (human) |
| Methionine synthase | MS; EC 2.1.1.13; 5-methyltetrahydrofolate--homocysteine methyltransferase; Cobalamin-dependent methionine synthase; Vitamin-B12 dependent methionine synthase | Homo sapiens (human) |
| Dihydropteridine reductase | EC 1.5.1.34; HDHPR; Quinoid dihydropteridine reductase; Short chain dehydrogenase/reductase family 33C member 1 | Homo sapiens (human) |
| C-1-tetrahydrofolate synthase, cytoplasmic | C1-THF synthase | Homo sapiens (human) |
| Monofunctional C1-tetrahydrofolate synthase, mitochondrial | EC 6.3.4.3; Formyltetrahydrofolate synthetase | Homo sapiens (human) |
| Cytosolic 10-formyltetrahydrofolate dehydrogenase | 10-FTHFDH; FDH; EC 1.5.1.6; Aldehyde dehydrogenase family 1 member L1 | Homo sapiens (human) |
| 5-formyltetrahydrofolate cyclo-ligase | EC 6.3.3.2; 5,10-methenyl-tetrahydrofolate synthetase; MTHFS; Methenyl-THF synthetase | Homo sapiens (human) |
| GTP cyclohydrolase 1 | EC 3.5.4.16; GTP cyclohydrolase I; GTP-CH-I | Homo sapiens (human) |
| Methylenetetrahydrofolate reductase | EC 1.5.1.20 | Homo sapiens (human) |
| Aminomethyltransferase, mitochondrial | EC 2.1.2.10; Glycine cleavage system T protein; GCVT | Homo sapiens (human) |
| Compound | Description |
|---|
| phosphoric acid | concise etchant is 37% H3PO4 |
| levoleucovorin | A folate analog consisting of the pharmacologically active isomer of LEUCOVORIN. |
| 5-methyltetrahydrofolate | |
| sapropterin | RN given refers to parent cpd; co-factor required for catalytic activity of nitric oxide synthases |
| folic acid | A member of the vitamin B family that stimulates the hematopoietic system. It is present in the liver and kidney and is found in mushrooms, spinach, yeast, green leaves, and grasses (POACEAE). Folic acid is used in the treatment and prevention of folate deficiencies and megaloblastic anemia. |
| ammonium hydroxide | The hydroxy salt of ammonium ion. It is formed when AMMONIA reacts with water molecules in solution. |
| Carbon Dioxide | A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. |
| glutamic acid | A non-essential amino acid naturally occurring in the L-form. Glutamic acid is the most common excitatory neurotransmitter in the CENTRAL NERVOUS SYSTEM. |
| NADH | |
| Adenosine Triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| methionine | A sulfur-containing essential L-amino acid that is important in many body functions. |
| glycine | A non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| triphosphoric acid | used as water softener, peptizing agent, emulsifier & dispersing agent; ingredient of cleansers; meat preservative; RN given refers to parent cpd; structure |
| dihydrofolate | RN given refers to (L)-isomer |
| dihydroneopterin triphosphate | |
| guanosine triphosphate | Guanosine 5'-(tetrahydrogen triphosphate). A guanine nucleotide containing three phosphate groups esterified to the sugar moiety. |
| 5,6,7,8-tetrahydrofolic acid | RN given refers to (DL)-isomer |
| 4a-carbinolamine tetrahydrobiopterin | structure given in first source |
| dihydropteroate | structure |
| dyspropterin | intermediate in biosynthetic pathway of tetrahydrobiopterin; structure given in first source |
| phosphoribosyl-N-formylglycineamide | |
| glycineamide ribonucleotide | structure |
| formiminoglutamic acid | Measurement of this acid in the urine after oral administration of histidine provides the basis for the diagnostic test of folic acid deficiency and of megaloblastic anemia of pregnancy. |
| NAD | A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed) |
| serine | A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids. |
| thymidine monophosphate | 5-Thymidylic acid. A thymine nucleotide containing one phosphate group esterified to the deoxyribose moiety. |
| 5-formamidoimidazole-4-carboxamide ribotide | purine precursor |
| creolin | from refined coal tar oils |
| 2'-deoxyuridylic acid | RN given refers to parent cpd |
| aica ribonucleotide | purine precursor that has antineoplastic activity |
| homocysteine | A thiol-containing amino acid formed by a demethylation of METHIONINE. |