| Protein | Synonyms | Taxonomy |
|---|
| Interleukin-3 | IL-3; Hematopoietic growth factor; Mast cell growth factor; MCGF; Multipotential colony-stimulating factor; P-cell-stimulating factor | Homo sapiens (human) |
| Lymphocyte cytosolic protein 2 | SH2 domain-containing leukocyte protein of 76 kDa; SLP-76 tyrosine phosphoprotein; SLP76 | Homo sapiens (human) |
| RAF proto-oncogene serine/threonine-protein kinase | EC 2.7.11.1; Proto-oncogene c-RAF; cRaf; Raf-1 | Homo sapiens (human) |
| Tyrosine-protein kinase Fyn | EC 2.7.10.2; Proto-oncogene Syn; Proto-oncogene c-Fyn; Src-like kinase; SLK; p59-Fyn | Homo sapiens (human) |
| Tyrosine-protein kinase Lyn | EC 2.7.10.2; Lck/Yes-related novel protein tyrosine kinase; V-yes-1 Yamaguchi sarcoma viral related oncogene homolog; p53Lyn; p56Lyn | Homo sapiens (human) |
| Protein kinase C alpha type | PKC-A; PKC-alpha; EC 2.7.11.13 | Homo sapiens (human) |
| Mitogen-activated protein kinase 1 | MAP kinase 1; MAPK 1; EC 2.7.11.24; ERT1; Extracellular signal-regulated kinase 2; ERK-2; MAP kinase isoform p42; p42-MAPK; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK 2 | Homo sapiens (human) |
| RAC-alpha serine/threonine-protein kinase | EC 2.7.11.1; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha | Homo sapiens (human) |
| Dual specificity mitogen-activated protein kinase kinase 2 | MAP kinase kinase 2; MAPKK 2; EC 2.7.12.2; ERK activator kinase 2; MAPK/ERK kinase 2; MEK 2 | Homo sapiens (human) |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | PI3-kinase subunit alpha; PI3K-alpha; PI3Kalpha; PtdIns-3-kinase subunit alpha; EC 2.7.1.137; EC 2.7.1.153; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha; PtdIns-3-kinase subunit p110-alpha; p110alpha; Phosphoinositide 3-k | Homo sapiens (human) |
| Tyrosine-protein kinase SYK | EC 2.7.10.2; Spleen tyrosine kinase; p72-Syk | Homo sapiens (human) |
| Dual specificity mitogen-activated protein kinase kinase 6 | MAP kinase kinase 6; MAPKK 6; EC 2.7.12.2; MAPK/ERK kinase 6; MEK 6; Stress-activated protein kinase kinase 3; SAPK kinase 3; SAPKK-3; SAPKK3 | Homo sapiens (human) |
| Dual specificity mitogen-activated protein kinase kinase 1 | MAP kinase kinase 1; MAPKK 1; MKK1; EC 2.7.12.2; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1 | Homo sapiens (human) |
| Tyrosine-protein kinase BTK | EC 2.7.10.2; Agammaglobulinemia tyrosine kinase; ATK; B-cell progenitor kinase; BPK; Bruton tyrosine kinase | Homo sapiens (human) |
| [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial | EC 2.7.11.2; Pyruvate dehydrogenase kinase isoform 1; PDH kinase 1 | Homo sapiens (human) |
| Mitogen-activated protein kinase 14 | MAP kinase 14; MAPK 14; EC 2.7.11.24; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MAP kinase MXI2; MAX-interacting protein 2; Mitogen-activated protein kinase p38 alpha; MAP kinase p38 alpha; Stress-activated | Homo sapiens (human) |
| Granulocyte-macrophage colony-stimulating factor | GM-CSF; Colony-stimulating factor; CSF; Molgramostin; Sargramostim | Homo sapiens (human) |
| 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | EC 3.1.4.11; PLC-148; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-II; PLC-II; Phospholipase C-gamma-1; PLC-gamma-1 | Homo sapiens (human) |
| Phosphatidylinositol 3-kinase regulatory subunit alpha | PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alpha | Homo sapiens (human) |
| Mitogen-activated protein kinase 8 | MAP kinase 8; MAPK 8; EC 2.7.11.24; JNK-46; Stress-activated protein kinase 1c; SAPK1c; Stress-activated protein kinase JNK1; c-Jun N-terminal kinase 1 | Homo sapiens (human) |
| Growth factor receptor-bound protein 2 | Adapter protein GRB2; Protein Ash; SH2/SH3 adapter GRB2 | Homo sapiens (human) |
| Linker for activation of T-cells family member 1 | 36 kDa phospho-tyrosine adapter protein; pp36; p36-38 | Homo sapiens (human) |
| Interleukin-5 | IL-5; B-cell differentiation factor I; Eosinophil differentiation factor; T-cell replacing factor; TRF | Homo sapiens (human) |
| High affinity immunoglobulin epsilon receptor subunit alpha | Fc-epsilon RI-alpha; FcERI; IgE Fc receptor subunit alpha | Homo sapiens (human) |
| Ras-related C3 botulinum toxin substrate 1 | EC 3.6.5.2; Cell migration-inducing gene 5 protein; Ras-like protein TC25; p21-Rac1 | Homo sapiens (human) |
| GTPase NRas | EC 3.6.5.2; Transforming protein N-Ras | Homo sapiens (human) |
| Son of sevenless homolog 1 | SOS-1 | Homo sapiens (human) |
| Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 | EC 3.1.3.86; Inositol polyphosphate-5-phosphatase D; 3.1.3.56; Inositol polyphosphate-5-phosphatase of 145 kDa; SIP-145; Phosphatidylinositol 4,5-bisphosphate 5-phosphatase; 3.1.3.36; SH2 domain-containing inositol 5'-phosphatase 1; SH2 domain-containing | Homo sapiens (human) |
| Dual specificity mitogen-activated protein kinase kinase 7 | MAP kinase kinase 7; MAPKK 7; EC 2.7.12.2; JNK-activating kinase 2; MAPK/ERK kinase 7; MEK 7; Stress-activated protein kinase kinase 4; SAPK kinase 4; SAPKK-4; SAPKK4; c-Jun N-terminal kinase kinase 2; JNK kinase 2; JNKK 2 | Homo sapiens (human) |
| GTPase HRas | EC 3.6.5.2; H-Ras-1; Ha-Ras; Transforming protein p21; c-H-ras; p21ras | Homo sapiens (human) |
| GTPase KRas | EC 3.6.5.2; K-Ras 2; Ki-Ras; c-K-ras; c-Ki-ras | Homo sapiens (human) |
| Tumor necrosis factor | Cachectin; TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-a | Homo sapiens (human) |
| Dual specificity mitogen-activated protein kinase kinase 4 | MAP kinase kinase 4; MAPKK 4; EC 2.7.12.2; JNK-activating kinase 1; MAPK/ERK kinase 4; MEK 4; SAPK/ERK kinase 1; SEK1; Stress-activated protein kinase kinase 1; SAPK kinase 1; SAPKK-1; SAPKK1; c-Jun N-terminal kinase kinase 1; JNKK | Homo sapiens (human) |
| Dual specificity mitogen-activated protein kinase kinase 3 | MAP kinase kinase 3; MAPKK 3; EC 2.7.12.2; MAPK/ERK kinase 3; MEK 3; Stress-activated protein kinase kinase 2; SAPK kinase 2; SAPKK-2; SAPKK2 | Homo sapiens (human) |
| Cytosolic phospholipase A2 | cPLA2; Phospholipase A2 group IVA | Homo sapiens (human) |
| High affinity immunoglobulin epsilon receptor subunit beta | FcERI; Fc epsilon receptor I beta-chain; IgE Fc receptor subunit beta; Membrane-spanning 4-domains subfamily A member 2 | Homo sapiens (human) |
| Interleukin-4 | IL-4; B-cell stimulatory factor 1; BSF-1; Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra | Homo sapiens (human) |
| Interleukin-13 | IL-13 | Homo sapiens (human) |
| High affinity immunoglobulin epsilon receptor subunit gamma | Fc receptor gamma-chain; FcRgamma; Fc-epsilon RI-gamma; IgE Fc receptor subunit gamma; FceRI gamma | Homo sapiens (human) |
| GRB2-associated-binding protein 2 | GRB2-associated binder 2; Growth factor receptor bound protein 2-associated protein 2; pp100 | Homo sapiens (human) |
| Immunoglobulin heavy constant epsilon | Ig epsilon chain C region; Ig epsilon chain C region ND | Homo sapiens (human) |
| Guanine nucleotide exchange factor VAV3 | VAV-3 | Homo sapiens (human) |
| Compound | Description |
|---|
| Sodium Heparin | |
| Calcium | A basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes. |
| histamine | An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter. |
| phosphatidylinositol 3,4,5-triphosphate | |
| inositol 1,4,5-trisphosphate | Intracellular messenger formed by the action of phospholipase C on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make up the cell membrane. Inositol 1,4,5-trisphosphate is released into the cytoplasm where it releases calcium ions from internal stores within the cell's endoplasmic reticulum. These calcium ions stimulate the activity of B kinase or calmodulin. |
| arachidonic acid | An unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides. It is formed by the synthesis from dietary linoleic acid and is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. |
| leukotriene c4 | The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some VASCULAR SMOOTH MUSCLE. (From Dictionary of Prostaglandins and Related Compounds, 1990) |
| leukotriene d4 | One of the biologically active principles of SRS-A. It is generated from LEUKOTRIENE C4 after partial hydrolysis of the peptide chain, i.e., cleavage of the gamma-glutamyl portion. Its biological actions include stimulation of vascular and nonvascular smooth muscle, and increases in vascular permeability. (From Dictionary of Prostaglandins and Related Compounds, 1990) |
| prostaglandin d2 | The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast cells and is also synthesized by alveolar macrophages. Among its many biological actions, the most important are its bronchoconstrictor, platelet-activating-factor-inhibitory, and cytotoxic effects. |