Page last updated: 2024-10-06

Electron Transport Chain (COVID-19 Disease Map)

Proteins (11)

ProteinSynonymsTaxonomy
CatalaseEC 1.11.1.6Homo sapiens (human)
Phospholipid hydroperoxide glutathione peroxidasePHGPx; EC 1.11.1.12; Glutathione peroxidase 4; GPx-4; GSHPx-4Homo sapiens (human)
Superoxide dismutase [Cu-Zn]EC 1.15.1.1; Superoxide dismutase 1; hSod1Homo sapiens (human)
Glutathione reductase, mitochondrialGR; GRase; EC 1.8.1.7Homo sapiens (human)
NAD-dependent protein deacetylase sirtuin-3, mitochondrialhSIRT3; EC 2.3.1.286; Regulatory protein SIR2 homolog 3; SIR2-like protein 3Homo sapiens (human)
Cytochrome cHomo sapiens (human)
Transcription factor A, mitochondrialmtTFA; Mitochondrial transcription factor 1; MtTF1; Transcription factor 6; TCF-6; Transcription factor 6-like 2Homo sapiens (human)
Glutathione peroxidase 1GPx-1; GSHPx-1; EC 1.11.1.9; Cellular glutathione peroxidaseHomo sapiens (human)
Thioredoxin, mitochondrialMTRX; Mt-Trx; Thioredoxin-2Homo sapiens (human)
Thioredoxin reductase 2, mitochondrialEC 1.8.1.9; Selenoprotein Z; SelZ; TR-beta; Thioredoxin reductase TR3Homo sapiens (human)
Superoxide dismutase [Mn], mitochondrialEC 1.15.1.1Homo sapiens (human)

Compounds (18)

CompoundDescription
Orthophosphate
GlutathioneA tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides.
ironA metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
IronA metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
Glutathione DisulfideA GLUTATHIONE dimer formed by a disulfide bond between the cysteine sulfhydryl side chains during the course of being oxidized.
NADH
ubiquinol 1
HydrogenThe first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.
Adenosine TriphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
Hydrogen PeroxideA strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials.
hydroxide ion
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
ubiquinone q1interacts with iron atom to form acceptor quinone complex
NADA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
paraquatA poisonous dipyridilium compound used as contact herbicide. Contact with concentrated solutions causes irritation of the skin, cracking and shedding of the nails, and delayed healing of cuts and wounds.
creolinfrom refined coal tar oils