Page last updated: 2024-10-06

Downstream signaling events of B Cell Receptor (BCR)

Proteins (66)

ProteinSynonymsTaxonomy
NF-kappa-B inhibitor epsilonNF-kappa-BIE; I-kappa-B-epsilon; IkB-E; IkB-epsilon; IkappaBepsilonHomo sapiens (human)
Mucosa-associated lymphoid tissue lymphoma translocation protein 1EC 3.4.22.-; MALT lymphoma-associated translocation; ParacaspaseHomo sapiens (human)
Inhibitor of nuclear factor kappa-B kinase subunit betaI-kappa-B-kinase beta; IKK-B; IKK-beta; IkBKB; EC 2.7.11.10; I-kappa-B kinase 2; IKK2; Nuclear factor NF-kappa-B inhibitor kinase beta; NFKBIKB; Serine/threonine protein kinase IKBKB; 2.7.11.1Homo sapiens (human)
Inhibitor of nuclear factor kappa-B kinase subunit alphaI-kappa-B kinase alpha; IKK-A; IKK-alpha; IkBKA; IkappaB kinase; EC 2.7.11.10; Conserved helix-loop-helix ubiquitous kinase; I-kappa-B kinase 1; IKK1; Nuclear factor NF-kappa-B inhibitor kinase alpha; NFKBIKA; Transcription factor 16; TCF-16Homo sapiens (human)
Protein kinase C beta typePKC-B; PKC-beta; EC 2.7.11.13Homo sapiens (human)
NF-kappa-B inhibitor alphaI-kappa-B-alpha; IkB-alpha; IkappaBalpha; Major histocompatibility complex enhancer-binding protein MAD3Homo sapiens (human)
Proteasome subunit beta type-9EC 3.4.25.1; Low molecular mass protein 2; Macropain chain 7; Multicatalytic endopeptidase complex chain 7; Proteasome chain 7; Proteasome subunit beta-1i; Really interesting new gene 12 proteinHomo sapiens (human)
Transcription factor p65Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3Homo sapiens (human)
Calcineurin subunit B type 1Protein phosphatase 2B regulatory subunit 1; Protein phosphatase 3 regulatory subunit B alpha isoform 1Homo sapiens (human)
Mitogen-activated protein kinase kinase kinase 7EC 2.7.11.25; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1Homo sapiens (human)
Proteasome subunit beta type-1Macropain subunit C5; Multicatalytic endopeptidase complex subunit C5; Proteasome component C5; Proteasome gamma chainHomo sapiens (human)
Proteasome activator complex subunit 311S regulator complex subunit gamma; REG-gamma; Activator of multicatalytic protease subunit 3; Ki nuclear autoantigen; Proteasome activator 28 subunit gamma; PA28g; PA28gammaHomo sapiens (human)
Cullin-1CUL-1Homo sapiens (human)
Nuclear factor NF-kappa-B p105 subunitDNA-binding factor KBF1; EBP-1; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1Homo sapiens (human)
Proteasome subunit beta type-3Proteasome chain 13; Proteasome component C10-II; Proteasome theta chainHomo sapiens (human)
Proto-oncogene c-RelHomo sapiens (human)
26S proteasome non-ATPase regulatory subunit 1026S proteasome regulatory subunit p28; Gankyrin; p28(GANK)Homo sapiens (human)
NF-kappa-B essential modulatorNEMO; FIP-3; IkB kinase-associated protein 1; IKKAP1; Inhibitor of nuclear factor kappa-B kinase subunit gamma; I-kappa-B kinase subunit gamma; IKK-gamma; IKKG; IkB kinase subunit gamma; NF-kappa-B essential modifierHomo sapiens (human)
Calmodulin-1Homo sapiens (human)
Proteasome subunit beta type-8EC 3.4.25.1; Low molecular mass protein 7; Macropain subunit C13; Multicatalytic endopeptidase complex subunit C13; Proteasome component C13; Proteasome subunit beta-5i; Really interesting new gene 10 proteinHomo sapiens (human)
Proteasome subunit beta type-5EC 3.4.25.1; Macropain epsilon chain; Multicatalytic endopeptidase complex epsilon chain; Proteasome chain 6; Proteasome epsilon chain; Proteasome subunit MB1; Proteasome subunit XHomo sapiens (human)
Proteasome subunit beta type-2Macropain subunit C7-I; Multicatalytic endopeptidase complex subunit C7-I; Proteasome component C7-IHomo sapiens (human)
Peptidyl-prolyl cis-trans isomerase A PPIase A; EC 5.2.1.8; Cyclophilin A; Cyclosporin A-binding protein; Rotamase AHomo sapiens (human)
Peptidyl-prolyl cis-trans isomerase FKBP1APPIase FKBP1A; EC 5.2.1.8; 12 kDa FK506-binding protein; 12 kDa FKBP; FKBP-12; Calstabin-1; FK506-binding protein 1A; FKBP-1A; Immunophilin FKBP12; RotamaseHomo sapiens (human)
Proteasome subunit beta type-11EC 3.4.25.1; Proteasome subunit beta-5tHomo sapiens (human)
26S proteasome non-ATPase regulatory subunit 1126S proteasome regulatory subunit RPN6; 26S proteasome regulatory subunit S9; 26S proteasome regulatory subunit p44.5Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 1226S proteasome regulatory subunit RPN5; 26S proteasome regulatory subunit p55Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 14EC 3.4.19.-; 26S proteasome regulatory subunit RPN11; 26S proteasome-associated PAD1 homolog 1Homo sapiens (human)
Proteasome subunit alpha type-7Proteasome subunit RC6-1; Proteasome subunit XAPC7Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 326S proteasome regulatory subunit RPN3; 26S proteasome regulatory subunit S3; Proteasome subunit p58Homo sapiens (human)
26S proteasome regulatory subunit 6A26S proteasome AAA-ATPase subunit RPT5; Proteasome 26S subunit ATPase 3; Proteasome subunit P50; Tat-binding protein 1; TBP-1Homo sapiens (human)
Proteasome subunit alpha type-130 kDa prosomal protein; PROS-30; Macropain subunit C2; Multicatalytic endopeptidase complex subunit C2; Proteasome component C2; Proteasome nu chainHomo sapiens (human)
Proteasome subunit alpha type-2Macropain subunit C3; Multicatalytic endopeptidase complex subunit C3; Proteasome component C3Homo sapiens (human)
Proteasome subunit alpha type-3Macropain subunit C8; Multicatalytic endopeptidase complex subunit C8; Proteasome component C8Homo sapiens (human)
Proteasome subunit alpha type-4Macropain subunit C9; Multicatalytic endopeptidase complex subunit C9; Proteasome component C9; Proteasome subunit LHomo sapiens (human)
Proteasome subunit alpha type-5Macropain zeta chain; Multicatalytic endopeptidase complex zeta chain; Proteasome zeta chainHomo sapiens (human)
Proteasome subunit beta type-426 kDa prosomal protein; HsBPROS26; PROS-26; Macropain beta chain; Multicatalytic endopeptidase complex beta chain; Proteasome beta chain; Proteasome chain 3; HsN3Homo sapiens (human)
Proteasome subunit beta type-6EC 3.4.25.1; Macropain delta chain; Multicatalytic endopeptidase complex delta chain; Proteasome delta chain; Proteasome subunit YHomo sapiens (human)
26S proteasome regulatory subunit 726S proteasome AAA-ATPase subunit RPT1; Proteasome 26S subunit ATPase 2; Protein MSS1Homo sapiens (human)
Proteasome subunit beta type-10EC 3.4.25.1; Low molecular mass protein 10; Macropain subunit MECl-1; Multicatalytic endopeptidase complex subunit MECl-1; Proteasome MECl-1; Proteasome subunit beta-2iHomo sapiens (human)
26S proteasome regulatory subunit 6B26S proteasome AAA-ATPase subunit RPT3; MB67-interacting protein; MIP224; Proteasome 26S subunit ATPase 4; Tat-binding protein 7; TBP-7Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 826S proteasome regulatory subunit RPN12; 26S proteasome regulatory subunit S14; p31Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 726S proteasome regulatory subunit RPN8; 26S proteasome regulatory subunit S12; Mov34 protein homolog; Proteasome subunit p40Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 426S proteasome regulatory subunit RPN10; 26S proteasome regulatory subunit S5A; Antisecretory factor 1; AF; ASF; Multiubiquitin chain-binding proteinHomo sapiens (human)
26S proteasome complex subunit SEM126S proteasome complex subunit DSS1; Deleted in split hand/split foot protein 1; Split hand/foot deleted protein 1; Split hand/foot malformation type 1 proteinHomo sapiens (human)
Proteasome subunit alpha type-627 kDa prosomal protein; PROS-27; p27K; Macropain iota chain; Multicatalytic endopeptidase complex iota chain; Proteasome iota chainHomo sapiens (human)
26S proteasome regulatory subunit 4P26s4; 26S proteasome AAA-ATPase subunit RPT2; Proteasome 26S subunit ATPase 1Homo sapiens (human)
26S proteasome regulatory subunit 826S proteasome AAA-ATPase subunit RPT6; Proteasome 26S subunit ATPase 5; Proteasome subunit p45; Thyroid hormone receptor-interacting protein 1; TRIP1; p45/SUGHomo sapiens (human)
26S proteasome regulatory subunit 10B26S proteasome AAA-ATPase subunit RPT4; Proteasome 26S subunit ATPase 6; Proteasome subunit p42Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 226S proteasome regulatory subunit RPN1; 26S proteasome regulatory subunit S2; 26S proteasome subunit p97; Protein 55.11; Tumor necrosis factor type 1 receptor-associated protein 2Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 626S proteasome regulatory subunit RPN7; 26S proteasome regulatory subunit S10; Breast cancer-associated protein SGA-113M; Phosphonoformate immuno-associated protein 4; Proteasome regulatory particle subunit p44S10; p42AHomo sapiens (human)
Proteasome subunit alpha-type 8Proteasome alpha 4 subunit; Alpha4s; Proteasome subunit alpha-type 7-likeHomo sapiens (human)
Proteasome subunit beta type-7EC 3.4.25.1; Macropain chain Z; Multicatalytic endopeptidase complex chain Z; Proteasome subunit ZHomo sapiens (human)
26S proteasome non-ATPase regulatory subunit 126S proteasome regulatory subunit RPN2; 26S proteasome regulatory subunit S1; 26S proteasome subunit p112Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 1326S proteasome regulatory subunit RPN9; 26S proteasome regulatory subunit S11; 26S proteasome regulatory subunit p40.5Homo sapiens (human)
S-phase kinase-associated protein 1Cyclin-A/CDK2-associated protein p19; p19A; Organ of Corti protein 2; OCP-2; Organ of Corti protein II; OCP-II; RNA polymerase II elongation factor-like protein; SIII; Transcription elongation factor B polypeptide 1-like; p19skp1Homo sapiens (human)
Proteasome activator complex subunit 111S regulator complex subunit alpha; REG-alpha; Activator of multicatalytic protease subunit 1; Interferon gamma up-regulated I-5111 protein; IGUP I-5111; Proteasome activator 28 subunit alpha; PA28a; PA28alphaHomo sapiens (human)
Proteasome activator complex subunit 211S regulator complex subunit beta; REG-beta; Activator of multicatalytic protease subunit 2; Proteasome activator 28 subunit beta; PA28b; PA28betaHomo sapiens (human)
26S proteasome non-ATPase regulatory subunit 926S proteasome regulatory subunit p27Homo sapiens (human)
B-cell lymphoma/leukemia 10B-cell CLL/lymphoma 10; Bcl-10; CARD-containing molecule enhancing NF-kappa-B; CARD-like apoptotic protein; hCLAP; CED-3/ICH-1 prodomain homologous E10-like regulator; CIPER; Cellular homolog of vCARMEN; cCARMEN; Cellular-E10; c-E10; Mammalian CARD-contaiHomo sapiens (human)
Proteasome activator complex subunit 4Proteasome activator PA200Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 526S protease subunit S5 basic; 26S proteasome subunit S5BHomo sapiens (human)
Proteasome inhibitor PI31 subunithPI31Homo sapiens (human)
Caspase recruitment domain-containing protein 11CARD-containing MAGUK protein 1; Carma 1Homo sapiens (human)
F-box/WD repeat-containing protein 11F-box and WD repeats protein beta-TrCP2; F-box/WD repeat-containing protein 1B; Homologous to Slimb protein; HOSHomo sapiens (human)
F-box/WD repeat-containing protein 1AE3RSIkappaB; Epididymis tissue protein Li 2a; F-box and WD repeats protein beta-TrCP; pIkappaBalpha-E3 receptor subunitHomo sapiens (human)

Compounds (7)

CompoundDescription
CalciumA basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
IronA metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
ZincA metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
Guanosine MonophosphateA guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
Guanosine DiphosphateA guanine nucleotide containing two phosphate groups esterified to the sugar moiety.
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.