Page last updated: 2024-10-06

Diclofenac Pathway, Pharmacokinetics

Proteins (18)

ProteinSynonymsTaxonomy
ATP-binding cassette sub-family C member 3EC 7.6.2.-; EC 7.6.2.2; EC 7.6.2.3; Canalicular multispecific organic anion transporter 2; Multi-specific organic anion transporter D; MOAT-D; Multidrug resistance-associated protein 3Homo sapiens (human)
Cytochrome P450 3A4EC 1.14.14.1; 1,4-cineole 2-exo-monooxygenase; 1,8-cineole 2-exo-monooxygenase; 1.14.14.56; Albendazole monooxygenase (sulfoxide-forming); 1.14.14.73; Albendazole sulfoxidase; CYPIIIA3; CYPIIIA4; Cholesterol 25-hydroxylase; Cytochrome P450 3A3; CytochromeHomo sapiens (human)
Cytochrome P450 2C8EC 1.14.14.1; CYPIIC8; Cytochrome P450 IIC2; Cytochrome P450 MP-12; Cytochrome P450 MP-20; Cytochrome P450 form 1; S-mephenytoin 4-hydroxylaseHomo sapiens (human)
Cytochrome P450 2C9 EC 1.14.14.1; (R)-limonene 6-monooxygenase; 1.14.14.53; (S)-limonene 6-monooxygenase; 1.14.14.51; (S)-limonene 7-monooxygenase; 1.14.14.52; CYPIIC9; Cholesterol 25-hydroxylase; Cytochrome P-450MP; Cytochrome P450 MP-4; Cytochrome P450 MP-8; Cytochrome P45Homo sapiens (human)
Cytochrome P450 2B6EC 1.14.13.-; 1,4-cineole 2-exo-monooxygenase; CYPIIB6; Cytochrome P450 IIB1Homo sapiens (human)
Cytochrome P450 2C19EC 1.14.14.1; (R)-limonene 6-monooxygenase; 1.14.14.53; (S)-limonene 6-monooxygenase; 1.14.14.51; (S)-limonene 7-monooxygenase; 1.14.14.52; CYPIIC17; CYPIIC19; Cytochrome P450-11A; Cytochrome P450-254C; Fenbendazole monooxygenase (4'-hydroxylating); 1.14.Homo sapiens (human)
Canalicular multispecific organic anion transporter 1ATP-binding cassette sub-family C member 2; Canalicular multidrug resistance protein; Multidrug resistance-associated protein 2; 7.6.2.2Homo sapiens (human)
Broad substrate specificity ATP-binding cassette transporter ABCG2EC 7.6.2.2; ATP-binding cassette sub-family G member 2; Breast cancer resistance protein; CDw338; Mitoxantrone resistance-associated protein; Placenta-specific ATP-binding cassette transporter; Urate exporterHomo sapiens (human)
Glutathione S-transferase Mu 1EC 2.5.1.18; GST HB subunit 4; GST class-mu 1; GSTM1-1; GSTM1a-1a; GSTM1b-1b; GTH4Homo sapiens (human)
Glutathione S-transferase A1EC 2.5.1.18; 13-hydroperoxyoctadecadienoate peroxidase; 1.11.1.-; Androst-5-ene-3,17-dione isomerase; 5.3.3.-; GST HA subunit 1; GST class-alpha member 1; GST-epsilon; GSTA1-1; GTH1Homo sapiens (human)
Glutathione S-transferase PEC 2.5.1.18; GST class-pi; GSTP1-1Homo sapiens (human)
UDP-glucuronosyltransferase 2B7UDPGT 2B7; UGT2B7; EC 2.4.1.17; 3,4-catechol estrogen-specific UDPGT; UDP-glucuronosyltransferase 2B9; UDPGT 2B9; UDPGTh-2Homo sapiens (human)
Solute carrier family 22 member 8Organic anion transporter 3; hOAT3Homo sapiens (human)
Solute carrier family 22 member 11Organic anion transporter 4Homo sapiens (human)
Solute carrier family 22 member 7Novel liver transporter; Organic anion transporter 2; hOAT2Homo sapiens (human)
Cytochrome P450 2C18EC 1.14.14.1; CYPIIC18; Cytochrome P450-6b/29cHomo sapiens (human)
cDNA FLJ31202 fis, clone KIDNE2003188, highly similar to Homo sapiens solute carrier family 22 Homo sapiens (human)
Solute carrier organic anion transporter family member Homo sapiens (human)

Compounds (3)

CompoundDescription
1-O-(2-((2',6'-dichlorophenyl)amino)phenylacetyl)glucopyranuronic acida diclofenac metabolite; structure in first source
5-hydroxydiclofenacstructure in first source
4'-hydroxydiclofenacmetabolite of diclofenac; structure in first source