Page last updated: 2024-10-06

Extracellular matrix organization

Proteins (133)

ProteinSynonymsTaxonomy
Thrombospondin-1Glycoprotein GHomo sapiens (human)
Basigin5F7; Collagenase stimulatory factor; Extracellular matrix metalloproteinase inducer; EMMPRIN; Hepatoma-associated antigen; HAb18G; Leukocyte activation antigen M6; OK blood group antigen; Tumor cell-derived collagenase stimulatory factor; TCSFHomo sapiens (human)
Integrin alpha-8Homo sapiens (human)
Serine protease HTRA1EC 3.4.21.-; High-temperature requirement A serine peptidase 1; L56; Serine protease 11Homo sapiens (human)
Integrin alpha-11Homo sapiens (human)
Interstitial collagenaseEC 3.4.24.7; Fibroblast collagenase; Matrix metalloproteinase-1; MMP-1Homo sapiens (human)
Integrin beta-3Platelet membrane glycoprotein IIIa; GPIIIaHomo sapiens (human)
Integrin beta-1Fibronectin receptor subunit beta; Glycoprotein IIa; GPIIA; VLA-4 subunit betaHomo sapiens (human)
Neutrophil elastaseEC 3.4.21.37; Bone marrow serine protease; Elastase-2; Human leukocyte elastase; HLE; Medullasin; PMN elastaseHomo sapiens (human)
Cathepsin GCG; EC 3.4.21.20Homo sapiens (human)
Integrin alpha-IIbGPalpha IIb; GPIIb; Platelet membrane glycoprotein IIbHomo sapiens (human)
MatrilysinEC 3.4.24.23; Matrin; Matrix metalloproteinase-7; MMP-7; Pump-1 protease; Uterine metalloproteinaseHomo sapiens (human)
Protein kinase C alpha typePKC-A; PKC-alpha; EC 2.7.11.13Homo sapiens (human)
Vascular endothelial growth factor receptor 2VEGFR-2; EC 2.7.10.1; Fetal liver kinase 1; FLK-1; Kinase insert domain receptor; KDR; Protein-tyrosine kinase receptor flk-1Homo sapiens (human)
Matrix metalloproteinase-14MMP-14; EC 3.4.24.80; MMP-X1; Membrane-type matrix metalloproteinase 1; MT-MMP 1; MTMMP1; Membrane-type-1 matrix metalloproteinase; MT1-MMP; MT1MMPHomo sapiens (human)
Discoidin domain-containing receptor 2Discoidin domain receptor 2; EC 2.7.10.1; CD167 antigen-like family member B; Discoidin domain-containing receptor tyrosine kinase 2; Neurotrophic tyrosine kinase, receptor-related 3; Receptor protein-tyrosine kinase TKT; Tyrosine-protein kinase TYRO10Homo sapiens (human)
NicastrinHomo sapiens (human)
Integrin alpha-MCD11 antigen-like family member B; CR-3 alpha chain; Cell surface glycoprotein MAC-1 subunit alpha; Leukocyte adhesion receptor MO1; Neutrophil adherence receptorHomo sapiens (human)
Laminin subunit alpha-1Laminin A chain; Laminin-1 subunit alpha; Laminin-3 subunit alpha; S-laminin subunit alpha; S-LAM alphaHomo sapiens (human)
Laminin subunit beta-1Laminin B1 chain; Laminin-1 subunit beta; Laminin-10 subunit beta; Laminin-12 subunit beta; Laminin-2 subunit beta; Laminin-6 subunit beta; Laminin-8 subunit betaHomo sapiens (human)
FibronectinFN; Cold-insoluble globulin; CIGHomo sapiens (human)
Integrin alpha-6CD49 antigen-like family member F; VLA-6Homo sapiens (human)
Disintegrin and metalloproteinase domain-containing protein 8ADAM 8; EC 3.4.24.-; Cell surface antigen MS2Homo sapiens (human)
Integrin alpha-9Integrin alpha-RLCHomo sapiens (human)
Protein disulfide-isomerasePDI; EC 5.3.4.1; Cellular thyroid hormone-binding protein; Prolyl 4-hydroxylase subunit beta; p55Homo sapiens (human)
Muscle, skeletal receptor tyrosine-protein kinaseEC 2.7.10.1; Muscle-specific tyrosine-protein kinase receptor; MuSK; Muscle-specific kinase receptorHomo sapiens (human)
Integrin beta-2Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; Complement receptor C3 subunit betaHomo sapiens (human)
Integrin alpha-V Vitronectin receptor; Vitronectin receptor subunit alphaHomo sapiens (human)
Calpain-1 catalytic subunitEC 3.4.22.52; Calcium-activated neutral proteinase 1; CANP 1; Calpain mu-type; Calpain-1 large subunit; Cell proliferation-inducing gene 30 protein; Micromolar-calpain; muCANPHomo sapiens (human)
72 kDa type IV collagenaseEC 3.4.24.24; 72 kDa gelatinase; Gelatinase A; Matrix metalloproteinase-2; MMP-2; TBE-1Homo sapiens (human)
Stromelysin-1SL-1; EC 3.4.24.17; Matrix metalloproteinase-3; MMP-3; Transin-1Homo sapiens (human)
FurinEC 3.4.21.75; Dibasic-processing enzyme; Paired basic amino acid residue-cleaving enzyme; PACEHomo sapiens (human)
Integrin alpha-4CD49 antigen-like family member D; Integrin alpha-IV; VLA-4 subunit alphaHomo sapiens (human)
Matrix metalloproteinase-9MMP-9; EC 3.4.24.35; 92 kDa gelatinase; 92 kDa type IV collagenase; Gelatinase B; GELBHomo sapiens (human)
Integrin alpha-2CD49 antigen-like family member B; Collagen receptor; Platelet membrane glycoprotein Ia; GPIa; VLA-2 subunit alphaHomo sapiens (human)
Integrin beta-5Homo sapiens (human)
Integrin alpha-LCD11 antigen-like family member A; Leukocyte adhesion glycoprotein LFA-1 alpha chain; LFA-1A; Leukocyte function-associated molecule 1 alpha chainHomo sapiens (human)
Neutrophil collagenaseEC 3.4.24.34; Matrix metalloproteinase-8; MMP-8; PMNL collagenase; PMNL-CLHomo sapiens (human)
Integrin alpha-3CD49 antigen-like family member C; FRP-2; Galactoprotein B3; GAPB3; VLA-3 subunit alphaHomo sapiens (human)
Macrophage metalloelastaseMME; EC 3.4.24.65; Macrophage elastase; ME; hME; Matrix metalloproteinase-12; MMP-12Homo sapiens (human)
Collagenase 3EC 3.4.24.-; Matrix metalloproteinase-13; MMP-13Homo sapiens (human)
Presenilin-1PS-1; EC 3.4.23.-; Protein S182Homo sapiens (human)
Matrix metalloproteinase-15MMP-15; EC 3.4.24.-; Membrane-type matrix metalloproteinase 2; MT-MMP 2; MTMMP2; Membrane-type-2 matrix metalloproteinase; MT2-MMP; MT2MMP; SMCP-2Homo sapiens (human)
DystroglycanDystrophin-associated glycoprotein 1Homo sapiens (human)
PlectinPCN; PLTN; Hemidesmosomal protein 1; HD1; Plectin-1Homo sapiens (human)
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2EC 1.14.11.4; Lysyl hydroxylase 2; LH2Homo sapiens (human)
Metalloproteinase inhibitor 1Erythroid-potentiating activity; EPA; Fibroblast collagenase inhibitor; Collagenase inhibitor; Tissue inhibitor of metalloproteinases 1; TIMP-1Homo sapiens (human)
Plasminogen activator inhibitor 1PAI; PAI-1; Endothelial plasminogen activator inhibitor; Serpin E1Homo sapiens (human)
Stromelysin-2SL-2; EC 3.4.24.22; Matrix metalloproteinase-10; MMP-10; Transin-2Homo sapiens (human)
Integrin beta-6Homo sapiens (human)
Peptidyl-prolyl cis-trans isomerase BPPIase B; EC 5.2.1.8; CYP-S1; Cyclophilin B; Rotamase B; S-cyclophilin; SCYLPHomo sapiens (human)
Integrin alpha-1CD49 antigen-like family member A; Laminin and collagen receptor; VLA-1Homo sapiens (human)
Cadherin-1CAM 120/80; Epithelial cadherin; E-cadherin; UvomorulinHomo sapiens (human)
Matrix metalloproteinase-19MMP-19; EC 3.4.24.-; Matrix metalloproteinase RASI; Matrix metalloproteinase-18; MMP-18Homo sapiens (human)
Peripheral plasma membrane protein CASKhCASK; EC 2.7.11.1; Calcium/calmodulin-dependent serine protein kinase; Protein lin-2 homologHomo sapiens (human)
Integrin alpha-5CD49 antigen-like family member E; Fibronectin receptor subunit alpha; Integrin alpha-F; VLA-5Homo sapiens (human)
Fibroblast growth factor 2FGF-2; Basic fibroblast growth factor; bFGF; Heparin-binding growth factor 2; HBGF-2Homo sapiens (human)
Stromelysin-3SL-3; ST3; EC 3.4.24.-; Matrix metalloproteinase-11; MMP-11Homo sapiens (human)
Integrin beta-7Gut homing receptor beta subunitHomo sapiens (human)
Epithelial discoidin domain-containing receptor 1Epithelial discoidin domain receptor 1; EC 2.7.10.1; CD167 antigen-like family member A; Cell adhesion kinase; Discoidin receptor tyrosine kinase; HGK2; Mammary carcinoma kinase 10; MCK-10; Protein-tyrosine kinase 3A; Protein-tyrosine kinase RTK-6; TRK E;Homo sapiens (human)
CD44 antigenCDw44; Epican; Extracellular matrix receptor III; ECMR-III; GP90 lymphocyte homing/adhesion receptor; HUTCH-I; Heparan sulfate proteoglycan; Hermes antigen; Hyaluronate receptor; Phagocytic glycoprotein 1; PGP-1; Phagocytic glycoprotein I; PGP-IHomo sapiens (human)
Transforming growth factor beta-2 proproteinCetermin; Glioblastoma-derived T-cell suppressor factor; G-TSFHomo sapiens (human)
Calpain small subunit 1CSS1; Calcium-activated neutral proteinase small subunit; CANP small subunit; Calcium-dependent protease small subunit; CDPS; Calcium-dependent protease small subunit 1; Calpain regulatory subunitHomo sapiens (human)
Serpin H147 kDa heat shock protein; Arsenic-transactivated protein 3; AsTP3; Cell proliferation-inducing gene 14 protein; Collagen-binding protein; Colligin; Rheumatoid arthritis-related antigen RA-A47Homo sapiens (human)
Alpha-2-macroglobulinAlpha-2-M; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5Homo sapiens (human)
Transforming growth factor beta-3 proproteinHomo sapiens (human)
DecorinBone proteoglycan II; PG-S2; PG40Homo sapiens (human)
SPARCBasement-membrane protein 40; BM-40; Osteonectin; ON; Secreted protein acidic and rich in cysteineHomo sapiens (human)
CalpastatinCalpain inhibitor; Sperm BS-17 componentHomo sapiens (human)
Bone sialoprotein 2Bone sialoprotein II; BSP II; Cell-binding sialoprotein; Integrin-binding sialoproteinHomo sapiens (human)
Cartilage oligomeric matrix proteinCOMP; Thrombospondin-5; TSP5Homo sapiens (human)
Basement membrane-specific heparan sulfate proteoglycan core proteinHSPG; Perlecan; PLCHomo sapiens (human)
Junctional adhesion molecule AJAM-A; Junctional adhesion molecule 1; JAM-1; Platelet F11 receptor; Platelet adhesion molecule 1; PAM-1Homo sapiens (human)
Integrin alpha-10Homo sapiens (human)
Transforming growth factor beta-1 proproteinHomo sapiens (human)
Integrin beta-8Homo sapiens (human)
AgrinHomo sapiens (human)
Latent-transforming growth factor beta-binding protein 1LTBP-1; Transforming growth factor beta-1-binding protein 1; TGF-beta1-BP-1Homo sapiens (human)
Integrin alpha-DADB2; CD11 antigen-like family member D; Leukointegrin alpha DHomo sapiens (human)
Prolyl 3-hydroxylase 1EC 1.14.11.7; Growth suppressor 1; Leucine- and proline-enriched proteoglycan 1; Leprecan-1Homo sapiens (human)
VitronectinVN; S-protein; Serum-spreading factor; V75Homo sapiens (human)
Vascular cell adhesion protein 1V-CAM 1; VCAM-1; INCAM-100Homo sapiens (human)
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1EC 1.14.11.4; Lysyl hydroxylase 1; LH1Homo sapiens (human)
Metalloproteinase inhibitor 2CSC-21K; Tissue inhibitor of metalloproteinases 2; TIMP-2Homo sapiens (human)
Fibrillin-1Homo sapiens (human)
OsteopontinBone sialoprotein 1; Nephropontin; Secreted phosphoprotein 1; SPP-1; Urinary stone protein; UropontinHomo sapiens (human)
DystrophinHomo sapiens (human)
ElastinTropoelastinHomo sapiens (human)
TenascinTN; Cytotactin; GMEM; GP 150-225; Glioma-associated-extracellular matrix antigen; Hexabrachion; JI; Myotendinous antigen; Neuronectin; Tenascin-C; TN-CHomo sapiens (human)
LumicanKeratan sulfate proteoglycan lumican; KSPG lumicanHomo sapiens (human)
Cartilage-associated proteinHomo sapiens (human)
Dentin sialophosphoproteinHomo sapiens (human)
Junctional adhesion molecule CJAM-C; JAM-2; Junctional adhesion molecule 3; JAM-3Homo sapiens (human)
Junctional adhesion molecule BJAM-B; Junctional adhesion molecule 2; JAM-2; Vascular endothelial junction-associated molecule; VE-JAMHomo sapiens (human)
Netrin-4Beta-netrin; Hepar-derived netrin-like proteinHomo sapiens (human)
Platelet endothelial cell adhesion moleculePECAM-1; EndoCAM; GPIIA'; PECA1Homo sapiens (human)
Dentin matrix acidic phosphoprotein 1DMP-1; Dentin matrix protein 1Homo sapiens (human)
Laminin subunit alpha-5Laminin-10 subunit alpha; Laminin-11 subunit alpha; Laminin-15 subunit alphaHomo sapiens (human)
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3Homo sapiens (human)
Low-density lipoprotein receptor-related protein 4LRP-4; Multiple epidermal growth factor-like domains 7Homo sapiens (human)
Fibrinogen alpha chainHomo sapiens (human)
Fibrinogen beta chainHomo sapiens (human)
Fibrinogen gamma chainHomo sapiens (human)
Hyaluronan and proteoglycan link protein 1Cartilage-linking protein 1; Cartilage-link protein; Proteoglycan link proteinHomo sapiens (human)
Laminin subunit gamma-1Laminin B2 chain; Laminin-1 subunit gamma; Laminin-10 subunit gamma; Laminin-11 subunit gamma; Laminin-2 subunit gamma; Laminin-3 subunit gamma; Laminin-4 subunit gamma; Laminin-6 subunit gamma; Laminin-7 subunit gamma; Laminin-8 subunit gamma; Laminin-9 Homo sapiens (human)
Alpha-actinin-1Alpha-actinin cytoskeletal isoform; F-actin cross-linking protein; Non-muscle alpha-actinin-1Homo sapiens (human)
Nidogen-1NID-1; EntactinHomo sapiens (human)
Integrin beta-4GP150Homo sapiens (human)
Integrin alpha-XCD11 antigen-like family member C; Leu M5; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95Homo sapiens (human)
Tenascin-XTN-X; Hexabrachion-like proteinHomo sapiens (human)
Laminin subunit alpha-2Laminin M chain; Laminin-12 subunit alpha; Laminin-2 subunit alpha; Laminin-4 subunit alpha; Merosin heavy chainHomo sapiens (human)
Integrin alpha-EHML-1 antigen; Integrin alpha-IEL; Mucosal lymphocyte 1 antigenHomo sapiens (human)
Collagen alpha-1(XV) chainHomo sapiens (human)
Collagen alpha-1(XVIII) chainHomo sapiens (human)
CD151 antigenGP27; Membrane glycoprotein SFA-1; Platelet-endothelial tetraspan antigen 3; PETA-3; Tetraspanin-24; Tspan-24Homo sapiens (human)
Laminin subunit beta-2Laminin B1s chain; Laminin-11 subunit beta; Laminin-14 subunit beta; Laminin-15 subunit beta; Laminin-3 subunit beta; Laminin-4 subunit beta; Laminin-7 subunit beta; Laminin-9 subunit beta; S-laminin subunit beta; S-LAM betaHomo sapiens (human)
Integrin alpha-7Homo sapiens (human)
Laminin subunit beta-3Epiligrin subunit bata; Kalinin B1 chain; Kalinin subunit beta; Laminin B1k chain; Laminin-5 subunit beta; Nicein subunit betaHomo sapiens (human)
Laminin subunit gamma-2Cell-scattering factor 140 kDa subunit; CSF 140 kDa subunit; Epiligrin subunit gamma; Kalinin subunit gamma; Kalinin/nicein/epiligrin 100 kDa subunit; Ladsin 140 kDa subunit; Laminin B2t chain; Laminin-5 subunit gamma; Large adhesive scatter factor 140 kDHomo sapiens (human)
Laminin subunit alpha-4Laminin-14 subunit alpha; Laminin-8 subunit alpha; Laminin-9 subunit alphaHomo sapiens (human)
Laminin subunit alpha-3Epiligrin 170 kDa subunit; E170; Epiligrin subunit alpha; Kalinin subunit alpha; Laminin-5 subunit alpha; Laminin-6 subunit alpha; Laminin-7 subunit alpha; Nicein subunit alphaHomo sapiens (human)
SH3 and PX domain-containing protein 2AAdapter protein TKS5; Five SH3 domain-containing protein; SH3 multiple domains protein 1; Tyrosine kinase substrate with five SH3 domainsHomo sapiens (human)
5-phosphohydroxy-L-lysine phospho-lyaseEC 4.2.3.134; Alanine--glyoxylate aminotransferase 2-like 2Homo sapiens (human)
Signal peptide, CUB and EGF-like domain-containing protein 3Homo sapiens (human)
Latent-transforming growth factor beta-binding protein 4LTBP-4Homo sapiens (human)
Peroxidasin homologEC 1.11.1.7; Melanoma-associated antigen MG50; Vascular peroxidase 1; p53-responsive gene 2 proteinHomo sapiens (human)
Tenascin-RTN-R; Janusin; RestrictinHomo sapiens (human)
Testican-3SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3Homo sapiens (human)
OpticinOculoglycanHomo sapiens (human)
Fibulin-5FIBL-5; Developmental arteries and neural crest EGF-like protein; Dance; Urine p50 protein; UP50Homo sapiens (human)
Neurexin-1Neurexin I-alpha; Neurexin-1-alphaHomo sapiens (human)
Trafficking protein particle complex subunit 4Hematopoietic stem/progenitor cell protein 172; Synbindin; TRS23 homologHomo sapiens (human)
Laminin subunit gamma-3Laminin-12 subunit gamma; Laminin-14 subunit gamma; Laminin-15 subunit gammaHomo sapiens (human)

Compounds (15)

CompoundDescription
Succinate
ammonium hydroxideThe hydroxy salt of ammonium ion. It is formed when AMMONIA reacts with water molecules in solution.
CopperA heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55.
CalciumA basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
ironA metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
ManganeseA trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
Orthophosphate
ascorbic acidA six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.
uridine diphosphateA uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety.
Hydrogen PeroxideA strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials.
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
alpha-Ketoglutarate