Page last updated: 2024-10-06
Fatty acyl-CoA biosynthesis
Proteins (16)
| Protein | Synonyms | Taxonomy |
|---|---|---|
| Elongation of very long chain fatty acids protein 7 | EC 2.3.1.199; 3-keto acyl-CoA synthase ELOVL7; ELOVL fatty acid elongase 7; ELOVL FA elongase 7; Very long chain 3-ketoacyl-CoA synthase 7; Very long chain 3-oxoacyl-CoA synthase 7 | Homo sapiens (human) |
| Very long-chain acyl-CoA synthetase | VLACS; VLCS; EC 6.2.1.-; Arachidonate--CoA ligase; 6.2.1.15; Fatty acid transport protein 2; FATP-2; Fatty-acid-coenzyme A ligase, very long-chain 1; Long-chain-fatty-acid--CoA ligase; 6.2.1.3; Phytanate--CoA ligase; 6.2.1.24; Solute carrier family 27 mem | Homo sapiens (human) |
| Fatty acid synthase | EC 2.3.1.85; Type I fatty acid synthase | Homo sapiens (human) |
| Stearoyl-CoA desaturase 5 | EC 1.14.19.1; Acyl-CoA-desaturase 4; HSCD5; Stearoyl-CoA 9-desaturase; Stearoyl-CoA desaturase 2 | Homo sapiens (human) |
| Malonate--CoA ligase ACSF3, mitochondrial | EC 6.2.1.n3; Acyl-CoA synthetase family member 3 | Homo sapiens (human) |
| ATP-citrate synthase | EC 2.3.3.8; ATP-citrate (pro-S-)-lyase; ACL; Citrate cleavage enzyme | Homo sapiens (human) |
| Stearoyl-CoA desaturase | hSCD1; EC 1.14.19.1; Acyl-CoA desaturase; Delta(9)-desaturase; Delta-9 desaturase; Fatty acid desaturase | Homo sapiens (human) |
| Acetyl-CoA carboxylase 1 | ACC1; EC 6.4.1.2; Acetyl-Coenzyme A carboxylase alpha; ACC-alpha | Homo sapiens (human) |
| Lysosomal thioesterase PPT2 | PPT-2; EC 3.1.2.-; S-thioesterase G14 | Homo sapiens (human) |
| Palmitoyl-protein thioesterase 1 | PPT-1; EC 3.1.2.22; Palmitoyl-protein hydrolase 1 | Homo sapiens (human) |
| S-acyl fatty acid synthase thioesterase, medium chain | EC 3.1.2.14; Augmented in rheumatoid arthritis 1; AURA1; Oleoyl-ACP hydrolase; Thioesterase 2; TE2; Thioesterase II; Thioesterase domain-containing protein 1 | Homo sapiens (human) |
| Hydroxyacyl-thioester dehydratase type 2, mitochondrial | HsHTD2; EC 4.2.1.59; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase | Homo sapiens (human) |
| Solute carrier family 27 member 3 | EC 6.2.1.-; Arachidonate--CoA ligase; 6.2.1.15; Long-chain fatty acid transport protein 3; FATP-3; Fatty acid transport protein 3; Very long-chain acyl-CoA synthetase homolog 3; VLCS-3 | Homo sapiens (human) |
| Carbonyl reductase family member 4 | EC 1.-.-.-; 3-ketoacyl-[acyl-carrier-protein] reductase beta subunit; KAR beta subunit; 3-oxoacyl-[acyl-carrier-protein] reductase; 1.1.1.-; Quinone reductase CBR4; Short chain dehydrogenase/reductase family 45C member 1 | Homo sapiens (human) |
| Estradiol 17-beta-dehydrogenase 8 | EC 1.1.1.62; 17-beta-hydroxysteroid dehydrogenase 8; 17-beta-HSD 8; 3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit; KAR alpha subunit; 3-oxoacyl-[acyl-carrier-protein] reductase; 1.1.1.-; Protein Ke6; Ke-6; Really interesting new gene 2 protein | Homo sapiens (human) |
| ATPase MORC2 | EC 3.6.1.-; MORC family CW-type zinc finger protein 2; Zinc finger CW-type coiled-coil domain protein 1 | Homo sapiens (human) |
Compounds (26)
| Compound | Description |
|---|---|
| hydronium ion | |
| Carbon Dioxide | A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. |
| citric acid, anhydrous | |
| Orthophosphate | |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| hydrogen carbonate | |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| palmitic acid | A common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids. |
| adenosine monophosphate | Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| Oxaloacetate | An anionic form of oxaloacetic acid. |
| adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| oleoyl-coenzyme a | RN given refers to (Z)-isomer |
| 3-hydroxyoctadecanoyl-coenzyme A | |
| Coenzyme A | |
| lignoceroyl-coenzyme A | |
| arachidonyl-coenzyme A | |
| 3-ketostearoyl-coenzyme A | |
| decanoic acid | |
| Acetyl Coenzyme A | Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent. |
| Palmitoyl Coenzyme A | A fatty acid coenzyme derivative which plays a key role in fatty acid oxidation and biosynthesis. |
| Malonyl Coenzyme A | A coenzyme A derivative which plays a key role in the fatty acid synthesis in the cytoplasmic and microsomal systems. |
| stearoyl-coenzyme A | |
| creolin | from refined coal tar oils |