Page last updated: 2024-10-06

Dihydropyrimidinase Deficiency

Proteins (23)

ProteinSynonymsTaxonomy
Thymidylate synthaseTS; TSase; EC 2.1.1.45Homo sapiens (human)
Cytosolic purine 5'-nucleotidaseEC 3.1.3.5; Cytosolic 5'-nucleotidase IIHomo sapiens (human)
Dihydropyrimidine dehydrogenase [NADP(+)]DHPDHase; DPD; EC 1.3.1.2; Dihydrothymine dehydrogenase; Dihydrouracil dehydrogenaseHomo sapiens (human)
Thymidine phosphorylaseTP; EC 2.4.2.4; Gliostatin; Platelet-derived endothelial cell growth factor; PD-ECGF; TdRPaseHomo sapiens (human)
Ribonucleoside-diphosphate reductase subunit M2EC 1.17.4.1; Ribonucleotide reductase small chain; Ribonucleotide reductase small subunitHomo sapiens (human)
Deoxycytidylate deaminaseEC 3.5.4.12; dCMP deaminaseHomo sapiens (human)
Guanine deaminaseGuanase; Guanine aminase; EC 3.5.4.3; Guanine aminohydrolase; GAH; p51-nedasinHomo sapiens (human)
Beta-ureidopropionaseEC 3.5.1.6; BUP-1; Beta-alanine synthase; N-carbamoyl-beta-alanine amidohydrolaseHomo sapiens (human)
Thymidine kinase, cytosolicEC 2.7.1.21Homo sapiens (human)
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrialdUTPase; EC 3.6.1.23; dUTP pyrophosphataseHomo sapiens (human)
Dihydroorotate dehydrogenase (quinone), mitochondrialDHOdehase; EC 1.3.5.2; Dihydroorotate oxidaseHomo sapiens (human)
CAD proteinHomo sapiens (human)
Uridine phosphorylase 2UPase 2; UrdPase 2; EC 2.4.2.3Homo sapiens (human)
DihydropyrimidinaseDHP; DHPase; EC 3.5.2.2; Dihydropyrimidine amidohydrolase; HydantoinaseHomo sapiens (human)
Cytidine deaminaseEC 3.5.4.5; Cytidine aminohydrolaseHomo sapiens (human)
Ribonucleoside-diphosphate reductase subunit M2 BEC 1.17.4.1; TP53-inducible ribonucleotide reductase M2 B; p53-inducible ribonucleotide reductase small subunit 2-like protein; p53R2Homo sapiens (human)
Inosine triphosphate pyrophosphatase ITPase; Inosine triphosphatase; EC 3.6.1.9; Non-canonical purine NTP pyrophosphatase; Non-standard purine NTP pyrophosphatase; Nucleoside-triphosphate diphosphatase; Nucleoside-triphosphate pyrophosphatase; NTPase; Putative oncogene protein hlc14-06-pHomo sapiens (human)
UMP-CMP kinase 2, mitochondrialEC 2.7.4.14; Nucleoside-diphosphate kinase; 2.7.4.6Homo sapiens (human)
Soluble calcium-activated nucleotidase 1SCAN-1; EC 3.6.1.6; Apyrase homolog; Putative MAPK-activating protein PM09; Putative NF-kappa-B-activating protein 107Homo sapiens (human)
Uridine-cytidine kinase-like 1EC 2.7.1.48Homo sapiens (human)
CTP synthase 1EC 6.3.4.2; CTP synthetase 1; UTP--ammonia ligase 1Homo sapiens (human)
Nucleoside diphosphate kinase 6NDK 6; NDP kinase 6; EC 2.7.4.6; Inhibitor of p53-induced apoptosis-alpha; IPIA-alpha; nm23-H6Homo sapiens (human)
GTP:AMP phosphotransferase AK3, mitochondrialEC 2.7.4.10; Adenylate kinase 3; AK 3; Adenylate kinase 3 alpha-like 1Homo sapiens (human)

Compounds (50)

CompoundDescription
phosphoric acidconcise etchant is 37% H3PO4
Orthophosphate
ammonium hydroxideThe hydroxy salt of ammonium ion. It is formed when AMMONIA reacts with water molecules in solution.
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
Adenosine TriphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
glutamineA non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from GLUTAMIC ACID and AMMONIA. It is the principal carrier of NITROGEN in the body and is an important energy source for many cells.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
uridineA ribonucleoside in which RIBOSE is linked to URACIL.
uridine monophosphate5'-Uridylic acid. A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
uridine diphosphateA uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety.
uridine triphosphateUridine 5'-(tetrahydrogen triphosphate). A uracil nucleotide containing three phosphate groups esterified to the sugar moiety.
phosphoribosyl pyrophosphateThe key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides.
hydrogen carbonate
hydroquinone
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
n-carbamoyl-beta-alanineRN given refers to parent cpd
thymineOne of four constituent bases of DNA.
uracilOne of four nucleotide bases in the nucleic acid RNA.
deoxycytidineA nucleoside component of DNA composed of CYTOSINE and DEOXYRIBOSE.
deoxyuridine2'-Deoxyuridine. An antimetabolite that is converted to deoxyuridine triphosphate during DNA synthesis. Laboratory suppression of deoxyuridine is used to diagnose megaloblastic anemias due to vitamin B12 and folate deficiencies.
deoxycytidine monophosphateDeoxycytidine (dihydrogen phosphate). A deoxycytosine nucleotide containing one phosphate group esterified to the deoxyribose moiety in the 2'-,3'- or 5- positions.
deoxyuridine triphosphate
beta-ureidoisobutyric acidstructure given in first source
beta-alanineAn amino acid formed in vivo by the degradation of dihydrouracil and carnosine. Since neuronal uptake and neuronal receptor sensitivity to beta-alanine have been demonstrated, the compound may be a false transmitter replacing GAMMA-AMINOBUTYRIC ACID. A rare genetic disorder, hyper-beta-alaninemia, has been reported.
carbamyl phosphateThe monoanhydride of carbamic acid with PHOSPHORIC ACID. It is an important intermediate metabolite and is synthesized enzymatically by CARBAMYL-PHOSPHATE SYNTHASE (AMMONIA) and CARBAMOYL-PHOSPHATE SYNTHASE (GLUTAMINE-HYDROLYZING).
ribose 1-phosphateRN given refers to (D)-isomer
2-deoxyribose 1-phosphate
quinone
thymidineA nucleoside in which THYMINE is linked to DEOXYRIBOSE.
cytidine monophosphateCytidine (dihydrogen phosphate). A cytosine nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
cytidine diphosphateCytidine 5'-(trihydrogen diphosphate). A cytosine nucleotide containing two phosphate groups esterified to the sugar moiety. Synonyms: CRPP; cytidine pyrophosphate.
cytidineA pyrimidine nucleoside that is composed of the base CYTOSINE linked to the five-carbon sugar D-RIBOSE.
cytidine triphosphateCytidine 5'-(tetrahydrogen triphosphate). A cytosine nucleotide containing three phosphate groups esterified to the sugar moiety.
dihydrouracil
orotic acidAn intermediate product in PYRIMIDINE synthesis which plays a role in chemical conversions between DIHYDROFOLATE and TETRAHYDROFOLATE.
thymidine monophosphate5-Thymidylic acid. A thymine nucleotide containing one phosphate group esterified to the deoxyribose moiety.
2'-deoxycytidine diphosphate
orotidylic acidstructure
thymidine 5'-diphosphatesee also record for thymidine 3',5'-diphosphate, RN 2863-04-9
Adenosine 3'-Phosphate
L-dihydroorotate
creolinfrom refined coal tar oils
pyrophosphate
3-aminoisobutyric acidRN given refers to cpd without isomeric designation
thymidine 5'-triphosphateRN given refers to parent cpd
2'-deoxyuridylic acidRN given refers to parent cpd
deoxyuridine triphosphate
2'-deoxycytidine 5'-triphosphateRN given refers to unlabeled parent cpd
ureidosuccinic acid, (L)-isomer
5,6-dihydrothymineRN given refers to parent cpd