Page last updated: 2024-10-06

Flavone and Flavonol Biosynthesis

Proteins (6)

ProteinSynonymsTaxonomy
Flavonoid 3'-monooxygenaseEC 1.14.14.82; Cytochrome P450 75B1; Flavonoid 3'-hydroxylase; AtF3'H; Protein TRANSPARENT TESTA 7Arabidopsis thaliana (thale cress)
Flavone 3'-O-methyltransferase 1AtOMT1; EC 2.1.1.42; Acetylserotonin O-methyltransferase OMT1; 2.1.1.4; Caffeate O-methyltransferase 1; 2.1.1.68; Quercetin 3'-O-methyltransferase 1Arabidopsis thaliana (thale cress)
Flavonol 3-O-glucosyltransferaseEC 2.4.1.91; Anthocyanin 3-O-glucosyltransferase; UDP glucose:flavonoid 3-O-glucosyltransferase; UDP-glycosyltransferase 78D2Arabidopsis thaliana (thale cress)
Flavonol synthase/flavanone 3-hydroxylaseEC 1.14.11.9; EC 1.14.20.6; FLS 1Arabidopsis thaliana (thale cress)
Cytosolic sulfotransferase 5AtSOT5; EC 2.8.2.-; Flavonoid 7-sulfotransferase 3a; AtST3aArabidopsis thaliana (thale cress)
Flavonol-3-O-rhamnosyltransferaseEC 2.4.1.-; UDP-glycosyltransferase 78D1; UDP-rhamnose:flavonol 3-O-glucoside rhamnosyltransferaseArabidopsis thaliana (thale cress)

Compounds (23)

CompoundDescription
hydronium ion
succinic acidA water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
apigenin5,7,4'-trihydroxy-flavone, one of the FLAVONES.
uridine diphosphateA uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
quercetin 3'-sulfate
aromadedrininhibits protein kinase C; the dihydro makes it a flavone rather than a flavonol
adenosine 3'-phosphate-5'-phosphate
alpha-ketoglutaric acid
quercetinA flavonol widely distributed in plants. It is an antioxidant, like many other phenolic heterocyclic compounds. Glycosylated forms include RUTIN and quercetrin.
luteolin5,7,3',4'-tetrahydroxy-flavone, one of the FLAVONES.
quercitrin
quercetin 3-o-glucopyranosidestructure in first source
kaempferol
3-methylquercetin
astragalin
kaempferol 3-o-rhamnosidefrom apple (Malus domestica) leaves; structure in first source
phosphoadenosine phosphosulfate3'-Phosphoadenosine-5'-phosphosulfate. Key intermediate in the formation by living cells of sulfate esters of phenols, alcohols, steroids, sulfated polysaccharides, and simple esters, such as choline sulfate. It is formed from sulfate ion and ATP in a two-step process. This compound also is an important step in the process of sulfur fixation in plants and microorganisms.
UDP-rhamnose
s-adenosylmethioninePhysiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)
taxifolina key intermediate between FLAVONOLS and FLAVANOLIGNINS