Page last updated: 2024-10-06

Felbamate Metabolism Pathway

Proteins (4)

ProteinSynonymsTaxonomy
Cytochrome P450 3A4EC 1.14.14.1; 1,4-cineole 2-exo-monooxygenase; 1,8-cineole 2-exo-monooxygenase; 1.14.14.56; Albendazole monooxygenase (sulfoxide-forming); 1.14.14.73; Albendazole sulfoxidase; CYPIIIA3; CYPIIIA4; Cholesterol 25-hydroxylase; Cytochrome P450 3A3; CytochromeHomo sapiens (human)
Cytochrome P450 2E1EC 1.14.14.1; 4-nitrophenol 2-hydroxylase; 1.14.13.n7; CYPIIE1; Cytochrome P450-JHomo sapiens (human)
Alcohol dehydrogenase 1AEC 1.1.1.1; Alcohol dehydrogenase subunit alphaHomo sapiens (human)
Aldehyde dehydrogenase, dimeric NADP-preferring EC 1.2.1.5; ALDHIII; Aldehyde dehydrogenase 3; Aldehyde dehydrogenase family 3 member A1Homo sapiens (human)

Compounds (13)

CompoundDescription
hydronium ion
felbamateA PEGylated phenylcarbamate derivative that acts as an antagonist of NMDA RECEPTORS. It is used as an anticonvulsant, primarily for the treatment of SEIZURES in severe refractory EPILEPSY.
NADH
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
3-carbamoyloxy-2-phenylpropionic acidstructure given in first source
NADA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
hydratropic aldehyde
SCH 54388metabolite of felbamate; structure in first source
3-carbamoyl-2-phenylpropionaldehydestructure given in first source
4-hydroxy-5-phenyl-1,3-oxazaperhydroin-2-onea felbamate metabolite; structure in first source
5-phenyl-1,3-oxazinane-2,4-dionestructure in first source
creolinfrom refined coal tar oils