Page last updated: 2024-10-06

Fatty acyl-CoA biosynthesis

Proteins (16)

ProteinSynonymsTaxonomy
Elongation of very long chain fatty acids protein 7EC 2.3.1.199; 3-keto acyl-CoA synthase ELOVL7; ELOVL fatty acid elongase 7; ELOVL FA elongase 7; Very long chain 3-ketoacyl-CoA synthase 7; Very long chain 3-oxoacyl-CoA synthase 7Homo sapiens (human)
Very long-chain acyl-CoA synthetaseVLACS; VLCS; EC 6.2.1.-; Arachidonate--CoA ligase; 6.2.1.15; Fatty acid transport protein 2; FATP-2; Fatty-acid-coenzyme A ligase, very long-chain 1; Long-chain-fatty-acid--CoA ligase; 6.2.1.3; Phytanate--CoA ligase; 6.2.1.24; Solute carrier family 27 memHomo sapiens (human)
Fatty acid synthaseEC 2.3.1.85; Type I fatty acid synthaseHomo sapiens (human)
Stearoyl-CoA desaturase 5EC 1.14.19.1; Acyl-CoA-desaturase 4; HSCD5; Stearoyl-CoA 9-desaturase; Stearoyl-CoA desaturase 2Homo sapiens (human)
Malonate--CoA ligase ACSF3, mitochondrialEC 6.2.1.n3; Acyl-CoA synthetase family member 3Homo sapiens (human)
ATP-citrate synthaseEC 2.3.3.8; ATP-citrate (pro-S-)-lyase; ACL; Citrate cleavage enzymeHomo sapiens (human)
Stearoyl-CoA desaturasehSCD1; EC 1.14.19.1; Acyl-CoA desaturase; Delta(9)-desaturase; Delta-9 desaturase; Fatty acid desaturaseHomo sapiens (human)
Acetyl-CoA carboxylase 1ACC1; EC 6.4.1.2; Acetyl-Coenzyme A carboxylase alpha; ACC-alphaHomo sapiens (human)
Lysosomal thioesterase PPT2PPT-2; EC 3.1.2.-; S-thioesterase G14Homo sapiens (human)
Palmitoyl-protein thioesterase 1PPT-1; EC 3.1.2.22; Palmitoyl-protein hydrolase 1Homo sapiens (human)
S-acyl fatty acid synthase thioesterase, medium chainEC 3.1.2.14; Augmented in rheumatoid arthritis 1; AURA1; Oleoyl-ACP hydrolase; Thioesterase 2; TE2; Thioesterase II; Thioesterase domain-containing protein 1Homo sapiens (human)
Hydroxyacyl-thioester dehydratase type 2, mitochondrialHsHTD2; EC 4.2.1.59; 3-hydroxyacyl-[acyl-carrier-protein] dehydrataseHomo sapiens (human)
Solute carrier family 27 member 3EC 6.2.1.-; Arachidonate--CoA ligase; 6.2.1.15; Long-chain fatty acid transport protein 3; FATP-3; Fatty acid transport protein 3; Very long-chain acyl-CoA synthetase homolog 3; VLCS-3Homo sapiens (human)
Carbonyl reductase family member 4EC 1.-.-.-; 3-ketoacyl-[acyl-carrier-protein] reductase beta subunit; KAR beta subunit; 3-oxoacyl-[acyl-carrier-protein] reductase; 1.1.1.-; Quinone reductase CBR4; Short chain dehydrogenase/reductase family 45C member 1Homo sapiens (human)
Estradiol 17-beta-dehydrogenase 8EC 1.1.1.62; 17-beta-hydroxysteroid dehydrogenase 8; 17-beta-HSD 8; 3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit; KAR alpha subunit; 3-oxoacyl-[acyl-carrier-protein] reductase; 1.1.1.-; Protein Ke6; Ke-6; Really interesting new gene 2 proteinHomo sapiens (human)
ATPase MORC2EC 3.6.1.-; MORC family CW-type zinc finger protein 2; Zinc finger CW-type coiled-coil domain protein 1Homo sapiens (human)

Compounds (26)

CompoundDescription
hydronium ion
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
citric acid, anhydrous
Orthophosphate
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
hydrogen carbonate
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
palmitic acidA common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids.
adenosine monophosphateAdenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
OxaloacetateAn anionic form of oxaloacetic acid.
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
oleoyl-coenzyme aRN given refers to (Z)-isomer
3-hydroxyoctadecanoyl-coenzyme A
Coenzyme A
lignoceroyl-coenzyme A
arachidonyl-coenzyme A
3-ketostearoyl-coenzyme A
decanoic acid
Acetyl Coenzyme AAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.
Palmitoyl Coenzyme AA fatty acid coenzyme derivative which plays a key role in fatty acid oxidation and biosynthesis.
Malonyl Coenzyme AA coenzyme A derivative which plays a key role in the fatty acid synthesis in the cytoplasmic and microsomal systems.
stearoyl-coenzyme A
creolinfrom refined coal tar oils