Page last updated: 2024-10-06

Downregulation of TGF-beta receptor signaling

Proteins (16)

ProteinSynonymsTaxonomy
E3 ubiquitin-protein ligase SMURF1hSMURF1; EC 2.3.2.26; HECT-type E3 ubiquitin transferase SMURF1; SMAD ubiquitination regulatory factor 1; SMAD-specific E3 ubiquitin-protein ligase 1Homo sapiens (human)
Protein phosphatase 1 regulatory subunit 15AGrowth arrest and DNA damage-inducible protein GADD34; Myeloid differentiation primary response protein MyD116 homologHomo sapiens (human)
TGF-beta receptor type-1TGFR-1; EC 2.7.11.30; Activin A receptor type II-like protein kinase of 53kD; Activin receptor-like kinase 5; ALK-5; ALK5; Serine/threonine-protein kinase receptor R4; SKR4; TGF-beta type I receptor; Transforming growth factor-beta receptor type I; TGF-beHomo sapiens (human)
Myotubularin-related protein 4EC 3.1.3.48; FYVE domain-containing dual specificity protein phosphatase 2; FYVE-DSP2; Zinc finger FYVE domain-containing protein 11Homo sapiens (human)
Exportin-1Exp1; Chromosome region maintenance 1 protein homologHomo sapiens (human)
TGF-beta receptor type-2TGFR-2; EC 2.7.11.30; TGF-beta type II receptor; Transforming growth factor-beta receptor type II; TGF-beta receptor type II; TbetaR-IIHomo sapiens (human)
E3 ubiquitin-protein ligase SMURF2hSMURF2; EC 2.3.2.26; HECT-type E3 ubiquitin transferase SMURF2; SMAD ubiquitination regulatory factor 2; SMAD-specific E3 ubiquitin-protein ligase 2Homo sapiens (human)
Mothers against decapentaplegic homolog 3MAD homolog 3; Mad3; Mothers against DPP homolog 3; hMAD-3; JV15-2; SMAD family member 3; SMAD 3; Smad3; hSMAD3Homo sapiens (human)
Mothers against decapentaplegic homolog 2MAD homolog 2; Mothers against DPP homolog 2; JV18-1; Mad-related protein 2; hMAD-2; SMAD family member 2; SMAD 2; Smad2; hSMAD2Homo sapiens (human)
Mothers against decapentaplegic homolog 7MAD homolog 7; Mothers against DPP homolog 7; Mothers against decapentaplegic homolog 8; MAD homolog 8; Mothers against DPP homolog 8; SMAD family member 7; SMAD 7; Smad7; hSMAD7Homo sapiens (human)
Transforming growth factor beta-1 proproteinHomo sapiens (human)
Protein TMEPAIProstate transmembrane protein androgen induced 1; Solid tumor-associated 1 protein; Transmembrane prostate androgen-induced proteinHomo sapiens (human)
Serine-threonine kinase receptor-associated proteinMAP activator with WD repeats; UNR-interacting protein; WD-40 repeat protein PT-WDHomo sapiens (human)
E3 ubiquitin-protein ligase CHIPEC 2.3.2.27; Antigen NY-CO-7; CLL-associated antigen KW-8; Carboxy terminus of Hsp70-interacting protein; RING-type E3 ubiquitin transferase CHIP; STIP1 homology and U box-containing protein 1Homo sapiens (human)
BMP and activin membrane-bound inhibitor homologNon-metastatic gene A protein; Putative transmembrane protein NMAHomo sapiens (human)
E3 ubiquitin-protein ligase NEDD4-like EC 2.3.2.26; HECT-type E3 ubiquitin transferase NED4L; NEDD4.2; Nedd4-2Homo sapiens (human)

Compounds (2)

CompoundDescription
Orthophosphate
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)