Page last updated: 2024-10-06

Downregulation of ERBB2 signaling

Proteins (11)

ProteinSynonymsTaxonomy
Receptor tyrosine-protein kinase erbB-2EC 2.7.10.1; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2Homo sapiens (human)
Heat shock protein HSP 90-alphaEC 3.6.4.10; Heat shock 86 kDa; HSP 86; HSP86; Lipopolysaccharide-associated protein 2; LAP-2; LPS-associated protein 2; Renal carcinoma antigen NY-REN-38Homo sapiens (human)
Megakaryocyte-associated tyrosine-protein kinaseEC 2.7.10.2; CSK homologous kinase; CHK; Hematopoietic consensus tyrosine-lacking kinase; Protein kinase HYL; Tyrosine-protein kinase CTKHomo sapiens (human)
Ubiquitin carboxyl-terminal hydrolase 8EC 3.4.19.12; Deubiquitinating enzyme 8; Ubiquitin isopeptidase Y; hUBPy; Ubiquitin thioesterase 8; Ubiquitin-specific-processing protease 8Homo sapiens (human)
Tyrosine-protein phosphatase non-receptor type 12EC 3.1.3.48; PTP-PEST; Protein-tyrosine phosphatase G1; PTPG1Homo sapiens (human)
Hsp90 co-chaperone Cdc37Hsp90 chaperone protein kinase-targeting subunit; p50Cdc37Homo sapiens (human)
Tyrosine-protein phosphatase non-receptor type 18EC 3.1.3.48; Brain-derived phosphataseHomo sapiens (human)
ErbinDensin-180-like protein; Erbb2-interacting protein; Protein LAP2Homo sapiens (human)
E3 ubiquitin-protein ligase CHIPEC 2.3.2.27; Antigen NY-CO-7; CLL-associated antigen KW-8; Carboxy terminus of Hsp70-interacting protein; RING-type E3 ubiquitin transferase CHIP; STIP1 homology and U box-containing protein 1Homo sapiens (human)
E3 ubiquitin-protein ligase NRDP1EC 2.3.2.27; RING finger protein 41; RING-type E3 ubiquitin transferase NRDP1Homo sapiens (human)
Cullin-5CUL-5; Vasopressin-activated calcium-mobilizing receptor 1; VACM-1Homo sapiens (human)

Compounds (4)

CompoundDescription
Orthophosphate
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.