Page last updated: 2024-10-06

Degradation of the extracellular matrix

Proteins (44)

ProteinSynonymsTaxonomy
Basigin5F7; Collagenase stimulatory factor; Extracellular matrix metalloproteinase inducer; EMMPRIN; Hepatoma-associated antigen; HAb18G; Leukocyte activation antigen M6; OK blood group antigen; Tumor cell-derived collagenase stimulatory factor; TCSFHomo sapiens (human)
Serine protease HTRA1EC 3.4.21.-; High-temperature requirement A serine peptidase 1; L56; Serine protease 11Homo sapiens (human)
Interstitial collagenaseEC 3.4.24.7; Fibroblast collagenase; Matrix metalloproteinase-1; MMP-1Homo sapiens (human)
Neutrophil elastaseEC 3.4.21.37; Bone marrow serine protease; Elastase-2; Human leukocyte elastase; HLE; Medullasin; PMN elastaseHomo sapiens (human)
Cathepsin GCG; EC 3.4.21.20Homo sapiens (human)
MatrilysinEC 3.4.24.23; Matrin; Matrix metalloproteinase-7; MMP-7; Pump-1 protease; Uterine metalloproteinaseHomo sapiens (human)
Matrix metalloproteinase-14MMP-14; EC 3.4.24.80; MMP-X1; Membrane-type matrix metalloproteinase 1; MT-MMP 1; MTMMP1; Membrane-type-1 matrix metalloproteinase; MT1-MMP; MT1MMPHomo sapiens (human)
NicastrinHomo sapiens (human)
Laminin subunit beta-1Laminin B1 chain; Laminin-1 subunit beta; Laminin-10 subunit beta; Laminin-12 subunit beta; Laminin-2 subunit beta; Laminin-6 subunit beta; Laminin-8 subunit betaHomo sapiens (human)
Disintegrin and metalloproteinase domain-containing protein 8ADAM 8; EC 3.4.24.-; Cell surface antigen MS2Homo sapiens (human)
Calpain-1 catalytic subunitEC 3.4.22.52; Calcium-activated neutral proteinase 1; CANP 1; Calpain mu-type; Calpain-1 large subunit; Cell proliferation-inducing gene 30 protein; Micromolar-calpain; muCANPHomo sapiens (human)
72 kDa type IV collagenaseEC 3.4.24.24; 72 kDa gelatinase; Gelatinase A; Matrix metalloproteinase-2; MMP-2; TBE-1Homo sapiens (human)
Stromelysin-1SL-1; EC 3.4.24.17; Matrix metalloproteinase-3; MMP-3; Transin-1Homo sapiens (human)
FurinEC 3.4.21.75; Dibasic-processing enzyme; Paired basic amino acid residue-cleaving enzyme; PACEHomo sapiens (human)
Matrix metalloproteinase-9MMP-9; EC 3.4.24.35; 92 kDa gelatinase; 92 kDa type IV collagenase; Gelatinase B; GELBHomo sapiens (human)
Neutrophil collagenaseEC 3.4.24.34; Matrix metalloproteinase-8; MMP-8; PMNL collagenase; PMNL-CLHomo sapiens (human)
Macrophage metalloelastaseMME; EC 3.4.24.65; Macrophage elastase; ME; hME; Matrix metalloproteinase-12; MMP-12Homo sapiens (human)
Collagenase 3EC 3.4.24.-; Matrix metalloproteinase-13; MMP-13Homo sapiens (human)
Presenilin-1PS-1; EC 3.4.23.-; Protein S182Homo sapiens (human)
Matrix metalloproteinase-15MMP-15; EC 3.4.24.-; Membrane-type matrix metalloproteinase 2; MT-MMP 2; MTMMP2; Membrane-type-2 matrix metalloproteinase; MT2-MMP; MT2MMP; SMCP-2Homo sapiens (human)
Metalloproteinase inhibitor 1Erythroid-potentiating activity; EPA; Fibroblast collagenase inhibitor; Collagenase inhibitor; Tissue inhibitor of metalloproteinases 1; TIMP-1Homo sapiens (human)
Stromelysin-2SL-2; EC 3.4.24.22; Matrix metalloproteinase-10; MMP-10; Transin-2Homo sapiens (human)
Cadherin-1CAM 120/80; Epithelial cadherin; E-cadherin; UvomorulinHomo sapiens (human)
Matrix metalloproteinase-19MMP-19; EC 3.4.24.-; Matrix metalloproteinase RASI; Matrix metalloproteinase-18; MMP-18Homo sapiens (human)
Stromelysin-3SL-3; ST3; EC 3.4.24.-; Matrix metalloproteinase-11; MMP-11Homo sapiens (human)
CD44 antigenCDw44; Epican; Extracellular matrix receptor III; ECMR-III; GP90 lymphocyte homing/adhesion receptor; HUTCH-I; Heparan sulfate proteoglycan; Hermes antigen; Hyaluronate receptor; Phagocytic glycoprotein 1; PGP-1; Phagocytic glycoprotein I; PGP-IHomo sapiens (human)
Calpain small subunit 1CSS1; Calcium-activated neutral proteinase small subunit; CANP small subunit; Calcium-dependent protease small subunit; CDPS; Calcium-dependent protease small subunit 1; Calpain regulatory subunitHomo sapiens (human)
Alpha-2-macroglobulinAlpha-2-M; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5Homo sapiens (human)
DecorinBone proteoglycan II; PG-S2; PG40Homo sapiens (human)
CalpastatinCalpain inhibitor; Sperm BS-17 componentHomo sapiens (human)
Basement membrane-specific heparan sulfate proteoglycan core proteinHSPG; Perlecan; PLCHomo sapiens (human)
Metalloproteinase inhibitor 2CSC-21K; Tissue inhibitor of metalloproteinases 2; TIMP-2Homo sapiens (human)
OsteopontinBone sialoprotein 1; Nephropontin; Secreted phosphoprotein 1; SPP-1; Urinary stone protein; UropontinHomo sapiens (human)
Laminin subunit alpha-5Laminin-10 subunit alpha; Laminin-11 subunit alpha; Laminin-15 subunit alphaHomo sapiens (human)
Laminin subunit gamma-1Laminin B2 chain; Laminin-1 subunit gamma; Laminin-10 subunit gamma; Laminin-11 subunit gamma; Laminin-2 subunit gamma; Laminin-3 subunit gamma; Laminin-4 subunit gamma; Laminin-6 subunit gamma; Laminin-7 subunit gamma; Laminin-8 subunit gamma; Laminin-9 Homo sapiens (human)
Nidogen-1NID-1; EntactinHomo sapiens (human)
Collagen alpha-1(XVIII) chainHomo sapiens (human)
Laminin subunit beta-3Epiligrin subunit bata; Kalinin B1 chain; Kalinin subunit beta; Laminin B1k chain; Laminin-5 subunit beta; Nicein subunit betaHomo sapiens (human)
Laminin subunit gamma-2Cell-scattering factor 140 kDa subunit; CSF 140 kDa subunit; Epiligrin subunit gamma; Kalinin subunit gamma; Kalinin/nicein/epiligrin 100 kDa subunit; Ladsin 140 kDa subunit; Laminin B2t chain; Laminin-5 subunit gamma; Large adhesive scatter factor 140 kDHomo sapiens (human)
Laminin subunit alpha-3Epiligrin 170 kDa subunit; E170; Epiligrin subunit alpha; Kalinin subunit alpha; Laminin-5 subunit alpha; Laminin-6 subunit alpha; Laminin-7 subunit alpha; Nicein subunit alphaHomo sapiens (human)
5-phosphohydroxy-L-lysine phospho-lyaseEC 4.2.3.134; Alanine--glyoxylate aminotransferase 2-like 2Homo sapiens (human)
Signal peptide, CUB and EGF-like domain-containing protein 3Homo sapiens (human)
Testican-3SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3Homo sapiens (human)
OpticinOculoglycanHomo sapiens (human)

Compounds (4)

CompoundDescription
ammonium hydroxideThe hydroxy salt of ammonium ion. It is formed when AMMONIA reacts with water molecules in solution.
CalciumA basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
Orthophosphate
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)