Page last updated: 2024-10-06

Fluoropyrimidine activity

Proteins (0)

Compounds (13)

CompoundDescription
leucovorinThe active metabolite of FOLIC ACID. Leucovorin is used principally as an antidote to FOLIC ACID ANTAGONISTS.
fluorouracilA pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
capecitabineA deoxycytidine derivative and fluorouracil PRODRUG that is used as an ANTINEOPLASTIC ANTIMETABOLITE in the treatment of COLON CANCER; BREAST CANCER and GASTRIC CANCER.
dihydrofolateRN given refers to (L)-isomer
5-fluorouridine 5'-triphosphate
5-formyl-2'-deoxyuridine 5'-triphosphate
5'-deoxy-5-fluorocytidinestructure in first source
5-fluorodihydrouracilmetabolite of 5-fluorouracil; RN given refers to parent cpd
alpha-fluoro-beta-alaninemetabolite of HCFU & 5-fluorouracil; structure in first source
thymidine monophosphate5-Thymidylic acid. A thymine nucleotide containing one phosphate group esterified to the deoxyribose moiety.
alpha-fluoro-beta-ureidopropionic acidfluorouracil metabolite; structure given in first source
2'-deoxyuridylic acidRN given refers to parent cpd
fluorodeoxyuridylate5-Fluoro-2'-deoxyuridylate. An inhibitor of thymidylate synthetase. Formed from 5-fluorouracil or 5-fluorodeoxyuridine.