Desipramine Metabolism Pathway

Proteins (3)

Protein	Synonyms	Taxonomy
Cytochrome P450 2D6	EC 1.14.14.-; CYPIID6; Cholesterol 25-hydroxylase; Cytochrome P450-DB1; Debrisoquine 4-hydroxylase	Homo sapiens (human)
Sodium-dependent serotonin transporter	SERT; 5HT transporter; 5HTT; Solute carrier family 6 member 4	Homo sapiens (human)
Sodium-dependent noradrenaline transporter	Norepinephrine transporter; NET; Solute carrier family 6 member 2	Homo sapiens (human)

Compound	Description
hydronium ion
desipramine	A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
Water	A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Oxygen	An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
2-hydroxydesipramine	RN given refers to parent cpd
creolin	from refined coal tar oils