| Protein | Synonyms | Taxonomy |
|---|
| 3-phosphoinositide-dependent protein kinase 1 | hPDK1; EC 2.7.11.1 | Homo sapiens (human) |
| Epidermal growth factor receptor | EC 2.7.10.1; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1 | Homo sapiens (human) |
| Estrogen receptor | ER; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1 | Homo sapiens (human) |
| Heat shock protein HSP 90-alpha | EC 3.6.4.10; Heat shock 86 kDa; HSP 86; HSP86; Lipopolysaccharide-associated protein 2; LAP-2; LPS-associated protein 2; Renal carcinoma antigen NY-REN-38 | Homo sapiens (human) |
| Insulin-like growth factor 1 receptor | EC 2.7.10.1; Insulin-like growth factor I receptor; IGF-I receptor | Homo sapiens (human) |
| Proto-oncogene tyrosine-protein kinase Src | EC 2.7.10.2; Proto-oncogene c-Src; pp60c-src; p60-Src | Homo sapiens (human) |
| G1/S-specific cyclin-D1 | B-cell lymphoma 1 protein; BCL-1; BCL-1 oncogene; PRAD1 oncogene | Homo sapiens (human) |
| Mitogen-activated protein kinase 3 | MAP kinase 3; MAPK 3; EC 2.7.11.24; ERT2; Extracellular signal-regulated kinase 1; ERK-1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p44-ERK1 | Homo sapiens (human) |
| Mitogen-activated protein kinase 1 | MAP kinase 1; MAPK 1; EC 2.7.11.24; ERT1; Extracellular signal-regulated kinase 2; ERK-2; MAP kinase isoform p42; p42-MAPK; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK 2 | Homo sapiens (human) |
| RAC-alpha serine/threonine-protein kinase | EC 2.7.11.1; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha | Homo sapiens (human) |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | PI3-kinase subunit alpha; PI3K-alpha; PI3Kalpha; PtdIns-3-kinase subunit alpha; EC 2.7.1.137; EC 2.7.1.153; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha; PtdIns-3-kinase subunit p110-alpha; p110alpha; Phosphoinositide 3-k | Homo sapiens (human) |
| Focal adhesion kinase 1 | FADK 1; EC 2.7.10.2; Focal adhesion kinase-related nonkinase; FRNK; Protein phosphatase 1 regulatory subunit 71; PPP1R71; Protein-tyrosine kinase 2; p125FAK; pp125FAK | Homo sapiens (human) |
| Protein kinase C zeta type | EC 2.7.11.13; nPKC-zeta | Homo sapiens (human) |
| Sphingosine 1-phosphate receptor 3 | S1P receptor 3; S1P3; Endothelial differentiation G-protein coupled receptor 3; Sphingosine 1-phosphate receptor Edg-3; S1P receptor Edg-3 | Homo sapiens (human) |
| Sphingosine kinase 1 | SK 1; SPK 1; EC 2.7.1.91; Acetyltransferase SPHK1; 2.3.1.- | Homo sapiens (human) |
| Apoptosis regulator Bcl-2 | | Homo sapiens (human) |
| Cyclin-dependent kinase inhibitor 1B | Cyclin-dependent kinase inhibitor p27; p27Kip1 | Homo sapiens (human) |
| Exportin-1 | Exp1; Chromosome region maintenance 1 protein homolog | Homo sapiens (human) |
| Forkhead box protein O3 | AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1 | Homo sapiens (human) |
| Cyclic AMP-responsive element-binding protein 1 | CREB-1; cAMP-responsive element-binding protein 1 | Homo sapiens (human) |
| Serum response factor | SRF | Homo sapiens (human) |
| Protein arginine N-methyltransferase 1 | EC 2.1.1.319; Histone-arginine N-methyltransferase PRMT1; Interferon receptor 1-bound protein 4 | Homo sapiens (human) |
| Proto-oncogene c-Fos | Cellular oncogene fos; G0/G1 switch regulatory protein 7 | Homo sapiens (human) |
| ETS domain-containing protein Elk-1 | | Homo sapiens (human) |
| Proheparin-binding EGF-like growth factor | | Homo sapiens (human) |
| Striatin | | Homo sapiens (human) |
| Serine/threonine-protein kinase Kist | EC 2.7.11.1; Kinase interacting with stathmin; PAM COOH-terminal interactor protein 2; P-CIP2; U2AF homology motif kinase 1 | Homo sapiens (human) |
| Compound | Description |
|---|
| Nitric Oxide | A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP. |
| Arginine | An essential amino acid that is physiologically active in the L-form. |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| guanosine diphosphate | A guanine nucleotide containing two phosphate groups esterified to the sugar moiety. |
| Guanosine Monophosphate | A guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature. |
| Guanosine Diphosphate | A guanine nucleotide containing two phosphate groups esterified to the sugar moiety. |
| sapropterin | RN given refers to parent cpd; co-factor required for catalytic activity of nitric oxide synthases |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| Coenzyme A | |
| Palmitoyl Coenzyme A | A fatty acid coenzyme derivative which plays a key role in fatty acid oxidation and biosynthesis. |
| sphingosine 1-phosphate | RN given refers to (R-(R*,S*-(E)))-isomer; RN for cpd without isomeric designation not available 8/89 |