Page last updated: 2024-10-06
Defective pyroptosis
Proteins (4)
| Protein | Synonyms | Taxonomy |
|---|
| DNA polymerase alpha catalytic subunit | EC 2.7.7.7; DNA polymerase alpha catalytic subunit p180 | Homo sapiens (human) |
| DNA primase small subunit | EC 2.7.7.-; DNA primase 49 kDa subunit; p49 | Homo sapiens (human) |
| DNA primase large subunit | DNA primase 58 kDa subunit; p58 | Homo sapiens (human) |
| DNA polymerase alpha subunit B | DNA polymerase alpha 70 kDa subunit | Homo sapiens (human) |
Compounds (6)
| Compound | Description |
|---|
| decitabine | An azacitidine derivative and antineoplastic antimetabolite. It inhibits DNA methyltransferase to re-activate silent genes, limiting METASTASIS and NEOPLASM DRUG RESISTANCE. Decitabine is used in the treatment of MYELODISPLASTIC SYNDROMES, and ACUTE MYELOID LEUKEMIA. |
| deoxyguanosine triphosphate | |
| thymidine 5'-triphosphate | RN given refers to parent cpd |
| s-adenosylmethionine | Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed) |
| 2'-deoxycytidine 5'-triphosphate | RN given refers to unlabeled parent cpd |
| deoxyadenosine diphosphate | RN given refers to parent cpd. |