| Compound | Description |
|---|
| dinoprostone | The most common and most biologically active of the mammalian prostaglandins. It exhibits most biological activities characteristic of prostaglandins and has been used extensively as an oxytocic agent. The compound also displays a protective effect on the intestinal mucosa. |
| dinoprost | A naturally occurring prostaglandin that has oxytocic, luteolytic, and abortifacient activities. Due to its vasocontractile properties, the compound has a variety of other biological actions. |
| epoprostenol | A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from PROSTAGLANDIN ENDOPEROXIDES in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension (HYPERTENSION, PULMONARY). |
| 11-hydroxy-5,8,12,14-eicosatetraenoic acid | RN given refers to cpd without isomeric designation |
| arachidonic acid | An unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides. It is formed by the synthesis from dietary linoleic acid and is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. |
| prostaglandin h2 | A cyclic endoperoxide intermediate produced by the action of CYCLOOXYGENASE on ARACHIDONIC ACID. It is further converted by a series of specific enzymes to the series 2 prostaglandins. |
| thromboxane a2 | An unstable intermediate between the prostaglandin endoperoxides and thromboxane B2. The compound has a bicyclic oxaneoxetane structure. It is a potent inducer of platelet aggregation and causes vasoconstriction. It is the principal component of rabbit aorta contracting substance (RCS). |
| 15-keto-13,14-dihydroprostaglandin e2 | RN given refers to (5Z,11alpha)-isomer; structure in first source |
| 15-ketoprostaglandin e2 | metabolite of PGE2; RN given refers to (5Z,11alpha,13E)-isomer |
| 15-hydroxy-5,8,11,13-eicosatetraenoic acid | potent & selective inhibitor of platelet lipoxygenase; RN given refers to cpd without isomeric designation |
| prostaglandin a2 | RN given refers to (5Z,13E,15S)-isomer |
| prostaglandin b2 | RN given refers to (5Z,13E,15S)-isomer |
| prostaglandin g2 | |
| 9-deoxy-delta-9-prostaglandin d2 | has potent antineoplastic & weak smooth muscle contracting activities; structure given in first source |
| 9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin d2 | PGD2 metabolite in human plasma |
| 15-ketoprostaglandin f2alpha | |
| 6-ketoprostaglandin f1 alpha | The physiologically active and stable hydrolysis product of EPOPROSTENOL. Found in nearly all mammalian tissue. |
| 6-ketoprostaglandin e1 | potent direct dilator of pulmonary & systemic circulations of newborn lamb |
| 11-dehydro-thromboxane b2 | structure given in first source |
| 20-hydroxyprostaglandin E2 | found in rat seminal fluid |
| 13,14-dihydro-15-ketoprostaglandin d2 | PGD2 metabolite; RN given refers to (5Z,9alpha)-isomer |
| 15-keto-13,14-dihydroprostaglandin f2alpha | main metabolite of PGF2alpha in plasma after allergen provoked asthma; RN given refers to (5Z,9alpha,11alpha)-isomer; structure |
| thromboxane b2 | A stable, physiologically active compound formed in vivo from the prostaglandin endoperoxides. It is important in the platelet-release reaction (release of ADP and serotonin). |
| 12-hydroxy-5,8,10-heptadecatrienoic acid | metabolite of arachidonic acid in blood platelet suspension; RN given refers to cpd without isomeric designation |
| 15-hydroxy-5,8,11,13-eicosatetraenoic acid | potent & selective inhibitor of platelet lipoxygenase; RN given refers to cpd without isomeric designation |
| 15-deoxy-delta(12,14)-prostaglandin j2 | 15-deoxy-PGJ2 is also available; check for double bonds (indicated by delta) at 12 and 14 positions |
| tetranorprostaglandin E1 | urinary metabolite of prostaglandins E |
| prostaglandin d2 | The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast cells and is also synthesized by alveolar macrophages. Among its many biological actions, the most important are its bronchoconstrictor, platelet-activating-factor-inhibitory, and cytotoxic effects. |