Page last updated: 2024-10-06

FAS signaling pathway ( CD95 )

Proteins (30)

ProteinSynonymsTaxonomy
Receptor-interacting serine/threonine-protein kinase 2EC 2.7.11.1; CARD-containing interleukin-1 beta-converting enzyme-associated kinase; CARD-containing IL-1 beta ICE-kinase; RIP-like-interacting CLARP kinase; Receptor-interacting protein 2; RIP-2; Tyrosine-protein kinase RIPK2; 2.7.10.2Homo sapiens (human)
Serine/threonine-protein kinase PAK 1EC 2.7.11.1; Alpha-PAK; p21-activated kinase 1; PAK-1; p65-PAKHomo sapiens (human)
Mitogen-activated protein kinase kinase kinase 1EC 2.7.11.25; MAPK/ERK kinase kinase 1; MEK kinase 1; MEKK 1Homo sapiens (human)
Caspase-8CASP-8; EC 3.4.22.61; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; MACHHomo sapiens (human)
Tumor necrosis factor ligand superfamily member 6Apoptosis antigen ligand; APTL; CD95 ligand; CD95-L; Fas antigen ligand; Fas ligand; FasLHomo sapiens (human)
Mitogen-activated protein kinase kinase kinase 7EC 2.7.11.25; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1Homo sapiens (human)
Transcription factor AP-1Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39Homo sapiens (human)
Poly [ADP-ribose] polymerase 1PARP-1; EC 2.4.2.30; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; DNA ADP-ribosyltransferase PARP1; 2.4.2.-; NAD(+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1; Protein poly-ADP-ribosyltransferase PARP1; 2.4.2.-Homo sapiens (human)
Caspase-3CASP-3; EC 3.4.22.56; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1Homo sapiens (human)
Mitogen-activated protein kinase 8MAP kinase 8; MAPK 8; EC 2.7.11.24; JNK-46; Stress-activated protein kinase 1c; SAPK1c; Stress-activated protein kinase JNK1; c-Jun N-terminal kinase 1Homo sapiens (human)
Caspase-6CASP-6; EC 3.4.22.59; Apoptotic protease Mch-2Homo sapiens (human)
DNA-dependent protein kinase catalytic subunitDNA-PK catalytic subunit; DNA-PKcs; EC 2.7.11.1; DNPK1; p460Homo sapiens (human)
FAS-associated factor 1hFAF1; UBX domain-containing protein 12; UBX domain-containing protein 3AHomo sapiens (human)
Tyrosine-protein phosphatase non-receptor type 13EC 3.1.3.48; Fas-associated protein-tyrosine phosphatase 1; FAP-1; PTP-BAS; Protein-tyrosine phosphatase 1E; PTP-E1; hPTPE1; Protein-tyrosine phosphatase PTPL1Homo sapiens (human)
Tumor necrosis factor receptor superfamily member 6Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptorHomo sapiens (human)
CASP8 and FADD-like apoptosis regulatorCaspase homolog; CASH; Caspase-eight-related protein; Casper; Caspase-like apoptosis regulatory protein; CLARP; Cellular FLICE-like inhibitory protein; c-FLIP; FADD-like antiapoptotic molecule 1; FLAME-1; Inhibitor of FLICE; I-FLICE; MACH-related inducer Homo sapiens (human)
Retinoblastoma-associated protein p105-Rb; p110-RB1; pRb; Rb; pp110Homo sapiens (human)
Dual specificity mitogen-activated protein kinase kinase 4MAP kinase kinase 4; MAPKK 4; EC 2.7.12.2; JNK-activating kinase 1; MAPK/ERK kinase 4; MEK 4; SAPK/ERK kinase 1; SEK1; Stress-activated protein kinase kinase 1; SAPK kinase 1; SAPKK-1; SAPKK1; c-Jun N-terminal kinase kinase 1; JNKKHomo sapiens (human)
Caspase-7CASP-7; EC 3.4.22.60; Apoptotic protease Mch-3; CMH-1; ICE-like apoptotic protease 3; ICE-LAP3Homo sapiens (human)
Serine/threonine-protein kinase PAK 2EC 2.7.11.1; Gamma-PAK; PAK65; S6/H4 kinase; p21-activated kinase 2; PAK-2; p58Homo sapiens (human)
Caspase-10CASP-10; EC 3.4.22.63; Apoptotic protease Mch-4; FAS-associated death domain protein interleukin-1B-converting enzyme 2; FLICE2; ICE-like apoptotic protease 4Homo sapiens (human)
FAS-associated death domain proteinFAS-associating death domain-containing protein; Growth-inhibiting gene 3 protein; Mediator of receptor induced toxicity; Protein FADDHomo sapiens (human)
DNA fragmentation factor subunit alphaDNA fragmentation factor 45 kDa subunit; DFF-45; Inhibitor of CAD; ICADHomo sapiens (human)
Death domain-associated protein 6Daxx; hDaxx; ETS1-associated protein 1; EAP1; Fas death domain-associated proteinHomo sapiens (human)
DNA fragmentation factor subunit betaEC 3.-.-.-; Caspase-activated deoxyribonuclease; CAD; Caspase-activated DNase; Caspase-activated nuclease; CPAN; DNA fragmentation factor 40 kDa subunit; DFF-40Homo sapiens (human)
Prelamin-A/CHomo sapiens (human)
Lamin-B1Homo sapiens (human)
Rho GDP-dissociation inhibitor 2Rho GDI 2; Ly-GDI; Rho-GDI betaHomo sapiens (human)
Lamin-B2Homo sapiens (human)
Spectrin alpha chain, non-erythrocytic 1Alpha-II spectrin; Fodrin alpha chain; Spectrin, non-erythroid alpha subunitHomo sapiens (human)

Compounds (1)

CompoundDescription
Orthophosphate