Page last updated: 2024-10-06

Desipramine Metabolism Pathway

Proteins (3)

ProteinSynonymsTaxonomy
Cytochrome P450 2D6EC 1.14.14.-; CYPIID6; Cholesterol 25-hydroxylase; Cytochrome P450-DB1; Debrisoquine 4-hydroxylaseHomo sapiens (human)
Sodium-dependent serotonin transporterSERT; 5HT transporter; 5HTT; Solute carrier family 6 member 4Homo sapiens (human)
Sodium-dependent noradrenaline transporter Norepinephrine transporter; NET; Solute carrier family 6 member 2Homo sapiens (human)

Compounds (6)

CompoundDescription
hydronium ion
desipramineA tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
2-hydroxydesipramineRN given refers to parent cpd
creolinfrom refined coal tar oils