Page last updated: 2024-10-06

EGFR downregulation

Proteins (14)

ProteinSynonymsTaxonomy
Epidermal growth factor receptorEC 2.7.10.1; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1Homo sapiens (human)
Cell division control protein 42 homologEC 3.6.5.2; G25K GTP-binding proteinHomo sapiens (human)
Epidermal growth factor receptor substrate 15Protein Eps15; Protein AF-1pHomo sapiens (human)
Hepatocyte growth factor-regulated tyrosine kinase substrateHrs; Protein pp110Homo sapiens (human)
Pro-epidermal growth factorEGFHomo sapiens (human)
Tyrosine-protein phosphatase non-receptor type 12EC 3.1.3.48; PTP-PEST; Protein-tyrosine phosphatase G1; PTPG1Homo sapiens (human)
Tyrosine-protein phosphatase non-receptor type 3EC 3.1.3.48; Protein-tyrosine phosphatase H1; PTP-H1Homo sapiens (human)
Epsin-1EH domain-binding mitotic phosphoprotein; EPS-15-interacting protein 1Homo sapiens (human)
SH3 domain-containing kinase-binding protein 1CD2-binding protein 3; CD2BP3; Cbl-interacting protein of 85 kDa; Human Src family kinase-binding protein 1; HSB-1Homo sapiens (human)
E3 ubiquitin-protein ligase CBLEC 2.3.2.27; Casitas B-lineage lymphoma proto-oncogene; Proto-oncogene c-Cbl; RING finger protein 55; RING-type E3 ubiquitin transferase CBL; Signal transduction protein CBLHomo sapiens (human)
Protein sprouty homolog 2Spry-2Homo sapiens (human)
Rho guanine nucleotide exchange factor 7Beta-Pix; COOL-1; PAK-interacting exchange factor beta; p85Homo sapiens (human)
Receptor-type tyrosine-protein phosphatase kappaProtein-tyrosine phosphatase kappa; R-PTP-kappa; EC 3.1.3.48Homo sapiens (human)
Epidermal growth factor receptor substrate 15-like 1Eps15-related protein; Eps15RHomo sapiens (human)

Compounds (5)

CompoundDescription
Orthophosphate
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Guanosine MonophosphateA guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.