Page last updated: 2024-10-06

Enalapril Action Pathway

Proteins (3)

ProteinSynonymsTaxonomy
ReninEC 3.4.23.15; AngiotensinogenaseHomo sapiens (human)
AngiotensinogenSerpin A8Homo sapiens (human)
Angiotensin-converting enzyme ACE; EC 3.2.1.-; EC 3.4.15.1; Dipeptidyl carboxypeptidase I; Kininase IIHomo sapiens (human)

Compounds (3)

CompoundDescription
angiotensin iiAn octapeptide that is a potent but labile vasoconstrictor. It is produced from angiotensin I after the removal of two amino acids at the C-terminal by ANGIOTENSIN CONVERTING ENZYME. The amino acid in position 5 varies in different species. To block VASOCONSTRICTION and HYPERTENSION effect of angiotensin II, patients are often treated with ACE INHIBITORS or with ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS.
EnalaprilatThe active metabolite of ENALAPRIL and one of the potent, intravenously administered, ANGIOTENSIN-CONVERTING ENZYME INHIBITORS. It is an effective agent for the treatment of essential hypertension and has beneficial hemodynamic effects in heart failure. The drug produces renal vasodilation with an increase in sodium excretion.
angiotensin i, ile(5)-